Non-random distribution of deleterious mutations in the DNA and protein-binding domains of IRF6 are associated with Van Der Woude syndrome.

Autor: Alade AA; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA.; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA., Buxo-Martinez CJ; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Mossey PA; Department of Orthodontics, University of Dundee, Dundee, United Kingdom., Gowans LJJ; Komfo Anokye Teaching Hospital and Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Eshete MA; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Adeyemo WL; Department of Oral and Maxillofacial Surgery, University of Lagos, Lagos, Nigeria., Naicker T; School of clinical medicine, KwaZulu-Natal University, Durban, South Africa., Awotoye WA; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Adeleke C; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA., Busch T; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Toraño AM; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Bello CA; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Soto M; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Soto M; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Ledesma R; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Marquez M; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Cordero JF; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Lopez-Del Valle LM; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Salcedo MI; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Debs N; Dental and Craniofacial Genomics Core, University of Puerto Rico School of Dental Medicine, San Juan, Puerto Rico., Li M; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Petrin A; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Olotu J; Department of Anatomy, University of Port Harcourt, Port Harcourt, Nigeria., Aldous C; School of clinical medicine, KwaZulu-Natal University, Durban, South Africa., Olutayo J; Department of Oral and Maxillofacial Surgery, University of Lagos, Lagos, Nigeria., Ogunlewe MO; Department of Oral and Maxillofacial Surgery, University of Lagos, Lagos, Nigeria., Abate F; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Hailu T; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Muhammed I; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Gravem P; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Deribew M; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Gesses M; School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia., Hassan M; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Pape J; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA., Adeniyan OA; NHS Foundation Trust, (Queens Hospital, Burton-On-Trent), Staffordshire, United Kingdom., Obiri-Yeboah S; Komfo Anokye Teaching Hospital and Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Arthur FKN; Komfo Anokye Teaching Hospital and Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Oti AA; Komfo Anokye Teaching Hospital and Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Olatosi O; Department of Child Dental Health, University of Lagos, Nigeria., Miller SE; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA., Donkor P; Komfo Anokye Teaching Hospital and Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Dunnwald MM; Department of Anatomy, University of Iowa, Iowa City, IA, USA., Marazita ML; Oral Biology, Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Adeyemo AA; National Human Genomic Research Institute, Bethesda, MD, USA., Murray JC; Department of Pediatrics, University of Iowa, Iowa City, IA, USA., Butali A; Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.; Iowa Institute of Oral Health Research, University of Iowa, Iowa City, IA, USA.

Publikováno v: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2020 Aug; Vol. 8 (8), pp. e1355. Date of Electronic Publication: 2020 Jun 17.

Oral Health-Related Quality of Life of Children Born With Orofacial Clefts in Ethiopia and Their Parents.

Autor: Abebe ME; 1 Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; 2 Department of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Deressa W; 2 Department of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Oladugba V; 3 Department of Pediatric Dentistry, College of Dentistry, University of Lagos, Nigeria., Owais A; 4 Department of Pediatric Dentistry, College of Dentistry, University of Iowa, Iowa City, IA, USA., Hailu T; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Abate F; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Hailu A; 1 Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Demissie Y; 1 Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Degu S; 6 Dental Department, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Alemayehu B; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Gessesse M; 5 Plastic and Reconstructive Surgery Unit, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia., Deribew M; 1 Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Gravem PE; 7 Department of Plastic and Reconstructive Surgery, Haukeland University Hospital, Bergen, Norway., Mossey P; 8 Department of Orthodontics, University of Dundee, Scotland, United Kingdom., Butali A; 9 Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA.

Publikováno v: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association [Cleft Palate Craniofac J] 2018 Jan 01, pp. 1055665618760619. Date of Electronic Publication: 2018 Jan 01.

A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.

Autor: Leslie EJ; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Liu H; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA; State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China., Carlson JC; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Shaffer JR; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Feingold E; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Wehby G; Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa City, IA 52246, USA., Laurie CA; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Jain D; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Laurie CC; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Doheny KF; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, MD 21224, USA., McHenry T; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Resick J; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Sanchez C; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Jacobs J; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Emanuele B; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Vieira AR; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Neiswanger K; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Standley J; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Czeizel AE; Foundation for the Community Control of Hereditary Diseases, Budapest 1051, Hungary., Deleyiannis F; Department of Surgery, Plastic and Reconstructive Surgery, University of Colorado School of Medicine, Denver, CO 80045, USA., Christensen K; Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense 5230, Denmark., Munger RG; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT 84322, USA., Lie RT; Department of Global Public Health and Primary Care, University of Bergen, Bergen 5020, Norway., Wilcox A; Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Romitti PA; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52246, USA., Field LL; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada., Padilla CD; Institute of Human Genetics, National Institutes of Health, University of the Philippines Manila, Manilla 1000, the Philippines., Cutiongco-de la Paz EM; Institute of Human Genetics, National Institutes of Health, University of the Philippines Manila, Manilla 1000, the Philippines; Department of Pediatrics, College of Medicine, University of the Philippines Manila, Manilla 1000, the Philippines; Philippine Genome Center, University of the Philippines, Manilla 1101, the Philippines., Lidral AC; Department of Orthodontics, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA., Valencia-Ramirez LC; Fundación Clínica Noel, Medellin 050012, Colombia., Lopez-Palacio AM; Department of Basic Integrated Studies, College of Dentistry, University of Antioquia, Medellin 050001, Colombia., Valencia DR; Population Genetics and Mutacarcinogenesis Group, University of Antioquia, Medellin 050001, Colombia., Arcos-Burgos M; Genomics and Predictive Medicine, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT 0200, Australia., Castilla EE; CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics), Rio de Janeiro 21941-617, Brazil., Mereb JC; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at Hospital de Area, El Bolson 8430, Argentina., Poletta FA; CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics), Rio de Janeiro 21941-617, Brazil., Orioli IM; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics), Rio de Janeiro 21941-617, Brazil; Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro 21941-617, Brazil., Carvalho FM; CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil., Hecht JT; Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Blanton SH; Dr. John T. Macdonald Foundation Department of Human Genetics, Hussman Institute for Human Genomics, Mailman School of Medicine, University of Miami, Miami, FL 33124, USA., Buxó CJ; School of Dental Medicine, University of Puerto Rico, San Juan 00936, Puerto Rico., Butali A; Department of Oral Pathology, Radiology and Medicine, Dows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA., Mossey PA; Department of Orthodontics, University of Dundee, Dundee DD1 4HN, Scotland., Adeyemo WL; Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos, P.M.B. 12003, Nigeria., James O; Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos, P.M.B. 12003, Nigeria., Braimah RO; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University Ile-Ife, Ife-Ife, P.M.B. 13, Nigeria., Aregbesola BS; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University Ile-Ife, Ife-Ife, P.M.B. 13, Nigeria., Eshete MA; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia., Deribew M; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia., Koruyucu M; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey., Seymen F; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey., Ma L; School of Stomatology, Peking University, Beijing 100081, China., de Salamanca JE; Hospital Infantil Universitario Niño Jesús, Unidad de Cirugía Plástica, Madrid 28009, Spain., Weinberg SM; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Moreno L; Department of Orthodontics, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA., Cornell RA; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA 52242, USA., Murray JC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Marazita ML; Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Clinical and Translational Science, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address: marazita@pitt.edu.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2016 Apr 07; Vol. 98 (4), pp. 744-54. Date of Electronic Publication: 2016 Mar 24.

Rare functional variants in genome-wide association identified candidate genes for nonsyndromic clefts in the African population.

Autor: Butali A; Department of Oral Pathology, Radiology and Medicine, College of Dentistry University of Iowa, Iowa City, IA., Mossey P, Adeyemo W, Eshete M, Gaines L, Braimah R, Aregbesola B, Rigdon J, Emeka C, Olutayo J, Ogunlewe O, Ladeinde A, Abate F, Hailu T, Mohammed I, Gravem P, Deribew M, Gesses M, Adeyemo A, Marazita M, Murray J

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2014 Oct; Vol. 164A (10), pp. 2567-71. Date of Electronic Publication: 2014 Jul 31.

Novel IRF6 variant in orofacial cleft patients from Durban, South Africa.

Autor: Naicker, Thirona^1,2 (AUTHOR) thironanaicker@gmail.com, Alade, Azeez³ (AUTHOR), Adeleke, Chinyere³ (AUTHOR), Mossey, Peter A.^4,5 (AUTHOR), Awotoye, Waheed A.³ (AUTHOR), Busch, Tamara³ (AUTHOR), Li, Mary³ (AUTHOR), Olotu, Joy⁶ (AUTHOR), Aldous, Colleen⁷ (AUTHOR), Butali, Azeez^3,8 (AUTHOR) azeez‐butali@uiowa.edu

Publikováno v: Molecular Genetics & Genomic Medicine. May2023, Vol. 11 Issue 5, p1-8. 8p.