Výsledky vyhledávání - "Dermatology/Atopic Dermatitis and Other Forms of Eczema"

A randomised controlled trial of ion-exchange water softeners for the treatment of eczema in children

Autor: Kim S, Thomas, Tara, Dean, Caroline, O'Leary, Tracey H, Sach, Karin, Koller, Anthony, Frost, Hywel C, Williams, Amanda, Roper

Publikováno v: PLoS Medicine
PLoS Medicine, Vol 8, Iss 2, p e1000395 (2011)

In a randomized trial evaluating the effect of installation of ion-exchange water softeners in the households of children with eczema, the researchers found no evidence of improvement in eczema severity as compared to usual care in the study populati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee20061c781e4ff500b8688267dcb0a
https://pubmed.ncbi.nlm.nih.gov/22006138

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Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy

Autor: Thomas A. Luger, Cord Sunderkötter, I. Herrgott, Dorothee Siepmann, Sonja Ständer

Publikováno v: PLoS ONE, Vol 5, Iss 6, p e10968 (2010)
PLoS ONE

BackgroundChronic pruritus is a global clinical problem with a high impact on the quality of life and lack of specific therapies. It is an excruciating and frequent symptom of e.g. uncurable renal, liver and skin diseases which often does not respond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2465050e75e41ab47511b35049c67dfd
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20532044/?tool=EBI

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Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis

Autor: Kaare Engkilde, Karsten Buschard, Torkil Menné, Axel Kornerup Hansen, Jeanne D. Johansen

Publikováno v: PLoS ONE, Vol 5, Iss 5, p e10591 (2010)
Engkilde, K, Buschard, K, Hansen, A J K, Menné, T & Johansen, J D 2010, ' Prevention of diabetes in NOD mice by repeated exposures to a contact allergen inducing a sub-clinical dermatitis ', PLoS ONE, vol. 5, no. 5, pp. e10591 . https://doi.org/10.1371/journal.pone.0010591
PLoS ONE

BACKGROUND: Type 1 diabetes is an autoimmune disease, while allergic contact dermatitis although immune mediated, is considered an exposure driven disease that develops due to epicutaneous contact with reactive low-molecular chemicals. The objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8ea5e9f43acd8cb4fa365fe5beafbc
http://europepmc.org/articles/PMC2868032?pdf=render

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Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults

Autor: Johan Holmkvist, Camilla Noelle Rathcke, Torben Hansen, Lise Lotte N. Husmoen, Henrik Vestergaard, Oluf Pedersen, Allan Linneberg

Publikováno v: PLoS ONE, Vol 4, Iss 7, p e6106 (2009)
Rathcke, C N, Holmkvist, J, Husmoen, L L N, Hansen, T, Pedersen, O, Vestergaard, H & Linneberg, A 2009, ' Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults ', PLoS ONE, vol. 4, no. 7, pp. e6106 . https://doi.org/10.1371/journal.pone.0006106
PLoS ONE

Udgivelsesdato: 2009-null BACKGROUND: YKL-40 is a chitinase-like glycoprotein encoded by the chitinase 3-like 1 gene, CHI3L1, localized at chromosome 1q32.1. Increased levels of serum YKL-40 have been reported to be a biomarker for asthma and a reduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38fcf1b1dcb5183e02840edddc4d6ad
http://europepmc.org/articles/PMC2699472?pdf=render

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

Autor: Mitsuru Morimoto, Michael J. Holtzman, Shadmehr Demehri, Raphael Kopan

Publikováno v: PLoS Biology, Vol 7, Iss 5, p e1000067 (2009)
PLoS Biology

A skin-derived cytokine with high systemic availability provides a mechanistic explanation for atopic march and highlights a potential therapeutic target for preventing the development of asthma among people with atopic dermatitis.
Asthma is a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7a5802f029ef43fa865b89f25b24e1
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19557146/?tool=EBI

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Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes

Autor: Jennifer M. Taylor, Martin S. Taylor, Gina Stolper, Richard R. Copley, Teresa L Street, William O.C.M. Cookson, Miriam F. Moffatt, Lizhong Hao, Jotun Hein, Richard Mott, Patrick Hayden

Publikováno v: Taylor, J M, Street, T L, Hao, L, Copley, R, Taylor, M S, Hayden, P J, Stolper, G, Mott, R, Hein, J, Moffatt, M F & Cookson, W O C M 2009, ' Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes ', PLoS ONE, vol. 4, no. 10, pp. e7651 . https://doi.org/10.1371/journal.pone.0007651
PLoS ONE, Vol 4, Iss 10, p e7651 (2009)
PLoS ONE
e7651

The mammalian epidermis is a continually renewing structure that provides the interface between the organism and an innately hostile environment. The keratinocyte is its principal cell. Keratinocyte proteins form a physical epithelial barrier, protec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549ddf4b4bd13c4dc639c78f93b34976
https://www.pure.ed.ac.uk/ws/files/7765452/Dynamic_and_physical_clustering_of_gene_expression_during_epidermal_barrier_formation_in_differentiating_keratinocytes.pdf

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Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin

Autor: Patrick A. M. Jansen, Patrick L.J.M. Zeeuwen, Elke M. G. J. de Jong, Judith G.M. Bergboer, Michelle M. van Rossum, Andrea W M Evers, Mieke Bergers, Gys J. de Jongh, Geuranne S. Tjabringa, Diana Rodijk-Olthuis, Edward J. Hollox, Marijke Kamsteeg, Ivonne M.J.J. van Vlijmen-Willems, John A.L. Armour, Joost Schalkwijk, Martin den Heijer

Publikováno v: PLoS ONE
PLoS One, 4, 3
PLoS ONE 4 (2009) 3
PLoS ONE, Vol 4, Iss 3, p e4725 (2009)
PLoS One, 4
PLoS ONE, 4(3)

Contains fulltext : 80466.pdf (Publisher’s version ) (Open Access) BACKGROUND: Previous studies have extensively documented antimicrobial and chemotactic activities of beta-defensins. Human beta-defensin-2 (hBD-2) is strongly expressed in lesional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8abfd8f28cb866e51f3748cdf47b94b
https://pubmed.ncbi.nlm.nih.gov/19266104

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The Incidence of Molluscum contagiosum among American Indians and Alaska Natives

Autor: Krista Y. Christensen, Robert C. Holman, Inger K. Damon, James E. Cheek, Mary G. Reynolds

Publikováno v: PLoS ONE
PLoS ONE, Vol 4, Iss 4, p e5255 (2009)

BackgroundThe epidemiology of Molluscum contagiosum (MC) in the United States is largely unknown, despite the fact that the virus is directly communicable and large outbreaks occur. This study provides population-based estimates to describe the epide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c31372a0ed50353dac17f0f724ed335
https://pubmed.ncbi.nlm.nih.gov/19381289

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