Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Derya Unutmaz"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious diseases, and immunotherapy. This review explores their intricate involvement in cancer, from early detection to their dual functions in promoting inflammation and m
Externí odkaz:
https://doaj.org/article/96e520efc1a34d76ba479040ea969b24
Autor:
Heather Day, Brayden Yellman, Sarah Hammer, Candace Rond, Jennifer Bell, Saeed Abbaszadeh, Greg Stoddard, Derya Unutmaz, Lucinda Bateman, Suzanne D. Vernon
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionCognitive impairment is experienced by people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute sequelae of COVID-19 (PASC). Patients report difficulty remembering, concentrating, and making decisions. Our ob
Externí odkaz:
https://doaj.org/article/3d06cb5af71649818ab032d22cc05434
Autor:
Dinesh Babu Uthaya Kumar, Marina Yurieva, Jessica Grassmann, Lina Kozhaya, Caleb Dante McBride, Derya Unutmaz, Adam Williams
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The genome is pervasively transcribed to produce a vast array of non-coding RNAs (ncRNAs). Long non-coding RNAs (lncRNAs) are transcripts of >200 nucleotides and are best known for their ability to regulate gene expression. Enhancer RNAs (eRNAs) are
Externí odkaz:
https://doaj.org/article/a0beda4a123b4871be5ee01ba47d2282
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
ImportanceEarly and accurate diagnosis and treatment of Long COVID, clinically known as post-acute sequelae of COVID-19 (PASC), may mitigate progression to chronic diseases such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Our obje
Externí odkaz:
https://doaj.org/article/580d83ee8267494bad7bd16a2618e5c2
Autor:
Mikail Dogan, Lina Kozhaya, Lindsey Placek, Courtney Gunter, Mesut Yigit, Rachel Hardy, Matthew Plassmeyer, Paige Coatney, Kimberleigh Lillard, Zaheer Bukhari, Michael Kleinberg, Chelsea Hayes, Moshe Arditi, Ellen Klapper, Noah Merin, Bruce Tsan-Tang Liang, Raavi Gupta, Oral Alpan, Derya Unutmaz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Using SARS-CoV-2-specific antibody- and neutralization assays, Dogan et al find that hospitalized individuals show higher IgG antibody responses and higher neutralization titers compared to outpatient or convalescent plasma donors, providing insights
Externí odkaz:
https://doaj.org/article/0a236342fbca4be7ad7450120dc25e6b
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract Objectives Despite advances in antibody treatments and vaccines, COVID‐19 caused by SARS‐CoV‐2 infection remains a major health problem resulting in excessive morbidity and mortality and the emergence of new variants has reduced the ef
Externí odkaz:
https://doaj.org/article/03b8922c2f4b4b9dbac889c8166f8a9f
Autor:
Jihyun Lee, Suzanne D. Vernon, Patricia Jeys, Weam Ali, Andrea Campos, Derya Unutmaz, Brayden Yellman, Lucinda Bateman
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Lightheadedness, fatigue, weakness, heart palpitations, cognitive dysfunction, muscle pain, and exercise intolerance are some of the symptoms of orthostatic intolerance (OI). There is substantial comorbidity of OI in ME/CFS (Myalg
Externí odkaz:
https://doaj.org/article/0dafce6b0896444a9c8474ea831352f2
Autor:
Alan Landay, Jenna M. Bartley, Dishary Banerjee, Geneva Hargis, Laura Haynes, Ali Keshavarzian, Chia-Ling Kuo, Oh Sung Kwon, Sheng Li, Shuzhao Li, Julia Oh, Ibrahim Tarik Ozbolat, Duygu Ucar, Ming Xu, Xudong Yao, Derya Unutmaz, George A. Kuchel
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Aging has emerged as the greatest and most prevalent risk factor for the development of severe COVID-19 infection and death following exposure to the SARS-CoV-2 virus. The presence of multiple coexisting chronic diseases and conditions of aging furth
Externí odkaz:
https://doaj.org/article/ff0ff37f6d9f4409845d2faed7375d79
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Autor:
Didem Saka, Muazzez Gökalp, Betül Piyade, Nedim Can Cevik, Elif Arik Sever, Derya Unutmaz, Güralp O. Ceyhan, Ihsan Ekin Demir, Hande Asimgil
Publikováno v:
Cancers, Vol 12, Iss 8, p 2274 (2020)
T-cell exhaustion is a phenomenon that represents the dysfunctional state of T cells in chronic infections and cancer and is closely associated with poor prognosis in many cancers. The endogenous T-cell immunity and genetically edited cell therapies
Externí odkaz:
https://doaj.org/article/0c60513d8da8417fba139e142232a4c5