Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Derrick Zhao"'
Autor:
Yanyan Wang, Derrick Zhao, Lianyong Su, Yun-Ling Tai, Grayson W. Way, Jing Zeng, Qianhua Yan, Ying Xu, Xuan Wang, Emily C. Gurley, Xi-Qiao Zhou, Jinze Liu, Jinpeng Liu, Weidong Chen, Phillip B. Hylemon, Huiping Zhou
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Background and aims Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by progressive biliary inflammation and bile duct injury. Berberine (BBR) is a bioactive isoquinoline alkaloid found in various herbs and has m
Externí odkaz:
https://doaj.org/article/c40cee7852b64c49988c83b99ea9710b
Autor:
Jennifer T. Wolstenholme, Justin M. Saunders, Maren Smith, Jason D. Kang, Phillip B. Hylemon, Javier González-Maeso, Andrew Fagan, Derrick Zhao, Masoumeh Sikaroodi, Jeremy Herzog, Amirhossein Shamsaddini, Marcela Peña-Rodríguez, Lianyong Su, Yun-Ling Tai, Jing Zheng, Po-Cheng Cheng, R. Balfour Sartor, Patrick M. Gillevet, Huiping Zhou, Jasmohan S. Bajaj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Gut microbiota composition is altered in patients with alcohol use disorder, and fecal microbiota transplant reduced alcohol craving in patients with alcohol use disorder and liver cirrhosis in a phase 1 clinical trial. Here the authors used stool sa
Externí odkaz:
https://doaj.org/article/71cd530afe02445e92a5c780310d4264
Autor:
Yanyan Wang, Yun-Ling Tai, Grayson Way, Jing Zeng, Derrick Zhao, Lianyong Su, Xixian Jiang, Kaitlyn G. Jackson, Xuan Wang, Emily C. Gurley, Jinze Liu, Jinpeng Liu, Weidong Chen, Xiang-Yang Wang, Arun J. Sanyal, Phillip B. Hylemon, Huiping Zhou
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Background NAFLD has become the most common chronic liver disease worldwide. Human antigen R (HuR), an RNA-binding protein, is an important post-transcriptional regulator. HuR has been reported as a key player in regulating lipid homeostasis
Externí odkaz:
https://doaj.org/article/d84759287cdb4599b7709d2778b2a56b
Autor:
Yuan Zhang, Jason D. Kang, Derrick Zhao, Siddartha S. Ghosh, Yanyan Wang, Yunling Tai, Javier Gonzalez-Maeso, Masoumeh Sikaroodi, Patrick M. Gillevet, H. Robert Lippman, Phillip B. Hylemon, Huiping Zhou, Jasmohan S. Bajaj
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundCirrhosis and hepatic encephalopathy (HE) are linked with an altered gut-liver-brain axis, however, the relative contribution of hepatic vagal innervation is unclear. We aimed to determine the impact of hepatic vagotomy on the gut microbiom
Externí odkaz:
https://doaj.org/article/88a0eab8c12b4e55977c23ab76ba90da
Autor:
Yanyan Wang, Xiqiao Zhou, Derrick Zhao, Xuan Wang, Emily C Gurley, Runping Liu, Xiaojiaoyang Li, Phillip B Hylemon, Weidong Chen, Huiping Zhou
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232630 (2020)
Inflammation plays an essential role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Berberine (BBR), an isoquinoline alkaloid isolated from Chinese medicinal herbs, has been widely used to treat various diseases, including liver di
Externí odkaz:
https://doaj.org/article/79e26f179ae04c5c936faf410f948ef3
Autor:
Rui Xue, Lianyong Su, Shengyi Lai, Yanyan Wang, Derrick Zhao, Jiangao Fan, Weidong Chen, Phillip B. Hylemon, Huiping Zhou
Publikováno v:
Cells, Vol 10, Iss 11, p 2806 (2021)
The prevalence of nonalcoholic fatty liver disease (NAFLD) has been significantly increased due to the global epidemic of obesity. The disease progression from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH) is closely linked to inflam
Externí odkaz:
https://doaj.org/article/d7694d2bc7f14f18a0a127caecc01430
Autor:
Jing Zeng, Derrick Zhao, Yun-ling Tai, Xixian Jiang, Lianyong Su, Xuan Wang, Emily Gurley, Phillip B. Hylemon, Jiangao Fan, Sayed Obaidullah Ase, Arun J. Sanyal, Huiping Zhou
Publikováno v:
Physiology. 38
Background: Nonalcoholic fatty liver disease (NAFLD) is the fastest-rising cause of end-stage liver disease for liver transplantation. The underlying mechanisms of NAFLD disease progression from nonalcoholic steatohepatitis (NASH) to hepatocellular c
Autor:
Yanyan Wang, Yun-Ling Tai, Derrick Zhao, Yuan Zhang, Junkai Yan, Genta Kakiyama, Xuan Wang, Emily C. Gurley, Jinze Liu, Jinpeng Liu, Jimin Liu, Guanhua Lai, Phillip B. Hylemon, William M. Pandak, Weidong Chen, Huiping Zhou
Publikováno v:
Cells, Vol 10, Iss 2, p 210 (2021)
Background and Aims: The disease progression of nonalcoholic fatty liver disease (NAFLD) from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH) is driven by multiple factors. Berberine (BBR) is an ancient Chinese medicine and has various
Externí odkaz:
https://doaj.org/article/196a8eaf79bc4c698900c2d12f6a79c8
Autor:
Xiaojiaoyang Li, Runping Liu, Yanyan Wang, Weiwei Zhu, Derrick Zhao, Xuan Wang, Hang Yang, Emily C. Gurley, Weidong Chen, Phillip B. Hylemon, Huiping Zhou
Publikováno v:
Cells, Vol 9, Iss 1, p 190 (2020)
Activation of hepatic macrophages represents the critical driving force to promote cholestatic liver injury. Exosomes, as important small extracellular vesicles released by almost all types of cells, contribute to intercellular communication. We prev
Externí odkaz:
https://doaj.org/article/730d4358473244fab7c00b27df41d3b4
Autor:
Jasmohan S. Bajaj, Yunling Tai, Derrick Zhao, Phillip B. Hylemon, Javier González-Maeso, Yanyan Wang, Huiping Zhou, H. Robert Lippman, Masoumeh Sikaroodi, Jason D. Kang, Yuan Zhang, Siddartha S Ghosh, Patrick M. Gillevet
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
BackgroundCirrhosis and hepatic encephalopathy (HE) are linked with an altered gut-liver-brain axis, however, the relative contribution of hepatic vagal innervation is unclear. We aimed to determine the impact of hepatic vagotomy on the gut microbiom