Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Deric M Park"'
Autor:
Herui Wang, Rogelio Medina, Juan Ye, Yaping Zhang, Samik Chakraborty, Alex Valenzuela, Ondrej Uher, Katerina Hadrava Vanova, Mitchell Sun, Xueyu Sang, Deric M. Park, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting “cold” GBMs to “hot” is crucial for immune activation and impro
Externí odkaz:
https://doaj.org/article/402be77c1897447c8a899980d3ead908
Autor:
Amber J. Giles, Marsha-Kay N. D. Hutchinson, Heather M. Sonnemann, Jinkyu Jung, Peter E. Fecci, Nivedita M. Ratnam, Wei Zhang, Hua Song, Rolanda Bailey, Dionne Davis, Caitlin M. Reid, Deric M. Park, Mark R. Gilbert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Background Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. Howeve
Externí odkaz:
https://doaj.org/article/dbbd8ceab8b343afa6a998b078f2f24a
Autor:
Surabhi Ranjan, Martha Quezado, Nancy Garren, Lisa Boris, Christine Siegel, Osorio Lopes Abath Neto, Brett J. Theeler, Deric M. Park, Edjah Nduom, Kareem A. Zaghloul, Mark R. Gilbert, Jing Wu
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Immune checkpoint inhibitors (ICPIs) are being investigated in clinical trials for patients with glioblastoma. While these therapies hold great promise, management of the patients receiving such treatment can be complicated due to
Externí odkaz:
https://doaj.org/article/6469175576734a80abd564c4cc0fe604
Autor:
Joshua E. Allen, Wolfgang Oster, Patrick Y. Wen, Tracy T. Batchelor, Isabel Arrillaga-Romany, Robert Wechsler-Reya, Jessica Rusert, Mark R. Gilbert, Deric M. Park, Jinkyu Jung, Neil Charter, Sean Deacon, Rohinton S. Tarapore, Jessica Durrant, Alexander VanEngelenburg, Faye Doherty, Olivier Elemento, Wafik S. El-Deiry, Sophie Oster, C. Leah B. Kline, Coryandar Gilvary, Neel S. Madhukar, Varun V. Prabhu
Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e308d507bf1d92c73420b66051a502d5
https://doi.org/10.1158/1078-0432.22472331
https://doi.org/10.1158/1078-0432.22472331
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
NIX-mediated mitophagy is related with hypoxia-induced macroautophagy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee1e4c934bb44394f81b1e419b7cc3c
https://doi.org/10.1158/0008-5472.22422116.v1
https://doi.org/10.1158/0008-5472.22422116.v1
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
Cancer cells rely on mitochondrial functions to regulate key survival and death signals. How cancer cells regulate mitochondrial autophagy (mitophagy) in the tumor microenvironment as well as utilize mitophagy as a survival signal is still not well u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56def3906463b5bad43267795893345
https://doi.org/10.1158/0008-5472.c.6511130.v1
https://doi.org/10.1158/0008-5472.c.6511130.v1
Autor:
Joshua E. Allen, Wolfgang Oster, Patrick Y. Wen, Tracy T. Batchelor, Isabel Arrillaga-Romany, Robert Wechsler-Reya, Jessica Rusert, Mark R. Gilbert, Deric M. Park, Jinkyu Jung, Neil Charter, Sean Deacon, Rohinton S. Tarapore, Jessica Durrant, Alexander VanEngelenburg, Faye Doherty, Olivier Elemento, Wafik S. El-Deiry, Sophie Oster, C. Leah B. Kline, Coryandar Gilvary, Neel S. Madhukar, Varun V. Prabhu
Purpose:Dopamine receptor D2 (DRD2) is a G protein–coupled receptor antagonized by ONC201, an anticancer small molecule in clinical trials for high-grade gliomas and other malignancies. DRD5 is a dopamine receptor family member that opposes DRD2 si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5247f7654a50fe6322025926a51c4f46
https://doi.org/10.1158/1078-0432.c.6528195
https://doi.org/10.1158/1078-0432.c.6528195
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
NIX is functional for responding oxidative stress signal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb7b26043757bd31c8f43a161bd2a8e
https://doi.org/10.1158/0008-5472.22422110
https://doi.org/10.1158/0008-5472.22422110
Autor:
Joshua E. Allen, Wolfgang Oster, Patrick Y. Wen, Tracy T. Batchelor, Isabel Arrillaga-Romany, Robert Wechsler-Reya, Jessica Rusert, Mark R. Gilbert, Deric M. Park, Jinkyu Jung, Neil Charter, Sean Deacon, Rohinton S. Tarapore, Jessica Durrant, Alexander VanEngelenburg, Faye Doherty, Olivier Elemento, Wafik S. El-Deiry, Sophie Oster, C. Leah B. Kline, Coryandar Gilvary, Neel S. Madhukar, Varun V. Prabhu
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86181d49990cf8948bf53f9c5827dffc
https://doi.org/10.1158/1078-0432.22472319
https://doi.org/10.1158/1078-0432.22472319
Autor:
Deric M. Park, Mark R. Gilbert, Roger Abounader, Jeremy N. Rich, Amber J. Giles, Brian J. Williams, Hua Song, Wei Zhang, Orieta Celiku, Ying Zhang, Jinkyu Jung
Methods of supplementary figures and additional information of materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29145a0973db6af6731fcd569a5f32ef
https://doi.org/10.1158/0008-5472.22422107
https://doi.org/10.1158/0008-5472.22422107