Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Derry C. Roopenian"'
Autor:
John J. Wilson, Jian Wei, Andrea R. Daamen, John D. Sears, Elaine Bechtel, Colleen L. Mayberry, Grace A. Stafford, Lesley Bechtold, Amrie C. Grammer, Peter E. Lipsky, Derry C. Roopenian, Chih-Hao Chang
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107487- (2023)
Summary: Aberrant metabolic demand is observed in immune/inflammatory disorders, yet the role in pathogenesis remains unclear. Here, we discover that in lupus, activated B cells, including germinal center B (GCB) cells, have remarkably high glycolyti
Externí odkaz:
https://doaj.org/article/e7ca57bc1ffa4a2dbdc80de127fb14a9
Autor:
Thomas J. Sproule, Robert Y. Wilpan, John J. Wilson, Benjamin E. Low, Yudai Kabata, Tatsuo Ushiki, Riichiro Abe, Michael V. Wiles, Derry C. Roopenian, John P. Sundberg
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/bb36004a0e2244fc95afb205ce007495
Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice
Autor:
Thomas J. Sproule, Robert Y. Wilpan, Benjamin E. Low, Kathleen A. Silva, Deepak Reyon, J. Keith Joung, Michael V. Wiles, Derry C. Roopenian, John P. Sundberg
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/b35e2867765f469386053944e0c11913
Autor:
Seung-Chul Choi, Anton A. Titov, Georges Abboud, Howard R. Seay, Todd M. Brusko, Derry C. Roopenian, Shahram Salek-Ardakani, Laurence Morel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
T cell functions depend on distinct metabolic fluxes. Here the authors show different metabolic requirements of humoral responses to self versus microbial antigens: while glucose is dispensable for antiviral Tfh and antibody responses, it is essentia
Externí odkaz:
https://doaj.org/article/3e0a1f8d30674ceda6619fa064e835de
Autor:
Algirdas Grevys, Jeannette Nilsen, Kine M. K. Sand, Muluneh B. Daba, Inger Øynebråten, Malin Bern, Martin B. McAdam, Stian Foss, Tilman Schlothauer, Terje E. Michaelsen, Gregory J. Christianson, Derry C. Roopenian, Richard S. Blumberg, Inger Sandlie, Jan Terje Andersen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The development of IgG and albumin-based therapeutics with increased half-lives needs more efficient screening procedures. Here the authors report a human endothelial cell-based recycling assay enabling screening of IgG and albumin variants without c
Externí odkaz:
https://doaj.org/article/99bc76e2016a473a870d99a7c561cd47
Autor:
Elisabeth A. Marnik, Xulong Wang, Thomas J. Sproule, Giljun Park, Gregory J. Christianson, Sarah Kate Lane-Reticker, Shweta Jain, Theodore Duffy, Hongsheng Wang, Gregory W. Carter, Herbert C. Morse, III, Derry C. Roopenian
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 208-221 (2017)
Interleukin 21 (IL-21) plays key roles in humoral immunity and autoimmune diseases. It is known to function in mature CD4+ T follicular B cell helper (TFH) cells, but its potential involvement in early T cell ontogeny is unclear. Here, we find that a
Externí odkaz:
https://doaj.org/article/8c5c925b9a49414d868f8ea10c5e174b
Autor:
Georges Abboud, Seung-Chul Choi, Nathalie Kanda, Leilani Zeumer-Spataro, Derry C. Roopenian, Laurence Morel
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The K/BxN mouse is a spontaneous model of arthritis driven by T cell receptor transgenic CD4+ T cells from the KRN strain that are activated by glucose-6-phosphate isomerase (GPI) peptides presented by the H-2g7 allele from the NOD strain. It is a mo
Externí odkaz:
https://doaj.org/article/501e311affa74ece8b53b2a9f0566959
Publikováno v:
Interdisciplinary Perspectives on Infectious Diseases, Vol 2009 (2009)
Periodontal disease is one of the most common infectious diseases of humans. Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. We investigated the contribution of B cell IgD to alveolar bone loss by com
Externí odkaz:
https://doaj.org/article/117309d489bc43448ae3e05fff177107
Supplementary Table 2 from NOTCH Is Part of the Transcriptional Network Regulating Cell Growth and Survival in Mouse Plasmacytomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5e62b5886e181492e5c17da0e628fc
https://doi.org/10.1158/0008-5472.22373621.v1
https://doi.org/10.1158/0008-5472.22373621.v1
Autor:
Herbert C. Morse, Siegfried Janz, Wendy F. Davidson, Derry C. Roopenian, Janet W. Hartley, Torgny N. Fredrickson, Alexander L. Kovalchuk, Shao Xiang, Zohreh Naghashfar, Chang Hoon Lee, Jeff X. Zhou, Chen-Feng Qi
Supplementary Data 1 from Anaplastic, Plasmablastic, and Plasmacytic Plasmacytomas of Mice: Relationships to Human Plasma Cell Neoplasms and Late-Stage Differentiation of Normal B Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4249f8ff606fdf14c6e44979fd6627be
https://doi.org/10.1158/0008-5472.22366748.v1
https://doi.org/10.1158/0008-5472.22366748.v1