Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Derrick L. Domingo"'
Autor:
S. Maxwell, Clare E. Futter, Derrick L. Domingo, Ian S. Trowbridge, E.H. Allchin, L.J. Ruddock, Colin R. Hopkins, Greg Odorizzi, Adele Gibson
Publikováno v:
The Journal of Cell Biology
Human transferrin receptors (TR) and receptors for polymeric immunoglobulins (pIgR) expressed in polarized MDCK cells maintain steady-state, asymmetric distributions on the separate basolateral and apical surfaces even though they are trafficking con
Autor:
Derrick L. Domingo, E.H. Allchin, Adele Gibson, Colin R. Hopkins, Mark Shipman, Clare E. Futter, Greg Odorizzi, Ian S. Trowbridge, S. Maxwell, J.-P. Kraehenbuhl
Publikováno v:
The Journal of cell biology, vol. 143, no. 1, pp. 81-94
The Journal of Cell Biology
The Journal of Cell Biology
The transcytotic pathway followed by the polymeric IgA receptor (pIgR) carrying its bound ligand (dIgA) from the basolateral to the apical surface of polarized MDCK cells has been mapped using morphological tracers. At 20°C dIgA-pIgR internalize to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739050d9fec0b796eed2744e30be51c
https://serval.unil.ch/resource/serval:BIB_3EBEBE83249A.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_3EBEBE83249A.P001/REF.pdf
Publikováno v:
The Journal of Cell Biology
We have evaluated transcytotic routes in MDCK cells for their ability to generate a polarized surface distribution of trafficking proteins by following the intracellular sorting of transferrin receptors (TRs). We find that the selective basolateral e
Publikováno v:
Biochemical Pharmacology. 33:925-932
Autor:
Derrick L. Domingo, Ian S. Trowbridge
Publikováno v:
Nature. 294:171-173
The development of the monoclonal antibody technique1 has led to renewed interest in whether the growth of tumour cells may be specifically inhibited by antibodies or antibody–toxin conjugates directed against antigenic determinants selectively exp
Publikováno v:
Nature. 304(5927)
Transferrin receptors are expressed in large quantities on tissues with high requirements for iron such as maturing erythroid cells and placenta. In addition, they are found in abundance on proliferating cells from other normal tissues1–5 as well a
Autor:
Ian S. Trowbridge, Derrick L. Domingo
Publisher Summary This chapter describes the preparation and properties of antibody–ricin A conjugates that are specific for the transferrin receptors of human and murine cells. Ricin A-chain–antibody conjugates are prepared using the cross-linki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d626363415c66184e4bf058d935a1148
https://doi.org/10.1016/s0076-6879(85)12020-3
https://doi.org/10.1016/s0076-6879(85)12020-3
Autor:
Jayne Lesley, Derrick L. Domingo, Carol A. Sauvage, Roberta Schulte, Ian S. Trowbridge, Hans-Georg Rammensee
Publikováno v:
Peptide Growth Factors-Part B ISBN: 9780121820473
Publisher Summary This chapter describes the derivation of monoclonal antibodies against the transferrin receptor and assay of their biological effects. Antibodies that block receptor function have proved to be useful in dissecting the role of transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc32a1c827708de6450ddcde48dc9b6
https://doi.org/10.1016/0076-6879(87)47117-6
https://doi.org/10.1016/0076-6879(87)47117-6
Publikováno v:
Experimental cell research. 150(2)
A monoclonal antibody with specificity for murine transferrin receptor was conjugated with the toxic A subunit of ricin. The dose range, specificity, and kinetics of inhibition of protein synthesis of the conjugate were determined on the murine T-lym