Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Derry Ridgway"'
Publikováno v:
The Journal of Clinical Pharmacology. 54:1221-1229
Prolongation of the QT interval has been observed with ondansetron and other members of the 5-HT3 antagonist class. This is the first thorough QTc study of ondansetron conducted in accordance with ICH E14 guidelines, designed to investigate the effec
Autor:
Jane Holshouser, Joe Stephenson, Derry Ridgway, Ander Urruticoechea Ribate, Kevin M. Koch, Jeffrey Botbyl, Sung Bae Kim, Leanne Cartee, Young-Hyuck Im
Publikováno v:
Clinical Pharmacology in Drug Development. 2:336-341
The aqueous solubility of lapatinib declines significantly at pH >4, suggesting that its bioavailability might be lowered by acid-reducing drugs. A study was therefore conducted to assess the effects of esomeprazole on lapatinib pharmacokinetics (PK)
Autor:
Derry Ridgway, Carolyn Ridgway
Publikováno v:
Teaching Statistics. 32:34-40
Summary Using sequences of coin flips as a model of serial independent events, we asked schoolchildren in grades 1 through 5 to estimate the likelihood of the next flip. Most children in each grade expected short patterns to continue.
Publikováno v:
Journal of Pain and Symptom Management. 39:712-720
Context Recently, a new oral prolonged-release formulation of morphine sulfate for once-daily dosing has been developed based on an injection-molded matrix (abuse-deterrent, prolonged-release erodible matrix [ADPREM]). Objectives The objective of thi
Publikováno v:
Drug Information Journal. 41:701-708
Few investigations have compared placebo group outcomes across therapeutic areas. We examined placebo group outcomes from 171 clinical trials reported in the Food and Drug Administration (FDA) Summary Basis of Approvals describing 33 medications for
Publikováno v:
Biological Psychiatry. 62:65-71
Background We assessed whether increasing the minimum prerandomization Hamilton Depression Rating Scale (HAM-D) score to enrich the severity of the depressed sample affects antidepressant trial outcome. Methods Using the Food and Drug Administration
Autor:
Derry Ridgway
Publikováno v:
The Clinical Journal of Pain. 20:123-132
Objective To examine the United States Food and Drug Administration's (FDA) standards for reviews of the scientific basis for efficacy claims for newly approved oral analgesics. Methods Comparison of the trial methodologies and results provided by th
Autor:
Derry Ridgway
Publikováno v:
Journal of Health Politics, Policy and Law. 24:59-90
During the first eight years of the National Vaccine Injury Compensation Program (NVICP), 786 contested claims were resolved through published judicial opinions. The likelihood of compensation depended in part on the closeness of the match between th
Autor:
Kevin M, Koch, Young-Hyuck, Im, Sung-Bae, Kim, Ander, Urruticoechea Ribate, Joe, Stephenson, Jeffrey, Botbyl, Leanne, Cartee, Jane, Holshouser, Derry, Ridgway
Publikováno v:
Clinical pharmacology in drug development. 2(4)
The aqueous solubility of lapatinib declines significantly at pH4, suggesting that its bioavailability might be lowered by acid-reducing drugs. A study was therefore conducted to assess the effects of esomeprazole on lapatinib pharmacokinetics (PK).
Autor:
Lawrence J. Wolff, Derry Ridgway
Publikováno v:
Leukemia & Lymphoma. 9:177-192
Active immunization against measles, Haemophilus influenza B, tetanus, diphtheria, hepatitis B, influenza, poliomyelitis, and, when indicated varicella and pneumococcus induces long-lasting immunologic protection in most healthy pediatric vaccine rec