Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Derrick W. Meinhold"'
Publikováno v:
The Journal of Physical Chemistry B. 126:9539-9548
The earliest events in the folding of a protein are in general poorly understood. We used NMR
Autor:
Yong Jiang, Tia Lewis, Patricia M. McCormick, Michael Schaber, Beth Pietrak, Rachel D. Totoritis, Marc A. Holbert, Lawrence M. Szewczuk, Daniel Fornwald, William G. Bonnette, Geoffrey Quinque, Maggie Grimes, Rosalie E. Matico, Ed Dul, Randy K. Bledsoe, Derrick W. Meinhold, Stephanie Chen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Significant resource is spent by drug discovery project teams to generate numerous, yet unique target constructs for the multiple platforms used to drive drug discovery programs including: functional assays, biophysical studies, structural biology, a
Abstract 2919: Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen
Autor:
Stuart Paul Romeril, Gopinath Ganji, Dirk A. Heerding, George P. Livi, Anna Rutkowska-Klute, William Hoi Hong Li, James F. Mack, Elisabeth A. Minthorn, Derrick W. Meinhold, Carolyn A. Buser, Jesus R. Medina, Lorena A. Kallal, Shanker K. Sundaram, Biju Mangatt, Anthony Della Pietra, Sonja Ghidelli-Disse, Anna Waszkiewicz, Jon-Paul Jaworski, Thomas J. Berrodin, Rakesh Kumar, Wendy S. Halsey, Christian S. Sherk, Gerard Drewes
Publikováno v:
Cancer Research. 78:2919-2919
Elevated expression of the c-MYC oncogene (either due to gene amplification, translocation, abnormality in upstream signaling pathways and/or protein stabilization) is one of the most common abnormalities in human cancers. Efforts to identify direct
Publikováno v:
Biochemistry. 41:13744-13754
Factor for inversion stimulation (FIS) is a 22 kDa homodimeric protein found in enteric bacteria that is involved in the stimulation of certain DNA recombination events and transcription regulation of many genes. FIS has a central helix with a 20 deg
Autor:
Peter E. Wright, Derrick W. Meinhold
Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use 15 N, , and 13 CO NMR R 2 relaxation dispersion to investigate spontaneous un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83e9b78b59e53a5c0bb0443f91dc2e
https://europepmc.org/articles/PMC3107309/
https://europepmc.org/articles/PMC3107309/