Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Derek Wong"'
Autor:
Derek Wong, Maha Tageldein, Ping Luo, Erik Ensminger, Jeffrey Bruce, Leslie Oldfield, Haifan Gong, Nicholas William Fischer, Brianne Laverty, Vallijah Subasri, Scott Davidson, Reem Khan, Anita Villani, Adam Shlien, Raymond H. Kim, David Malkin, Trevor J. Pugh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Germline pathogenic TP53 variants predispose individuals to a high lifetime risk of developing multiple cancers and are the hallmark feature of Li-Fraumeni syndrome (LFS). Our group has previously shown that LFS patients harbor shorter plasm
Externí odkaz:
https://doaj.org/article/91f463f696dc4e2f80c0b454ddff5916
Autor:
Haley Newman, Mary Egan Clark, Derek Wong, Jinhua Wu, Garrett M Brodeur, Stephen P Hunger, Sarah K Tasian, Timothy Olson, Julia T. Warren, David T Teachey, Kira Bona, Jeffrey Schubert, Netta Golenberg, Maha Patel, Elizabeth H Denenberg, Elizabeth A Fanning, Jiani Chen, Tamara Luke, Sarah Charles, Daniel Gallo, Kajia Cao, Weixuan Fu, Zhiqian Fan, Lea F Surrey, Gerald Wertheim, Minjie Luo, Suzanne P MacFarland, Marilyn M Li, Yiming Zhong
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/39f2d8cef8eb498bb68523732629bf05
Autor:
Robert Gilchrist, Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Kim Lynn-Jee, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden A Homer, Lindsay E Wu
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 518-518 (2023)
Background and Aims: Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive, pharmacological approaches to prevent chemotherapy induced infertility are u
Externí odkaz:
https://doaj.org/article/34e09bb2cf2c4adf92b3339f6ca9ecaf
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Diffusely infiltrative low-grade gliomas (LGG) are primary brain tumours that arise predominantly in the cerebral hemispheres of younger adults. LGG can display either astrocytic or oligodendroglial histology and do not express malignant his
Externí odkaz:
https://doaj.org/article/a67319063b3c4edb92b7e5841436e309
Autor:
Derek Wong, Ping Luo, Stephanie Pederson, Clarissa Chan, Kirsten Farncombe, Maia Norman, Leslie E. Oldfield, Raymond Kim, Trevor Pugh
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100106- (2023)
Externí odkaz:
https://doaj.org/article/59b6a2c2aa164ba9a9817b0a20710bde
Publikováno v:
Journal of Learning Development in Higher Education, Iss 24 (2022)
In Covid-19’s ‘new normal’ academics have been urged to tear down subject silos and approach teaching collaboratively with renewed interest and increased urgency. An example of this can be found in curriculum-integrated academic literacy instru
Externí odkaz:
https://doaj.org/article/7b990d721f9442a9a94f4e66df3c47b4
Autor:
Shikha Saxena, PhD, Jamie Millage, BA, Derek Wong, MD, Li-Ann Yap, MBA, Lorene Bodiam, Archie Allison, Brian W. McCrindle, MD, Patricia E. Longmuir, PhD
Publikováno v:
CJC Open, Vol 3, Iss 7, Pp 854-863 (2021)
Background: Children with complex heart problems may be at higher risk for sedentary lifestyle morbidities than their healthy peers. This project examined perceptions, barriers, and supports that influence healthy active lifestyles among children wit
Externí odkaz:
https://doaj.org/article/1755654a806b4a14ba0c171ab58a5c66
Autor:
Derek Wong, Lisa Sogerer, Samantha S. Lee, Victor Wong, Amy Lum, Adrian B. Levine, Marco A. Marra, Stephen Yip
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Aberrations in Capicua (CIC) have recently been implicated as a negative prognostic factor in a multitude of cancer types through the derepression of targets downstream of the mitogen-activated protein kinase (MAPK) signaling casc
Externí odkaz:
https://doaj.org/article/bb8ef9269ef84a15aa79c7b42e24e8e5
Autor:
Yue Huang, Rajesh Sharma, Annette Feigenbaum, Chung Lee, Inderneel Sahai, Rossana Sanchez Russo, Juanita Neira, Susan Sklower Brooks, Kelly E. Jackson, Derek Wong, Stephen Cederbaum, Felicitas L. Lacbawan, Charles M. Rowland, Pranoot Tanpaiboon, Denise Salazar
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 27, Iss , Pp 100735- (2021)
Arginase deficiency is a rare inborn error of metabolism that interrupts the final step of the urea cycle. Untreated individuals often present with episodic hyperammonemia, developmental delay, cognitive impairment, and spasticity in early childhood.
Externí odkaz:
https://doaj.org/article/3bd6b55f70134d4d897f63c7b81b6687
Autor:
Nikita Patel, Juehong Wang, Kumiko Shiozawa, Kevin B. Jones, Yanfeng Zhang, Jeremy W. Prokop, George G. Davenport, Naoe T. Nihira, Zhenyue Hao, Derek Wong, Laurel Brandsmeier, Sarah K. Meadows, Arthur V. Sampaio, Ryan Vander Werff, Makoto Endo, Mario R. Capecchi, Kelly M. McNagny, Tak W. Mak, Torsten O. Nielsen, T. Michael Underhill, Richard M. Myers, Tadashi Kondo, Le Su
Publikováno v:
iScience, Vol 13, Iss , Pp 43-54 (2019)
Summary: Histone deacetylases (HDACs) are promising targets for cancer therapy, although their individual actions remain incompletely understood. Here, we identify a role for HDAC2 in the regulation of MDM2 acetylation at previously uncharacterized l
Externí odkaz:
https://doaj.org/article/86168b789a6f460780d4cbfa71bccd3c