Real-world survival outcomes in patients with locally advanced or metastatic NTRK fusion-positive solid tumors receiving standard-of-care therapies other than targeted TRK inhibitors.

Autor: Derrek P Hibar, George D Demetri, Solange Peters, Jessica Davies, Olivier Humblet, Sophia L Maund, Laura Perez

Publikováno v: PLoS ONE, Vol 17, Iss 8, p e0270571 (2022)

The clinical profiles and outcomes of patients with neurotrophic tropomyosin receptor kinase fusion-positive (NTRK+) solid tumors receiving standard of care other than tropomyosin receptor kinase inhibitor (TRKi) targeted therapy have not been well d

Externí odkaz: https://doaj.org/article/2e5ab741774341bbb06e5432de925044

Discovery and replication of gene influences on brain structure using LASSO regression

Autor: Omid eKohannim, Derrek P Hibar, Jason L Stein, Neda eJahanshad, Xue eHua, Priya eRajagopalan, Art eToga, Clifford R Jack Jr, Michael W Weiner, Greig I de Zubicaray, Katie L McMahon, Narelle K Hansell, Nicholas G Martin, Margaret J Wright, Paul M Thompson

Publikováno v: Frontiers in Neuroscience, Vol 6 (2012)

We implemented LASSO (least absolute shrinkage and selection operator) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part

Externí odkaz: https://doaj.org/article/b7e94a06728146e292b1fd816a4e80be

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Autor: Edith Hofer, Gennady V. Roshchupkin, Hieab H. H. Adams, Maria J. Knol, Honghuang Lin, Shuo Li, Habil Zare, Shahzad Ahmad, Nicola J. Armstrong, Claudia L. Satizabal, Manon Bernard, Joshua C. Bis, Nathan A. Gillespie, Michelle Luciano, Aniket Mishra, Markus Scholz, Alexander Teumer, Rui Xia, Xueqiu Jian, Thomas H. Mosley, Yasaman Saba, Lukas Pirpamer, Stephan Seiler, James T. Becker, Owen Carmichael, Jerome I. Rotter, Bruce M. Psaty, Oscar L. Lopez, Najaf Amin, Sven J. van der Lee, Qiong Yang, Jayandra J. Himali, Pauline Maillard, Alexa S. Beiser, Charles DeCarli, Sherif Karama, Lindsay Lewis, Mat Harris, Mark E. Bastin, Ian J. Deary, A. Veronica Witte, Frauke Beyer, Markus Loeffler, Karen A. Mather, Peter R. Schofield, Anbupalam Thalamuthu, John B. Kwok, Margaret J. Wright, David Ames, Julian Trollor, Jiyang Jiang, Henry Brodaty, Wei Wen, Meike W. Vernooij, Albert Hofman, André G. Uitterlinden, Wiro J. Niessen, Katharina Wittfeld, Robin Bülow, Uwe Völker, Zdenka Pausova, G. Bruce Pike, Sophie Maingault, Fabrice Crivello, Christophe Tzourio, Philippe Amouyel, Bernard Mazoyer, Michael C. Neale, Carol E. Franz, Michael J. Lyons, Matthew S. Panizzon, Ole A. Andreassen, Anders M. Dale, Mark Logue, Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro-Conde, Janita Bralten, Derrek P. Hibar, Penelope A. Lind, Fabrizio Pizzagalli, Jason L. Stein, Paul M. Thompson, Sarah E. Medland, ENIGMA consortium, Perminder S. Sachdev, William S. Kremen, Joanna M. Wardlaw, Arno Villringer, Cornelia M. van Duijn, Hans J. Grabe, William T. Longstreth, Myriam Fornage, Tomas Paus, Stephanie Debette, M. Arfan Ikram, Helena Schmidt, Reinhold Schmidt, Sudha Seshadri

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Cortex morphology varies with age, cognitive function, and in neurological and psychiatric diseases. Here the authors report 160 genome-wide significant associations with thickness, surface area and volume of the total cortex and 34 cortical regions

Externí odkaz: https://doaj.org/article/5d16e85f224b486f9cfab04f0d940bed

Cortical thickness across the lifespan

Autor: Simon E. Fisher, Eveline A. Crone, Dominik Grotegerd, Jilly Naaijen, Anders M. Dale, Sean N. Hatton, Ramona Baur-Streubel, Anthony A. James, Daniel Brandeis, Andrew J. Kalnin, Andreas Reif, Hans-Jörgen Grabe, Pieter J. Hoekstra, Lars Nyberg, Fleur M. Howells, Moji Aghajani, Randy L. Buckner, Daniel A. Rinker, Steven G. Potkin, Dennis van 't Ent, Rachel M. Brouwer, Sophia Frangou, Yang Wang, Nhat Trung Doan, Theodore D. Satterthwaite, Christine Lochner, Geraldo F. Busatto, Lars T. Westlye, Lara M. Wierenga, Calhoun Vd, Henry Brodaty, Carles Soriano-Mas, Annette Conzelmann, Christian K. Tamnes, Julian N. Trollor, Nicholas G. Martin, Neeltje E.M. van Haren, René S. Kahn, Irina Lebedeva, Philip Asherson, Suzanne C. Swagerman, John A. Joska, Theophilus N. Akudjedu, Kang Sim, Lachlan T. Strike, Patricia Gruner, Brenna C. McDonald, Thomas Frodl, Edith Pomarol-Clotet, Víctor Ortiz-García de la Foz, Margaret J. Wright, Norbert Hosten, Jean-Paul Fouche, Bernd Weber, Salvador Sarró, Wei Wen, Dag Alnæs, Greig I. de Zubicaray, Iris E. C. Sommer, Marise W. J. Machielsen, Knut Schnell, Dara M. Cannon, Paola Fuentes-Claramonte, Josiane Bourque, Andreas Meyer-Lindenberg, Anton Albajes-Eizagirre, Sarah Hohmann, Erin W. Dickie, Theo G.M. van Erp, Micael Andersson, Paul Pauli, Thomas Espeseth, Heather C. Whalley, Victoria Chubar, Ruben C. Gur, Tomohiro Nakao, Xavier Caseras, Alessandro Bertolino, Ignacio Martínez-Zalacaín, Katharina Wittfeld, Erick J. Canales-Rodríguez, David C. Glahn, Neda Jahanshad, Jiyang Jiang, Katie L. McMahon, Stefan Borgwardt, Erlend S. Dørum, Jaap Oosterlaan, Won Hee Lee, Alan Breier, Steven Williams, Aristotle N. Voineskos, Bernard Mazoyer, Jordan W. Smoller, Nancy C. Andreasen, Ilya M. Veer, Tiffany M. Chaim-Avancini, Sophie Maingault, Paul M. Thompson, Eco J. C. de Geus, Luisa Lázaro, Giulio Pergola, Efstathios Papachristou, Beng-Choon Ho, David Mataix-Cols, Esther Walton, Ben J. Harrison, Dirk J. Heslenfeld, Pablo Najt, Helena Fatouros-Bergman, Derrek P. Hibar, Gunter Schumann, Raymond Salvador, Lieuwe de Haan, Henry Völzke, Joaquim Radua, Henk Temmingh, Lianne Schmaal, Martine Hoogman, Daniel H. Wolf, Georg C. Ziegler, Marieke Klein, Barbara Franke, Erik G. Jönsson, Laura Koenders, Stefan Ehrlich, Oliver Gruber, Ingrid Agartz, Kun Yang, Ryota Kanai, Sarah Baumeister, Colm McDonald, Annabella Di Giorgio, Amanda Worker, Anne Uhlmann, Marcus V. Zanetti, Danai Dima, Matthew D. Sacchet, Sarah E. Medland, Aurora Bonvino, Benedicto Crespo-Facorro, Jan Egil Nordvik, Joshua L. Roffman, Yannis Paloyelis, Jessica A. Turner, T. P. Klyushnik, Christopher G. Davey, Rachel E. Gur, Ian B. Hickie, Christopher R.K. Ching, Jonna Kuntsi, Tobias Banaschewski, Chaim Huyser, Amirhossein Modabbernia, John D. West, Fabrice Crivello, Núria Bargalló, Patricia J. Conrod, Nic J.A. van der Wee, Mauricio H. Serpa, Thomas H. Wassink, Kathryn I. Alpert, Dick J. Veltman, Andrew J. Saykin, Genevieve McPhilemy, Perminder S. Sachdev, Vincent P. Clark, Ian H. Gotlib, Susanne Erk, Henrik Walter, Dennis van den Meer, Simon Cervenka, Oliver Grimm, Andrew M. McIntosh, Alexander Tomyshev, Francisco X. Castellanos, Bernd Kramer, Klaus-Peter Lesch, Odile A. van den Heuvel, Sophia I. Thomopoulos, Diana Tordesillas-Gutiérrez, Terry L. Jernigan, Yulyia Yoncheva, Anouk den Braber, Jim Lagopoulos, Maria J. Portella, Ole A. Andreassen, Gaelle E. Doucet, Avram J. Holmes, Nynke A. Groenewold, Pedro G.P. Rosa, Hilleke E. Hulshoff Pol, Sanne Koops, José M. Menchón, Jan K. Buitelaar, Dan J. Stein, Dorret I. Boomsma, Lei Wang, C.A. Hartman, Pascual Sánchez-Juan, Andreas Heinz

Publikováno v: Karolinska Schizophrenia Project (KaSP) 2022, ' Cortical thickness across the lifespan : Data from 17,075 healthy individuals aged 3–90 years ', Human Brain Mapping, vol. 43, no. 1, pp. 431-451 . https://doi.org/10.1002/hbm.25364
2022, ' Cortical thickness across the lifespan : Data from 17,075 healthy individuals aged 3-90 years ', Human Brain Mapping, vol. 43, no. 1, pp. 431-451 . https://doi.org/10.1002/hbm.25364
Dipòsit Digital de la UB
Universidad de Barcelona
Human Brain Mapping, 43, 431-451
HUMAN BRAIN MAPPING
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Human brain mapping, 43(1), 431-451. Wiley
Human brain mapping 43(1), 431-451 (2022). doi:10.1002/hbm.25364
HUMAN BRAIN MAPPING, 43(1), 431-451. Wiley
Human Brain Mapping
Human Brain Mapping, 43(1):21, 431-451. Wiley-Liss Inc.
Human brain mapping. Wiley-Liss Inc.
Digital.CSIC. Repositorio Institucional del CSIC
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Human Brain Mapping, 43(1), 431-451. WILEY
Human Brain Mapping, 43(1), 431-451. Wiley-Liss Inc.
Frangou, S, Modabbernia, A, Williams, S C R, Papachristou, E, Doucet, G E, Agartz, I, Aghajani, M, Akudjedu, T N, Albajes-eizagirre, A, Alnæs, D, Alpert, K I, Andersson, M, Andreasen, N C, Andreassen, O A, Asherson, P, Banaschewski, T, Bargallo, N, Baumeister, S, Baur-streubel, R, Bertolino, A, Bonvino, A, Boomsma, D I, Borgwardt, S, Bourque, J, Brandeis, D, Breier, A, Brodaty, H, Brouwer, R M, Buitelaar, J K, Busatto, G F, Buckner, R L, Calhoun, V, Canales-rodríguez, E J, Cannon, D M, Caseras, X, Castellanos, F X, Cervenka, S, Chaim-avancini, T M, Ching, C R K, Chubar, V, Clark, V P, Conrod, P, Conzelmann, A, Crespo-facorro, B, Crivello, F, Crone, E A, Dale, A M, Davey, C, Geus, E J C, Haan, L, Zubicaray, G I, Braber, A, Dickie, E W, Di Giorgio, A, Doan, N T, Dørum, E S, Ehrlich, S, Erk, S, Espeseth, T, Fatouros-bergman, H, Fisher, S E, Fouche, J, Franke, B, Frodl, T, Fuentes-claramonte, P, Glahn, D C, Gotlib, I H, Grabe, H, Grimm, O, Groenewold, N A, Grotegerd, D, Gruber, O, Gruner, P, Gur, R E, Gur, R C, Harrison, B J, Hartman, C A, Hatton, S N, Heinz, A, Heslenfeld, D J, Hibar, D P, Hickie, I B, Ho, B, Hoekstra, P J, Hohmann, S, Holmes, A J, Universiteit, R, Hosten, N, Howells, F M, Hulshoff Pol, H E, Huyser, C, Jahanshad, N, James, A, Jernigan, T L, Jiang, J, Jönsson, E G, Joska, J A, Kahn, R, Kalnin, A, Kanai, R, Klein, M, Klyushnik, T P, Koenders, L, Koops, S, Krämer, B, Kuntsi, J, Lagopoulos, J, Lázaro, L, Lebedeva, I, Lee, W H, Lesch, K, Lochner, C, Machielsen, M W J, Maingault, S, Martin, N G, Martínez-zalacaín, I, Mataix-cols, D, Mazoyer, B, Mcdonald, C, Mcdonald, B C, Mcintosh, A M, Mcmahon, K L, Mcphilemy, G, Menchón, J M, Medland, S E, Meyer-lindenberg, A, Naaijen, J, Najt, P, Nakao, T, Nordvik, J E, Nyberg, L, Oosterlaan, J, Foz, V O, Paloyelis, Y, Pauli, P, Pergola, G, Pomarol-clotet, E, Portella, M J, Potkin, S G, Radua, J, Reif, A, Rinker, D A, Roffman, J L, Rosa, P G P, Sacchet, M D, Sachdev, P S, Salvador, R, Sánchez-juan, P, Sarró, S, Satterthwaite, T D, Saykin, A J, Serpa, M H, Schmaal, L, Schnell, K, Schumann, G, Sim, K, Smoller, J W, Sommer, I, Soriano-mas, C, Stein, D J, Strike, L T, Swagerman, S C, Tamnes, C K, Temmingh, H S, Thomopoulos, S I, Tomyshev, A S, Tordesillas-gutiérrez, D, Trollor, J N, Turner, J A, Uhlmann, A, Heuvel, O A, Meer, D, Wee, N J A, Haren, N E M, Ent, D, Erp, T G M, Veer, I M, Veltman, D J, Voineskos, A, Völzke, H, Walter, H, Walton, E, Wang, L, Wang, Y, Wassink, T H, Weber, B, Wen, W, West, J D, Westlye, L T, Whalley, H, Wierenga, L M, Wittfeld, K, Wolf, D H, Worker, A, Wright, M J, Yang, K, Yoncheva, Y, Zanetti, M V, Ziegler, G C, Thompson, P M & Dima, D 2021, ' Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years ', Human Brain Mapping . https://doi.org/10.1002/hbm.25364
Human Brain Mapping, 43(1), 431-451. Wiley
Human Brain Mapping, 43, 1, pp. 431-451
Human brain mapping 43(1), 431-451 (2022). doi:10.1002/hbm.25364 special issue: "Special Issue:The ENIGMA Consortium: the first 10 years / Issue Edited by: P.M. Thompson, N. Jahanshad, L. Schmaal, J.A. Turner, A. Winkler, S.I. Thomopoulos, G.F. Egan, P. Kochunov"
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Frangou, S, Modabbernia, A, Williams, S C R, Papachristou, E, Doucet, G E, Agartz, I, Aghajani, M, Akudjedu, T N, Albajes-eizagirre, A, Alnæs, D, Alpert, K I, Andersson, M, Andreasen, N C, Andreassen, O A, Asherson, P, Banaschewski, T, Bargallo, N, Baumeister, S, Baur-streubel, R, Bertolino, A, Bonvino, A, Boomsma, D I, Borgwardt, S, Bourque, J, Brandeis, D, Breier, A, Brodaty, H, Brouwer, R M, Buitelaar, J K, Busatto, G F, Buckner, R L, Calhoun, V, Canales-rodríguez, E J, Cannon, D M, Caseras, X, Castellanos, F X, Cervenka, S, Chaim-avancini, T M, Ching, C R K, Chubar, V, Clark, V P, Conrod, P, Conzelmann, A, Crespo-facorro, B, Crivello, F, Crone, E A, Dale, A M, Davey, C, de Geus, E J C, Haan, L, Zubicaray, G I, den Braber, A, Dickie, E W, Di Giorgio, A, Doan, N T, Dørum, E S, Ehrlich, S, Erk, S, Espeseth, T, Fatouros-bergman, H, Fisher, S E, Fouche, J, Franke, B, Frodl, T, Fuentes-claramonte, P, Glahn, D C, Gotlib, I H, Grabe, H, Grimm, O, Groenewold, N A, Grotegerd, D, Gruber, O, Gruner, P, Gur, R E, Gur, R C, Harrison, B J, Hartman, C A, Hatton, S N, Heinz, A, Heslenfeld, D J, Hibar, D P, Hickie, I B, Ho, B, Hoekstra, P J, Hohmann, S, Holmes, A J, Hoogman, M, Hosten, N, Howells, F M, Hulshoff Pol, H E, Huyser, C, Jahanshad, N, James, A, Jernigan, T L, Jiang, J, Jönsson, E G, Joska, J A, Kahn, R, Kalnin, A, Kanai, R, Klein, M, Klyushnik, T P, Koenders, L, Koops, S, Krämer, B, Kuntsi, J, Lagopoulos, J, Lázaro, L, Lebedeva, I, Lee, W H, Lesch, K, Lochner, C, Machielsen, M W J, Maingault, S, Martin, N G, Martínez-zalacaín, I, Mataix-cols, D, Mazoyer, B, Mcdonald, C, Mcdonald, B C, Mcintosh, A M, Mcmahon, K L, Mcphilemy, G, Menchón, J M, Medland, S E, Meyer-lindenberg, A, Naaijen, J, Najt, P, Nakao, T, Nordvik, J E, Nyberg, L, Oosterlaan, J, Foz, V O, Paloyelis, Y, Pauli, P, Pergola, G, Pomarol-clotet, E, Portella, M J, Potkin, S G, Radua, J, Reif, A, Rinker, D A, Roffman, J L, Rosa, P G P, Sacchet, M D, Sachdev, P S, Salvador, R, Sánchez-juan, P, Sarró, S, Satterthwaite, T D, Saykin, A J, Serpa, M H, Schmaal, L, Schnell, K, Schumann, G, Sim, K, Smoller, J W, Sommer, I, Soriano-mas, C, Stein, D J, Strike, L T, Swagerman, S C, Tamnes, C K, Temmingh, H S, Thomopoulos, S I, Tomyshev, A S, Tordesillas-gutiérrez, D, Trollor, J N, Turner, J A, Uhlmann, A, Heuvel, O A, Meer, D, Wee, N J A, Haren, N E M, van't Ent, D, Erp, T G M, Veer, I M, Veltman, D J, Voineskos, A, Völzke, H, Walter, H, Walton, E, Wang, L, Wang, Y, Wassink, T H, Weber, B, Wen, W, West, J D, Westlye, L T, Whalley, H, Wierenga, L M, Wittfeld, K, Wolf, D H, Worker, A, Wright, M J, Yang, K, Yoncheva, Y, Zanetti, M V, Ziegler, G C, Thompson, P M & Dima, D 2022, ' Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years ', Human Brain Mapping, vol. 43, no. 1, pp. 431-451 . https://doi.org/10.1002/hbm.25364

Special Issue: The ENIGMA Consortium: the first 10 years.
Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c796c1843983d741f524e3d5040a097c
https://research.rug.nl/en/publications/e5880320-1d45-48cd-a125-ccda26208929

Effects of Mu-Opiate Receptor Gene Polymorphism rs1799971 (A118G) on the Antidepressant and Dissociation Responses in Esketamine Nasal Spray Clinical Trials

Autor: Hartmuth C. Kolb, Wayne C. Drevets, Vanina Popova, Ziad S. Saad, Maggie Fedgchin, Maura L. Furey, Guang Chen, Jaskaran Singh, Derrek P. Hibar

Publikováno v: International Journal of Neuropsychopharmacology

BackgroundAt ketamine and esketamine doses at which antidepressant doses are achieved, these agents are relatively selective, noncompetitive, N-methyl-D-aspartate receptor antagonists. However, at substantially higher doses, ketamine has shown mu-opi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360407ff3972b5cd095a0564442547af
http://europepmc.org/articles/PMC7710914