Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Derek Y. Chiang"'
Autor:
Boxi Kang, Jordi Camps, Biao Fan, Hongpeng Jiang, Mahmoud M. Ibrahim, Xueda Hu, Shishang Qin, Dennis Kirchhoff, Derek Y. Chiang, Shan Wang, Yingjiang Ye, Zhanlong Shen, Zhaode Bu, Zemin Zhang, Helge G. Roider
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-25 (2022)
Abstract Background The tumor microenvironment (TME) has been shown to strongly influence treatment outcome for cancer patients in various indications and to influence the overall survival. However, the cells forming the TME in gastric cancer have no
Externí odkaz:
https://doaj.org/article/f607a81be80f4944938163ec4f1a798d
Autor:
Theresa A. Boyle, Gwendolyn P. Quinn, Matthew B. Schabath, Teresita Muñoz‐Antonia, James J. Saller, Luisa F. Duarte, Laura S. Hair, Jamie K. Teer, Derek Y. Chiang, Rebecca Leary, Connie C. Wong, Alexander Savchenko, Angad P. Singh, LaSalette Charette, Kate Mendell, Gullu Gorgun, Scott J. Antonia, Alberto A. Chiappori, Benjamin C. Creelan, Jhanelle E. Gray, Eric B. Haura
Publikováno v:
Cancer Medicine, Vol 9, Iss 1, Pp 225-237 (2020)
Abstract Background For the advancement of cancer research, the collection of tissue specimens from drug‐resistant tumors after targeted therapy is crucial. Although patients with lung cancer are often provided targeted therapy, post‐therapy spec
Externí odkaz:
https://doaj.org/article/82ae3eb5e1ff40e2b1ca8ba0ac5ee571
Autor:
Philip E. Brandish, Michael Rosenzweig, Sheila H. Ranganath, Derek Y. Chiang, Michael Meehl, Chunsheng Zhang, Andrey Loboda, Barbara Joyce-Shaikh, Yujie Qu, Jun Zhang, Peter Stivers, Sarah Javaid, Jeff Grein, Anannya Bhattacharya, Eric S. Muise, Latika Singh
Figure S1A-C - Dot plots and histograms from flow cytometry analysis of SK-MEL-5-educated M-MDSCs and PBMCs cultured in medium alone.Figure S1D - FACS result of cell surface staining of cytokine-induced M-MDSCs and PBMCs cultured in medium alone.Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5680bc3dd085554082920313a25bb51e
https://doi.org/10.1158/1541-7786.22527137
https://doi.org/10.1158/1541-7786.22527137
Autor:
Yao Yao, Yi-Xin Zeng, Hans Bitter, Jeffrey Engelman, Peter S. Hammerman, Glenn Dranoff, Alan Huang, Bin Peng, En Li, Yuanyuan Zhao, Hongyun Zhao, Yan Huang, Wenfeng Fang, Jing Zhang, Peter Skewes-Cox, Lellean JeBailey, Viveksagar Krishnamurthy Radhakrishnan, Savina Jaeger, Yan Wang, Marc Pelletier, Yue Fan, Derek Y. Chiang, Kun Yu, Jason R. Dobson, Chunlin Xin, Pei-Yu Huang, Ting Zhou, Kenzie D. MacIsaac, Li Zhang
Supplementary tables Table S1: Patient characteristics. Table S2: Non-synonymous mutations for paired cohort. Table S3: Non-synonymous mutations for unpaired cohort. Table S4: Copy number variants. Table S5: Correlation of principal components with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b4b408144295ce41b86b706ab72f92
https://doi.org/10.1158/1541-7786.22516114
https://doi.org/10.1158/1541-7786.22516114
Autor:
Yao Yao, Yi-Xin Zeng, Hans Bitter, Jeffrey Engelman, Peter S. Hammerman, Glenn Dranoff, Alan Huang, Bin Peng, En Li, Yuanyuan Zhao, Hongyun Zhao, Yan Huang, Wenfeng Fang, Jing Zhang, Peter Skewes-Cox, Lellean JeBailey, Viveksagar Krishnamurthy Radhakrishnan, Savina Jaeger, Yan Wang, Marc Pelletier, Yue Fan, Derek Y. Chiang, Kun Yu, Jason R. Dobson, Chunlin Xin, Pei-Yu Huang, Ting Zhou, Kenzie D. MacIsaac, Li Zhang
Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV) associated cancer characterized by a poor prognosis and a high level of lymphocyte infiltrate. Genetic hallmarks of NPC are not completely known but include deletion of the p16 (CDKN2A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e754835a8df7589ee647249c5147345b
https://doi.org/10.1158/1541-7786.c.6541285
https://doi.org/10.1158/1541-7786.c.6541285
Autor:
Philip E. Brandish, Michael Rosenzweig, Sheila H. Ranganath, Derek Y. Chiang, Michael Meehl, Chunsheng Zhang, Andrey Loboda, Barbara Joyce-Shaikh, Yujie Qu, Jun Zhang, Peter Stivers, Sarah Javaid, Jeff Grein, Anannya Bhattacharya, Eric S. Muise, Latika Singh
Table S1 - Antibodies used for flow cytometry-based assessment of binding of anti-ILT3 and anti-ILT4 antibody to human primary cells and SK-MEL-5-educated monocytic myeloid-derived suppressor cells.Table S2 - Antibodies used for flow cytometry-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b43a9c750193748d4be38bebf5f796
https://doi.org/10.1158/1541-7786.22527134.v1
https://doi.org/10.1158/1541-7786.22527134.v1
Autor:
Elaine M. Pinheiro, Terrill K. McClanahan, Brian J. Long, Svetlana Sadekova, Razvan Cristescu, Andrey Loboda, Derek Y. Chiang, Lily Y. Moy, Aleksandra K. Olow, Sarah Javaid, Heather A. Hirsch, Kimberly S. Kerr, Wendy M. Blumenschein, Manjiri Sathe, Michael Nebozhyn, Venkataraman Sriram, Jennifer H. Yearley, Hui Xiao, Lan Chen, Michael Caniga, Selvakumar Sukumar, Douglas C. Wilson, Louise Cadzow, Mingmei Cai, Yun Wang, Marlene C. Hinton, Douglas E. Linn, Eric S. Muise, Peter Georgiev
Targeting the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell–inflamed gene expression profile (GEP) are clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdb5d08b628c9801815bfadb0bfe628
https://doi.org/10.1158/1535-7163.c.6543385.v1
https://doi.org/10.1158/1535-7163.c.6543385.v1
Autor:
Philip E. Brandish, Michael Rosenzweig, Sheila H. Ranganath, Derek Y. Chiang, Michael Meehl, Chunsheng Zhang, Andrey Loboda, Barbara Joyce-Shaikh, Yujie Qu, Jun Zhang, Peter Stivers, Sarah Javaid, Jeff Grein, Anannya Bhattacharya, Eric S. Muise, Latika Singh
Figure S1A-C - Dot plots and histograms from flow cytometry analysis of SK-MEL-5-educated M-MDSCs and PBMCs cultured in medium alone.Figure S1D - FACS result of cell surface staining of cytokine-induced M-MDSCs and PBMCs cultured in medium alone.Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5e51a1b27a3b58d346116598087f8a
https://doi.org/10.1158/1541-7786.22527140
https://doi.org/10.1158/1541-7786.22527140
Autor:
Philip E. Brandish, Michael Rosenzweig, Sheila H. Ranganath, Derek Y. Chiang, Michael Meehl, Chunsheng Zhang, Andrey Loboda, Barbara Joyce-Shaikh, Yujie Qu, Jun Zhang, Peter Stivers, Sarah Javaid, Jeff Grein, Anannya Bhattacharya, Eric S. Muise, Latika Singh
Myeloid-derived suppressor cells (MDSC) are immature myeloid cells that accumulate in the tumor microenvironment (TME). MDSCs have been shown to dampen antitumor immune responses and promote tumor growth; however, the mechanisms of MDSC induction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f008466de2fc3983a89a5cb1fb28a943
https://doi.org/10.1158/1541-7786.c.6545345.v1
https://doi.org/10.1158/1541-7786.c.6545345.v1
Autor:
Elaine M. Pinheiro, Terrill K. McClanahan, Brian J. Long, Svetlana Sadekova, Razvan Cristescu, Andrey Loboda, Derek Y. Chiang, Lily Y. Moy, Aleksandra K. Olow, Sarah Javaid, Heather A. Hirsch, Kimberly S. Kerr, Wendy M. Blumenschein, Manjiri Sathe, Michael Nebozhyn, Venkataraman Sriram, Jennifer H. Yearley, Hui Xiao, Lan Chen, Michael Caniga, Selvakumar Sukumar, Douglas C. Wilson, Louise Cadzow, Mingmei Cai, Yun Wang, Marlene C. Hinton, Douglas E. Linn, Eric S. Muise, Peter Georgiev
Supplementary Data from Reverse Translating Molecular Determinants of Anti–Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681228ea71eeffe6a5d955b9c8768f68
https://doi.org/10.1158/1535-7163.22522450
https://doi.org/10.1158/1535-7163.22522450