Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Derrick R, Robinson"'
Autor:
Chloé Roumégous, Aya Abou Hammoud, Damien Fuster, Jean-William Dupuy, Corinne Blancard, Bénédicte Salin, Derrick R. Robinson, Patricia Renesto, Isabelle Tardieux, Karine Frénal
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The Toxoplasma gondii tachyzoite is a singled-cell obligate intracellular parasite responsible for the acute phase of toxoplasmosis. This polarized cell exhibits an apical complex, a hallmark of the phylum Apicomplexa, essential for motility, invasio
Externí odkaz:
https://doaj.org/article/15f7f81144034ac3a66f188beb070141
Autor:
Christine E. Broster Reix, Miharisoa Rijatiana Ramanantsalama, Carmelo Di Primo, Laëtitia Minder, Mélanie Bonhivers, Denis Dacheux, Derrick R. Robinson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Trypanosoma brucei belongs to a genus of protists that cause life-threatening and economically important diseases of human and animal populations in Sub-Saharan Africa. T. brucei cells are covered in surface glycoproteins, some of which are
Externí odkaz:
https://doaj.org/article/3483f07dcfb4435c85695897cfdd9cf6
Autor:
Charlotte Isch, Paul Majneri, Nicolas Landrein, Yulia Pivovarova, Johannes Lesigang, Florian Lauruol, Derrick R Robinson, Gang Dong, Mélanie Bonhivers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009329 (2021)
The flagellar pocket (FP) is the only endo- and exocytic organelle in most trypanosomes and, as such, is essential throughout the life cycle of the parasite. The neck of the FP is maintained enclosed around the flagellum via the flagellar pocket coll
Externí odkaz:
https://doaj.org/article/342552844d3f4eaabbb926a00273446c
Autor:
Rosa Milagros Corrales, Slavica Vaselek, Rachel Neish, Laurence Berry, Camille D Brunet, Lucien Crobu, Nada Kuk, Julio Mateos-Langerak, Derrick R Robinson, Petr Volf, Jeremy C Mottram, Yvon Sterkers, Patrick Bastien
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009666 (2021)
Leishmania parasites possess a unique and complex cytoskeletal structure termed flagellum attachment zone (FAZ) connecting the base of the flagellum to one side of the flagellar pocket (FP), an invagination of the cell body membrane and the sole site
Externí odkaz:
https://doaj.org/article/0f2c6b9c7f12491a96936e7b139ee155
Autor:
Emma Stepinac, Nicolas Landrein, Daria Skwarzyńska, Patrycja Wójcik, Johannes Lesigang, Iva Lučić, Cynthia Y. He, Mélanie Bonhivers, Derrick R. Robinson, Gang Dong
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102422- (2021)
Summary: Extended synaptotagmins (E-Syts) localize at membrane contact sites between the endoplasmic reticulum (ER) and the plasma membrane to mediate inter-membrane lipid transfer and control plasma membrane lipid homeostasis. All known E-Syts conta
Externí odkaz:
https://doaj.org/article/2cd4a1bc3662459395d9553da56a500c
Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human
Autor:
Charles Coutton, Alexandra S. Vargas, Amir Amiri-Yekta, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Pauline Le Tanno, Clémentine Wambergue-Legrand, Thomas Karaouzène, Guillaume Martinez, Serge Crouzy, Abbas Daneshipour, Seyedeh Hanieh Hosseini, Valérie Mitchell, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Jean-François Deleuze, Anne Boland, Sylviane Hennebicq, Véronique Satre, Pierre-Simon Jouk, Nicolas Thierry-Mieg, Beatrice Conne, Denis Dacheux, Nicolas Landrein, Alain Schmitt, Laurence Stouvenel, Patrick Lorès, Elma El Khouri, Serge P. Bottari, Julien Fauré, Jean-Philippe Wolf, Karin Pernet-Gallay, Jessica Escoffier, Hamid Gourabi, Derrick R. Robinson, Serge Nef, Emmanuel Dulioust, Raoudha Zouari, Mélanie Bonhivers, Aminata Touré, Christophe Arnoult, Pierre F. Ray
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Asthenozoospermia is a major cause of male infertility, and multiple morphological abnormalities of the flagella (MMAF) is a particularly severe form. Here, using whole-exome sequencing of 78 MMAF patients, the authors identify mutations in two WDR p
Externí odkaz:
https://doaj.org/article/03b883f351d94cb6999191bf43221e62
Autor:
Christine E. Broster Reix, Célia Florimond, Anne Cayrel, Amélie Mailhé, Corentin Agnero-Rigot, Nicolas Landrein, Denis Dacheux, Katharina Havlicek, Mélanie Bonhivers, Brooke Morriswood, Derrick R. Robinson
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2334 (2021)
Background: In most trypanosomes, endo and exocytosis only occur at a unique organelle called the flagellar pocket (FP) and the flagellum exits the cell via the FP. Investigations of essential cytoskeleton-associated structures located at this site h
Externí odkaz:
https://doaj.org/article/af2f51dfb5f1471ba8c85b0ce0261886
Autor:
Balázs Szöőr, Dorina V. Simon, Federico Rojas, Julie Young, Derrick R. Robinson, Timothy Krüger, Markus Engstler, Keith R. Matthews
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Glycosomes are peroxisome-related organelles that compartmentalize the glycolytic enzymes in kinetoplastid parasites. These organelles are developmentally regulated in their number and composition, allowing metabolic adaptation to the parasi
Externí odkaz:
https://doaj.org/article/db74b9b8f9794d29b042d9f4235b3304
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 4, p e0007264 (2019)
Trypanosomatids are flagellated protozoan parasites that are very unusual in terms of cytoskeleton organization but also in terms of cell death. Most of the Trypanosomatid cytoskeleton consists of microtubules, forming different substructures includi
Externí odkaz:
https://doaj.org/article/0eff427a0f38431bad2d676718ccfd0f
Autor:
Denis Dacheux, Guillaume Martinez, Christine E. Broster Reix, Julie Beurois, Patrick Lorès, Magamba Tounkara, Jean-William Dupuy, Derrick R. Robinson, Corinne Loeuillet, Emeline Lambert, Zeina Wehbe, Amir Amiri-Yekta, Abbas Daneshipour, Seyedeh-Hanieh Hosseini, Raoudha Zouari, Sélima Fourati Ben Mustapha, Lazhar Halouani, Xiaohui Jiang, Ying Shen, Chunyu Liu, Nicolas Thierry-Mieg, Amandine Septier, Marie Bidart, Véronique Satre, Caroline Cazin, Zine-Eddine Kherraf, Christophe Arnoult, Pierre F. Ray, Aminata Touré, Mélanie Bonhivers, Charles Coutton
Male infertility is common and complex, presenting a wide range of heterogeneous phenotypes. Although about 50% of cases are estimated to have a genetic component, the underlying cause often remains undetermined. Here, from whole-exome sequencing on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b352644612446834dc364617a453b56d
https://doi.org/10.1101/2023.03.07.531490
https://doi.org/10.1101/2023.03.07.531490
