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of 2
pro vyhledávání: '"Derek Yuan"'
Autor:
Anne T. Truesdale, Octerloney B. McDonald, Byron Ellis, Christopher Pennisi, Edgar R. Wood, David W. Rusnak, Karen Lackey, Scott Howard Dickerson, Krystal J. Alligood, Tona M. Gilmer, Derek Yuan, Lisa M. Shewchuk, Anne M. Hassell, Earnest Horne
Publikováno v:
Cancer Research. 64:6652-6659
GW572016 (Lapatinib) is a tyrosine kinase inhibitor in clinical development for cancer that is a potent dual inhibitor of epidermal growth factor receptor (EGFR, ErbB-1) and ErbB-2. We determined the crystal structure of EGFR bound to GW572016. The c
Autor:
Edgar R, Wood, Anne T, Truesdale, Octerloney B, McDonald, Derek, Yuan, Anne, Hassell, Scott H, Dickerson, Byron, Ellis, Christopher, Pennisi, Earnest, Horne, Karen, Lackey, Krystal J, Alligood, David W, Rusnak, Tona M, Gilmer, Lisa, Shewchuk
Publikováno v:
Cancer research. 64(18)
GW572016 (Lapatinib) is a tyrosine kinase inhibitor in clinical development for cancer that is a potent dual inhibitor of epidermal growth factor receptor (EGFR, ErbB-1) and ErbB-2. We determined the crystal structure of EGFR bound to GW572016. The c