Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Derk D, Purcell"'
Autor:
Joanna L. Shuping, Dawn C. Matthews, Katarzyna Adamczuk, David Scott, Christopher C. Rowe, William C. Kreisl, Sterling C. Johnson, Ana S. Lukic, Keith A. Johnson, Pedro Rosa‐Neto, Randolph D. Andrews, Koen Van Laere, Lindsay Cordes, Larry Ward, Claire L. Wilde, Jerome Barakos, Derk D. Purcell, Davangere P. Devanand, Yaakov Stern, Jose A. Luchsinger, Cyrille Sur, Julie C. Price, Adam M. Brickman, William E. Klunk, Adam L. Boxer, Sulantha S. Mathotaarachchi, Patrick J. Lao, Jeffrey L. Evelhoch
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 1, Pp n/a-n/a (2023)
Abstract Background The positron emission tomography (PET) radiotracer [18F]MK‐6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, a
Externí odkaz:
https://doaj.org/article/d292970eb93a4e9c97bfc3b0e3aca902
Autor:
Guanfang Wang, Samantha Budd Haeberlein, Spyros Chalkias, Kimberly Umans, Karen Smirnakis, Frederik Barkhof, Derk D. Purcell, Patrick Burkett, Joyce Suhy, Jerome Barakos, Stephen Salloway, Priya Singhal, Fiona Forrestal, Ying Tian
Publikováno v:
JAMA Neurology, 79(1), 13-21. American Medical Association
Salloway, S, Chalkias, S, Barkhof, F, Burkett, P, Barakos, J, Purcell, D, Suhy, J, Forrestal, F, Tian, Y, Umans, K, Wang, G, Singhal, P, Budd Haeberlein, S & Smirnakis, K 2022, ' Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients with Early Alzheimer Disease ', JAMA Neurology, vol. 79, no. 1, pp. 13-21 . https://doi.org/10.1001/jamaneurol.2021.4161
JAMA Neurology
Salloway, S, Chalkias, S, Barkhof, F, Burkett, P, Barakos, J, Purcell, D, Suhy, J, Forrestal, F, Tian, Y, Umans, K, Wang, G, Singhal, P, Budd Haeberlein, S & Smirnakis, K 2022, ' Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients with Early Alzheimer Disease ', JAMA Neurology, vol. 79, no. 1, pp. 13-21 . https://doi.org/10.1001/jamaneurol.2021.4161
JAMA Neurology
Key Points Question What are the characteristics of amyloid-related imaging abnormalities (ARIA) during aducanumab treatment in individuals with early Alzheimer disease? Findings In an integrated safety data set of 2 phase 3 clinical trials (EMERGE a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e6460af171fc31f9c91d3f80934ed4
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119965458&origin=inward
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119965458&origin=inward
Autor:
Patrick Burkett, Spyros Chalkias, Kimberly Umans, Carmen Castrillo‐Viguera, Derk D Purcell, Jerome Barakos, Sami Fam, Karen Smirnakis, Samantha Budd Haeberlein
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e194b209777c57c144bb495983f47f2
https://doi.org/10.1002/alz.057498
https://doi.org/10.1002/alz.057498
Autor:
Derk D. Purcell, Paulo Fontoura, Rachelle Doody, Paul Delmar, Geoffrey A. Kerchner, Gregory Klein, Monika Baudler, Luc Bracoud, Szofia S. Bullain, Danielle Abi-Saab, Jerome Barakos
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a4f44cbce6823e1bde7195548561a4
https://doi.org/10.1002/alz.041110
https://doi.org/10.1002/alz.041110
Autor:
Derk D. Purcell, H. Michael Arrighi, Esther Sanchez Aliaga, Marita Daams, H. Robert Brashear, Frederik Barkhof, Mike P. Wattjes, Arianne Bechten
Publikováno v:
Journal of Neuroimaging. 27:318-325
INTRODUCTION Immunotherapeutic agents against amyloid beta (Aβ) are associated with adverse events, including amyloid-related imaging abnormalities with edema and effusion (ARIA-E). Recently, a magnetic resonance imaging (MRI) rating scale was devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04082e77dc22fd964643d67e9a49375
https://doi.org/10.1111/jon.12422
https://doi.org/10.1111/jon.12422
Autor:
Derk D. Purcell, Tianle Chen, Joonmi Oh, Ping Chiao, Joyce Suhy, Jerome Barakos, Ajay Verma, Jeff Sevigny, Gregory Klein, Mehul Sampat
Publikováno v:
Alzheimer Disease & Associated Disorders. 30:1-7
Amyloid positron emission tomography (PET) imaging is being investigated as a screening tool to identify amyloid-positive patients as an enrichment strategy for Alzheimer disease (AD) clinical trial enrollment. In a multicenter, phase 1b trial, patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5aff59ee0c4dac73740f756c1ce1ff
https://doi.org/10.1097/wad.0000000000000144
https://doi.org/10.1097/wad.0000000000000144
Autor:
Derk D. Purcell, Frederik Barkhof, Roland M. Martens, Silvia Ingala, Arianne Bechten, Robert H. Brashear, Esther Sanchez, Mike P. Wattjes, Michael Arrighi, Ronald A. van Schijndel, Vania B. Machado, Marcus C. de Jong
Publikováno v:
Martens, R M, Bechten, A, Ingala, S, van Schijndel, R A, Machado, V B, de Jong, M C, Sanchez, E, Purcell, D, Arrighi, M H, Brashear, R H, Wattjes, M P & Barkhof, F 2018, ' The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer’s patients : An interobserver study ', European Radiology, vol. 28, no. 3, pp. 1-12 . https://doi.org/10.1007/s00330-017-5022-6
European Radiology, 28(3), 1-12. Springer Verlag
European Radiology
European Radiology, 28(3), 1-12. Springer Verlag
European Radiology
Background: Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer’s disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80077929c94d709fd5edd41c9d3c148c
https://research.vumc.nl/en/publications/568ea189-d6ae-418e-b523-12e950f28da9
https://research.vumc.nl/en/publications/568ea189-d6ae-418e-b523-12e950f28da9
Autor:
Achim Gass, Camilla Lindan, Joyce Suhy, Jerome Barakos, Derk D. Purcell, Jochen B. Fiebach, Luc Bracoud, Erik Gaensler
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9133b26d4c264203e15c3169f11dde
https://doi.org/10.1016/j.jalz.2017.06.114
https://doi.org/10.1016/j.jalz.2017.06.114
Autor:
Derk D. Purcell, Roland M. Martens, Frederik Barkhof, Mike P. Wattjes, Arianne Bechten, Robert H. Brashear, Esther Sanchez, Ronald A. van Schijndel, Silvia Ingala, Marcus C. de Jong, Vania B. Machado, Michael Arrighi
Publikováno v:
Alzheimer's & Dementia. 13
Background: Amyloid-s plaques are considered the hallmark of Alzheimer's disease (AD). Immunotherapeutic strategies targeting Abeta have shown promising results, although they are associated with adverse events, including amyloid-related imaging abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39bb2e0f06887c4543e62c748315b731
https://doi.org/10.1016/j.jalz.2017.06.416
https://doi.org/10.1016/j.jalz.2017.06.416
Autor:
Joyce Suhy, Luc Bracoud, Erik Gaensler, Achim Gass, Jerome Barakos, Jochen B. Fiebach, Derk D. Purcell, Camilla Lindan
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b58ee0b3b73724d40d3c0b64bab1de2
https://doi.org/10.1016/j.jalz.2017.06.2311
https://doi.org/10.1016/j.jalz.2017.06.2311