Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Dermot Cox"'
Publikováno v:
HemaSphere, Vol 7, p e9020579 (2023)
Externí odkaz:
https://doaj.org/article/d54a853b8502471bb92694f2d67cb5f4
Autor:
Dermot Cox
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is associated with mortality. This thrombocytopenia is characteristic of disseminated intravascular coagulation (DIC), the sepsis-associated coagulopathy. Many of the
Externí odkaz:
https://doaj.org/article/34406ef52b8f432990af713c43daf040
Publikováno v:
Platelets, Vol 31, Iss 4, Pp 530-535 (2020)
Aspirin non-response is associated with poor outcome but there is no agreement between the different methods to asses it. Weight has been shown to be a predictor of poor response but only using one method. In this study, we determine the effects of w
Externí odkaz:
https://doaj.org/article/e13ac5a112ac4412a328a00c814e5a63
Autor:
Dermot Cox
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
It is clear that COVID-19 is more than a pneumonia and is associated with a coagulopathy and multi-organ failure. While the use of anti-coagulants does reduce the incidence of pulmonary emboli, it does not help with survival. This suggests that the c
Externí odkaz:
https://doaj.org/article/d48338f0c65e4e59a96a0124cb9c2e5d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. While many individual cells and systems in the body are involved in driving the excessive and sometimes sustained host response, pathogen eng
Externí odkaz:
https://doaj.org/article/eb300a5e8ac64273847a2ab426fcf83f
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 6, p e2858 (2014)
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors t
Externí odkaz:
https://doaj.org/article/5492912855814f3eb084b29a7b267cfa
Autor:
Dermot Cox
Publikováno v:
ISBT Science Series. 15:131-141
Autor:
Ireland Amnch, Ryan Dj, Offiah C, McCabe Djh, Murphy Sjx, Collins Dr, Dermot Cox, Egan B, Dominique R. Smith, Delaney S, McCarthy Aj, Amnch, Dublin, Ireland
Publikováno v:
Thrombosis & Haemostasis: Research. 5
Introduction: The optimal time interval after venepuncture to perform platelet function/reactivity testing at low shear stress on the novel AGGRESTAR PL-12® platelet function analyser in non-Chinese Cerebrovascular Disease (CVD) patients is unknown.
Publikováno v:
Platelets. 31:530-535
Aspirin non-response is associated with poor outcome but there is no agreement between the different methods to asses it. Weight has been shown to be a predictor of poor response but only using one method. In this study, we determine the effects of w
Autor:
Bridget Egan, Justin A. Kinsella, Joseph Harbison, Dermot Cox, George Hamilton, Dominick J. H. McCabe, Prakash Madhavan, Sinéad M. Murphy, T. Coughlan, Stephen J.X. Murphy, Sean O’Neill, Niamh Moran, Mary Paula Colgan, Sean Tierney, Soon Tjin Lim, Desmond O'Neill, Richard A. Walsh, D. R. Collins, T. M. Feeley
Publikováno v:
Thrombosis and Haemostasis. 119:821-833
Introduction Cerebral micro-embolic signals (MES) predict risk of stroke in carotid stenosis patients. However, MES-negative ‘recently symptomatic patients’ also have a higher stroke risk than ‘asymptomatic patients’. Differences in platelet