Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Deric M Park"'
Autor:
Dae-Hee Lee, Ying Zhang, Amin B Kassam, Myung-Jin Park, Paul Gardner, Daniel Prevedello, Stephanie Henry, Craig Horbinski, Jan H Beumer, Hussein Tawbi, Brian J Williams, Mark E Shaffrey, Merrill J Egorin, Roger Abounader, Deric M Park
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134426 (2015)
The majority of chordomas show activation of the platelet-derived growth factor receptor (PDGFR). Based on in vitro intertumoral variation in response to recombinant PDGF protein and PDGFR inhibition, and variable tumor response to imatinib, we hypot
Externí odkaz:
https://doaj.org/article/b9e40afa3cfc436788788ef2f5fd5a4d
Autor:
Simone Pacioni, Maria Adele Rueger, Giuseppe Nisticò, Stefan R Bornstein, Deric M Park, Ron D McKay, Andreas Androutsellis-Theotokis
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51630 (2012)
The adult hippocampus is involved in learning and memory. As a consequence, it is a brain region of remarkable plasticity. This plasticity exhibits itself both as cellular changes and neurogenesis. For neurogenesis to occur, a population of local ste
Externí odkaz:
https://doaj.org/article/28ff784178b0438ca55825887688d18c
Autor:
Andreas Androutsellis-Theotokis, Stuart Walbridge, Deric M Park, Russell R Lonser, Ronald D G McKay
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10841 (2010)
New mechanisms that regulate neural stem cell (NSC) expansion will contribute to improved assay systems and the emerging regenerative approach that targets endogenous stem cells. Expanding knowledge on the control of stem cell self renewal will also
Externí odkaz:
https://doaj.org/article/3e347f6deaa748b0b3e46f8b6ba727a0
Autor:
Andreas Androutsellis-Theotokis, Maria A Rueger, Deric M Park, Justin D Boyd, Raji Padmanabhan, Loraine Campanati, Craig V Stewart, Yann LeFranc, Dietmar Plenz, Stuart Walbridge, Russell R Lonser, Ronald D G McKay
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9414 (2010)
The ability to grow a uniform cell type from the adult central nervous system (CNS) is valuable for developing cell therapies and new strategies for drug discovery. The adult mammalian brain is a source of neural stem cells (NSC) found in both neurog
Externí odkaz:
https://doaj.org/article/0d236fde47db43fc807832f757dcfba8
Autor:
Deric M Park, Zhengping Zhuang, Ling Chen, Nicholas Szerlip, Irina Maric, Jie Li, Taesung Sohn, Stephanie H Kim, Irina A Lubensky, Alexander O Vortmeyer, Griffin P Rodgers, Edward H Oldfield, Russell R Lonser
Publikováno v:
PLoS Medicine, Vol 4, Iss 2, p e60 (2007)
BACKGROUND: To determine the origin of the neoplastic cell in central nervous system (CNS) hemangioblastomas in von Hippel-Lindau disease (VHL) and its role in tumor formation and distribution, we characterized and differentiated neoplastic cells fro
Externí odkaz:
https://doaj.org/article/e930360105c74d679d4f7e92f0642a91
Autor:
Herui Wang, Rogelio Medina, Juan Ye, Yaping Zhang, Samik Chakraborty, Alex Valenzuela, Ondrej Uher, Katerina Hadrava Vanova, Mitchell Sun, Xueyu Sang, Deric M. Park, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting “cold” GBMs to “hot” is crucial for immune activation and impro
Externí odkaz:
https://doaj.org/article/402be77c1897447c8a899980d3ead908
Autor:
Joshua E. Allen, Wolfgang Oster, Patrick Y. Wen, Tracy T. Batchelor, Isabel Arrillaga-Romany, Robert Wechsler-Reya, Jessica Rusert, Mark R. Gilbert, Deric M. Park, Jinkyu Jung, Neil Charter, Sean Deacon, Rohinton S. Tarapore, Jessica Durrant, Alexander VanEngelenburg, Faye Doherty, Olivier Elemento, Wafik S. El-Deiry, Sophie Oster, C. Leah B. Kline, Coryandar Gilvary, Neel S. Madhukar, Varun V. Prabhu
Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e308d507bf1d92c73420b66051a502d5
https://doi.org/10.1158/1078-0432.22472331
https://doi.org/10.1158/1078-0432.22472331
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
NIX-mediated mitophagy is related with hypoxia-induced macroautophagy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee1e4c934bb44394f81b1e419b7cc3c
https://doi.org/10.1158/0008-5472.22422116.v1
https://doi.org/10.1158/0008-5472.22422116.v1
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
Cancer cells rely on mitochondrial functions to regulate key survival and death signals. How cancer cells regulate mitochondrial autophagy (mitophagy) in the tumor microenvironment as well as utilize mitophagy as a survival signal is still not well u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56def3906463b5bad43267795893345
https://doi.org/10.1158/0008-5472.c.6511130.v1
https://doi.org/10.1158/0008-5472.c.6511130.v1
Autor:
Joshua E. Allen, Wolfgang Oster, Patrick Y. Wen, Tracy T. Batchelor, Isabel Arrillaga-Romany, Robert Wechsler-Reya, Jessica Rusert, Mark R. Gilbert, Deric M. Park, Jinkyu Jung, Neil Charter, Sean Deacon, Rohinton S. Tarapore, Jessica Durrant, Alexander VanEngelenburg, Faye Doherty, Olivier Elemento, Wafik S. El-Deiry, Sophie Oster, C. Leah B. Kline, Coryandar Gilvary, Neel S. Madhukar, Varun V. Prabhu
Purpose:Dopamine receptor D2 (DRD2) is a G protein–coupled receptor antagonized by ONC201, an anticancer small molecule in clinical trials for high-grade gliomas and other malignancies. DRD5 is a dopamine receptor family member that opposes DRD2 si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5247f7654a50fe6322025926a51c4f46
https://doi.org/10.1158/1078-0432.c.6528195
https://doi.org/10.1158/1078-0432.c.6528195