Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Derseree. Archary"'
Autor:
Parveen Sobia, Sharana Mahomed, Aida Sivro, Stephane Paul, Farzana Osman, Ishana Harkoo, Nigel Garrett, Quarraisha Abdool Karim, Salim S. Abdool Karim, Derseree Archary
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Acute, transient lymphocytopenia, not clinically significant was observed in the CAPRISA 012B phase 1 clinical trial following administration of broadly neutralizing antibodies (bnAb)-CAP256V2LS alone or with VRC07-523LS. Lymphocytopenia was
Externí odkaz:
https://doaj.org/article/e5979693daf14179af63a736438522fe
Autor:
Thando Glory Maseko, Slindile Ngubane, Marothi Letsoalo, Santhuri Rambaran, Derseree Archary, Natasha Samsunder, Rubeshan Perumal, Surie Chinappa, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Lung cavitation is associated with heightened TB transmission and poor treatment outcomes. This study aimed to determine the relationship between systemic inflammation and lung cavitation in drug-resistant TB patients with and wit
Externí odkaz:
https://doaj.org/article/7afb2dffc19541a3b070195021be452f
Autor:
Santhuri Rambaran, Thando Glory Maseko, Lara Lewis, Razia Hassan-Moosa, Derseree Archary, Sinaye Ngcapu, Nigel Garrett, Lyle R. McKinnon, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Understanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental to disease biomarker discovery, vaccine, and drug development. Using flow cytometry, we chara
Externí odkaz:
https://doaj.org/article/a658362593444ca1815068ef3d1a045a
Autor:
Thando Glory Maseko, Santhuri Rambaran, Slindile Ngubane, Lara Lewis, Sinaye Ngcapu, Razia Hassan-Moosa, Derseree Archary, Rubeshan Perumal, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Natural killer (NK) cells, key effector cells of the innate immune system, play an important role in the clearance and control of Mycobacterium tuberculosis and HIV infections. Here, we utilized peripheral blood specimens from the Improving
Externí odkaz:
https://doaj.org/article/410705ff17ce4b16a4d0c4193c6f43ac
Autor:
Nigel Garrett, Farzana Osman, Sharana Mahomed, Edmund Capparelli, Nonhlanhla Yende Zuma, Derseree Archary, Penny Moore, Natasha Samsunder, Lynn Morris, Salim Abdool Karim, Catherine Hankins, Carolyn Williamson, Bruno Pozzetto, Kevin Carlton, Richard A Koup, Quarraisha Abdool Karim, Leila Mansoor, Tanuja Narayansamy Gengiah, Ishana Harkoo, Precious Radebe, Izukanji T Sikazwe, Disebo Potloane, Nqobile Myeni, Lucio Gama, Sandeep Narpala, Leonid Serebryannyy, Nicole Doria-Rose
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Women-controlled HIV prevention technologies that overcome adherence challenges of available daily oral pre-exposure prophylaxis and give women a choice of options are urgently needed. Broadly neutralising monoclonal antibodies (bnAbs) a
Externí odkaz:
https://doaj.org/article/88fe366c8a104a4da061d0ee7548e10d
Autor:
Noluthando Mazibuko-Motau, Parveen Sobia, Jiawu Xu, Joseph Ahmed Elsherbini, James E. San, Lara Lewis, Andile Mtshali, Gugulethu Mzobe, Lungelo Ntuli, Salim S. Abdool Karim, Leila E. Mansoor, Quarraisha Abdool Karim, Douglas S. Kwon, Derseree Archary, Sinaye Ngcapu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Vaginal microbiota have been shown to be a modifier of protection offered by topical tenofovir in preventing HIV infection in women, an effect not observed with oral tenofovir-based pre-exposure prophylaxis (PrEP). It remains unclear whether
Externí odkaz:
https://doaj.org/article/730844e2c43348088bc74be162787c18
Autor:
Wenkosi Perez Qulu, Gugulethu Mzobe, Andile Mtshali, Marothi Peter Letsoalo, Farzana Osman, James Emmanuel San, Asavela Olona Kama, Nigel Garrett, Adrian Mindel, Anne Rompalo, Lenine J. P. Liebenberg, Derseree Archary, Aida Sivro, Sinaye Ngcapu
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2643 (2023)
Metronidazole (MDZ) treatment failure and bacterial vaginosis (BV) recurrence rates are high among African women. This cohort study identified genital immune parameters associated with treatment response by comparing vaginal microbiota and immune cel
Externí odkaz:
https://doaj.org/article/69ffd93d87ca41f4a6a7c84294b7676a
Autor:
Parveen Sobia, Thevani Pillay, Lenine J. P. Liebenberg, Aida Sivro, Leila E. Mansoor, Farzana Osman, Jo-Ann S. Passmore, Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter, Lyle R. McKinnon, Derseree Archary
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Inflammatory cytokines augment humoral responses by stimulating antibody production and inducing class-switching. In women, genital inflammation (GI) significantly modifies HIV risk. However, the impact of GI on mucosal antibodies remains un
Externí odkaz:
https://doaj.org/article/7093f0217a684180845d9812855678a0
Autor:
Quarraisha Abdool Karim, Derseree Archary, Françoise Barré-Sinoussi, Kristina Broliden, Cecilia Cabrera, Francesca Chiodi, Sarah J. Fidler, Tanuja N. Gengiah, Carolina Herrera, Ayesha B. M. Kharsany, Lenine J. P. Liebenberg, Sharana Mahomed, Elisabeth Menu, Christiane Moog, Gabriella Scarlatti, Nabila Seddiki, Aida Sivro, Mariangela Cavarelli
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Preventing new HIV infections remains a global challenge. Young women continue to bear a disproportionate burden of infection. Oral pre-exposure prophylaxis (PrEP), offers a novel women-initiated prevention technology and PrEP trials completed to dat
Externí odkaz:
https://doaj.org/article/cef9e2df042648619810a33d846c7577
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The use of antiretrovirals (ARVs) as oral, topical, or long-acting pre-exposure prophylaxis (PrEP) has emerged as a promising strategy for HIV prevention. Clinical trials testing Truvada® [tenofovir disoproxil fumarate (TDF)/tenofovir (TFV) and emtr
Externí odkaz:
https://doaj.org/article/66f5a3ab45bc4bf7a50de9b4efe7b055