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pro vyhledávání: '"Derick H. Lindquist"'
Autor:
Derick H. Lindquist
Publikováno v:
Neuroscience and biobehavioral reviews. 115
An organism's ability to adapt to environmental challenges is aided by disparate neural systems, acting independently and interactively to influence behavioral responding. With respect to associative learning, emotional, contextual, and sensorimotor
Autor:
David Phenis, John P. Bruno, Robert Schwarcz, Derick H. Lindquist, Valentina Valentini, Michelle L. Pershing, Ana Pocivavsek
Publikováno v:
Psychopharmacology. 233:3725-3735
Levels of kynurenic acid (KYNA), an endogenous negative modulator of alpha 7 nicotinic acetylcholine receptors (α7nAChRs) and antagonist at glutamatergic N-methyl-D-aspartate receptors (NMDARs), are elevated in the brain of patients with schizophren
Publikováno v:
Behavioural brain research. 338
Impairments in behavior and cognition are common in individuals diagnosed with fetal alcohol spectrum disorders (FASD). In this study, FASD model rats were intragastrically intubated with ethanol (5 g/kg/day; 5E), sham-intubated (SI), or maintained a
Autor:
Derick H. Lindquist
Publikováno v:
Behavioural Brain Research. 242:191-199
Binge-like postnatal ethanol exposure produces significant damage throughout the brain in rats, including the cerebellum and hippocampus. In the current study, cue- and context-mediated Pavlovian conditioning were assessed in adult rats exposed to mo
Publikováno v:
Neurobiology of Learning and Memory. 94:167-175
Early in eyeblink classical conditioning, amygdala-dependent fear responding is reported to facilitate acquisition of the cerebellar-dependent eyeblink conditioned response (CR), in accord with the two-process model of conditioning (Konorski, 1967).
Publikováno v:
Physiology & Behavior. 96:399-411
Over the last several years, a growing number of investigators have begun using the rat in classical eyeblink conditioning experiments, yet relatively few parametric studies have been done to examine the nature of conditioning in this species. We rep
Publikováno v:
Behavioral Neuroscience. 123:62-74
The role of the cerebellar cortex in eyeblink classical conditioning remains unclear. Experimental manipulations that disrupt the normal function of this region impair learning to various degrees and task parameters may be important factors in determ
Autor:
Derick H. Lindquist, Joseph M. Pochiro
Publikováno v:
Learningbehavior. 44(2)
In delay eyeblink conditioning (EBC) a neutral conditioned stimulus (CS; tone) is repeatedly paired with a mildly aversive unconditioned stimulus (US; periorbital electrical shock). Over training, subjects learn to produce an anticipatory eyeblink co
Publikováno v:
Alcoholism, clinical and experimental research. 40(2)
Background Ethanol (EtOH) exposure in neonate rats during a period comparable to the human third trimester, postnatal days (PD) 4 to 9, leads to persistent deficits in forebrain-dependent cognitive function—modeling the dysfunction seen in individu
Publikováno v:
Behavioral neuroscience. 128(2)
Utilizing a rat model of fetal alcohol spectrum disorder (FASD), ethanol was administered over postnatal days (PD) 4 to 9. As adults, control and ethanol rats underwent trace fear conditioning (TFC), in which a tone conditioned stimulus (CS) and foot