Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Derler, P"'
Autor:
Valentina Hopl, Adéla Tiffner, Armin Wutscher, Matthias Sallinger, Herwig Grabmayr, Magdalena Prantl, Maximilian Fröhlich, Julia Söllner, Sarah Weiß, Hadil Najjar, Yuliia Nazarenko, Selina Harant, Natalia Kriško, Marc Fahrner, Christina Humer, Carmen Höglinger, Heinrich Krobath, Daniel Bonhenry, Isabella Derler
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The activation of the Ca2+-channel Orai1 via the physiological activator stromal interaction molecule 1 (STIM1) requires structural rearrangements within the entire channel complex involving a series of gating checkpoints. Focusing on the ga
Externí odkaz:
https://doaj.org/article/8dd11424e2484702a86a69fef72125d9
Autor:
Sophia E. Chrysostomou, Sandra Eder, Isabella Pototschnig, Anna‐Lena Mayer, Martina Derler, Marion Mussbacher, Silvia Schauer, Dongxu Zhang, Dongmei Yan, Gennie Liu, Gerald Hoefler, Thomas Weichhart, Paul W. Vesely, Lingbing Zhang, Martina Schweiger
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 562-574 (2024)
Abstract Background Cancer‐associated cachexia (CAC) is a debilitating syndrome associated with poor quality of life and reduced life expectancy of cancer patients. CAC is characterized by unintended body weight reduction due to muscle and adipose
Externí odkaz:
https://doaj.org/article/900272734f5246308cda047cdd899863
Publikováno v:
Verfassungsblog, Iss 2366-7044 (2024)
In June 2024, delegates undertook two-week-long negotiations at the UNFCCC Bonn Climate Change Conference. These meetings concerned the modalities of the newly instituted Loss and Damage (L&D) Fund and the provision of financial assistance to develop
Externí odkaz:
https://doaj.org/article/1695154f48f44522a4a63199792a3ae2
Akademický článek
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Autor:
Lena Maltan, Sarah Weiß, Hadil Najjar, Melanie Leopold, Sonja Lindinger, Carmen Höglinger, Lorenz Höbarth, Matthias Sallinger, Herwig Grabmayr, Sascha Berlansky, Denis Krivic, Valentina Hopl, Anna Blaimschein, Marc Fahrner, Irene Frischauf, Adéla Tiffner, Isabella Derler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The Ca2+ ion channel Orai1 is crucial in immune cells. Here, the authors applied genetic code expansion to transfer light-sensitivity to the Orai1 channel and achieved precise control over its function.
Externí odkaz:
https://doaj.org/article/bee2dd102ac04d1e8838711cbc3c5162
Akademický článek
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Publikováno v:
Cells, Vol 13, Iss 6, p 468 (2024)
Many essential biological processes are triggered by the proximity of molecules. Meanwhile, diverse approaches in synthetic biology, such as new biological parts or engineered cells, have opened up avenues to precisely control the proximity of molecu
Externí odkaz:
https://doaj.org/article/99e58ca849664aac99ea02977f43efcf
Publikováno v:
Humanities & Social Sciences Communications, Vol 9, Iss 1, Pp 1-13 (2022)
Abstract Autonomous vehicles (AVs) are being developed, tested, and commercialized around the world. While skilled human drivers can rely on their experience and common sense to navigate complex driving situations that involve trade-offs between comp
Externí odkaz:
https://doaj.org/article/05a794ce6a1946a997f8804f62c5f170
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein family members. It plays an essential role in inflammation and immunity by regulating the expression of numerous chemokines, cytokines, transcription fac
Externí odkaz:
https://doaj.org/article/d7254689363542d782c52b4ef6a73792
Akademický článek
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