Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Derrick D. Goodman"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:3441-3449
The most common pattern of emergent resistance in the phase III clinical trials of coformulated elvitegravir (EVG)-cobicistat (COBI)-emtricitabine (FTC)-tenofovir disoproxil fumarate (TDF) was the EVG resistance substitution E92Q in integrase (IN) wi
Autor:
Katyna Borroto-Esoda, Damian J McColl, Nicolas A. Margot, Evguenia S. Svarovskaia, Michael D. Miller, Lijie Zhong, Yun Zhou, Derrick D. Goodman
Publikováno v:
AIDS. 25:325-333
BACKGROUND Study GS-01-934 was a randomized open-label phase III study comparing efavirenz and tenofovir/emtricitabine to efavirenz and zidovudine/lamivudine in treatment-naive HIV-1-infected individuals. Through 144 weeks, 50 of 487 participants wit
Autor:
Andrew Bae, Katyna Borroto-Esoda, Lijie Zhong, Nicolas A. Margot, Evguenia S. Svarovskaia, Derrick D. Goodman, Michael D. Miller, Joshua M. Waters
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 46:174-180
Background: Prior abacavir (ABC) or didanosine (ddI) therapy can result in the L74V/I or K65R mutation in HIV-1 reverse transcriptase. Preexisting K65R may have an impact on the treatment response to tenofovir disoproxil fumarate (TDF). Methods: An a
Autor:
Karin S. Ku, Evguenia S. Svarovskaia, Andrew Bae, Derrick D. Goodman, Hongmei Mo, Michael D. Miller
Publikováno v:
Journal of Antivirals & Antiretrovirals.
Tegobuvir (GSâ9190) is a novel hepatitis C virus (HCV) nonânucleoside NS5B polymerase inhibitor that effectively inhibits HCV replication in HCV-infected genotype (GT) 1 patients. The NS5B Y448H mutation was the most frequent mutation selec
Autor:
Evguenia S. Svarovskaia, Joy Y. Feng, Derrick D. Goodman, Florence Myrick, Michael D. Miller, John K Ly, Katyna Borroto-Esoda, Kirsten L. White
Publikováno v:
Retrovirology, Vol 6, Iss 1, p 44 (2009)
Retrovirology
Retrovirology
Background Tenofovir disoproxil fumarate (TDF), emtricitabine (FTC), and efavirenz (EFV) are the three components of the once-daily, single tablet regimen (Atripla) for treatment of HIV-1 infection. Previous cell culture studies have demonstrated tha
Autor:
Joy Y. Feng, Nilima Kutty, Katyna Borroto-Esoda, Florence Myrick, Nicolas A. Margot, John K Ly, Evguenia S. Svarovskaia, Ruth Wang, Derrick D. Goodman, Kirsten L. White, Michael D. Miller
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 48(4)
Background: The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase can be selected by abacavir, didanosine, tenofovir, and stavudine in vivo resulting in reduced susceptibility to these drugs and decreased viral replication ca