Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Derk Hogenkamp"'
Autor:
Rían W. Manville, Ryan F. Yoshimura, Andriy V. Yeromin, Derk Hogenkamp, Jennifer van der Horst, Angel Zavala, Sonia Chinedu, Grey Arena, Emma Lasky, Mark Fisher, Christopher R. Tracy, Shivashankar Othy, Thomas A. Jepps, Michael D. Cahalan, Geoffrey W. Abbott
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Pain and inflammation contribute immeasurably to reduced quality of life, yet modern analgesic and anti-inflammatory therapeutics can cause dependence and side effects. Here, we screened 1444 plant extracts, prepared primarily from native sp
Externí odkaz:
https://doaj.org/article/5bae3235538b444ea2fc2392f2ec6cbc
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Voltage-gated potassium (Kv) channels in the KCNQ subfamily serve essential roles in the nervous system, heart, muscle and epithelia. Different heteromeric KCNQ complexes likely serve distinct functions in the brain but heteromer subtype-spe
Externí odkaz:
https://doaj.org/article/df90b352ce0044b6b23fe2eb931818f1
Publikováno v:
Neurobiology of Stress, Vol 12, Iss , Pp - (2020)
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR). These reports were followed by the discovery that
Externí odkaz:
https://doaj.org/article/8b28a0f5a73447948d30996d5d43b0e6
Autor:
Timothy B. C. Johnstone, Hilary S. McCarren, Jay Spampanato, F. Edward Dudek, John H. McDonough, Derk Hogenkamp, Kelvin W. Gee
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABAARs) that rapidly internalize during status epilepticus (SE). Extr
Externí odkaz:
https://doaj.org/article/25d1ae99c446488ba9de5d89a56a1187
Autor:
David J Titus, Timothy Johnstone, Nathan H Johnson, Sidney H London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkins
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223180 (2019)
Cognitive impairments are a common consequence of traumatic brain injury (TBI). The hippocampus is a subcortical structure that plays a key role in the formation of declarative memories and is highly vulnerable to TBI. The α7 nicotinic acetylcholine
Externí odkaz:
https://doaj.org/article/3f694b47493b4a208cd553c02152427b
Publikováno v:
Neurobiology of Stress
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR). These reports were followed by the discovery that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edea4e6cd234a698752ad2b82527aa62
https://pubmed.ncbi.nlm.nih.gov/32435660
https://pubmed.ncbi.nlm.nih.gov/32435660