Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Derek Walsh"'
Autor:
Nathan Meade, Helen K. Toreev, Ram P. Chakrabarty, Charles R. Hesser, Chorong Park, Navdeep S. Chandel, Derek Walsh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Poxviruses are unusual DNA viruses that replicate in the cytoplasm. To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS) along with several other antiv
Externí odkaz:
https://doaj.org/article/10cdeac366b04e5c96ee9f6eb5cecfe9
Autor:
Felicia Goodrum, Anice C. Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Michael J. Imperiale, Walter Atwood, Daphne Avgousti, Joel Baines, Bruce Banfield, Lawrence Banks, Sumita Bhaduri-McIntosh, Deepta Bhattacharya, Daniel Blanco-Melo, David Bloom, Adrianus Boon, Steeve Boulant, Curtis Brandt, Andrew Broadbent, Christopher Brooke, Craig Cameron, Samuel Campos, Patrizia Caposio, Gary Chan, Anna Cliffe, John Coffin, Kathleen Collins, Blossom Damania, Matthew Daugherty, Kari Debbink, James DeCaprio, Terence Dermody, Jimmy Dikeakos, Daniel DiMaio, Rhoel Dinglasan, W. Paul Duprex, Rebecca Dutch, Nels Elde, Michael Emerman, Lynn Enquist, Bentley Fane, Ana Fernandez-Sesma, Michelle Flenniken, Lori Frappier, Matthew Frieman, Klaus Frueh, Michaela Gack, Marta Gaglia, Tom Gallagher, Denise Galloway, Adolfo García-Sastre, Adam Geballe, Britt Glaunsinger, Stephen Goff, Alexander Greninger, Meaghan Hancock, Eva Harris, Nicholas Heaton, Mark Heise, Ekaterina Heldwein, Brenda Hogue, Stacy Horner, Edward Hutchinson, Joseph Hyser, William Jackson, Robert Kalejta, Jeremy Kamil, Stephanie Karst, Frank Kirchhoff, David Knipe, Timothy Kowalik, Michael Lagunoff, Laimonis Laimins, Ryan Langlois, Adam Lauring, Benhur Lee, David Leib, Shan-Lu Liu, Richard Longnecker, Carolina Lopez, Micah Luftig, Jennifer Lund, Balaji Manicassamy, Grant McFadden, Michael McIntosh, Andrew Mehle, W. Allen Miller, Ian Mohr, Cary Moody, Nathaniel Moorman, Anne Moscona, Bryan Mounce, Joshua Munger, Karl Münger, Eain Murphy, Mojgan Naghavi, Jay Nelson, Christopher Neufeldt, Janko Nikolich, Christine O'Connor, Akira Ono, Walter Orenstein, David Ornelles, Jing-hsiung Ou, John Parker, Colin Parrish, Andrew Pekosz, Philip Pellett, Julie Pfeiffer, Richard Plemper, Stephen Polyak, John Purdy, Dohun Pyeon, Miguel Quinones-Mateu, Rolf Renne, Charles Rice, John Schoggins, Richard Roller, Charles Russell, Rozanne Sandri-Goldin, Martin Sapp, Luis Schang, Scott Schmid, Stacey Schultz-Cherry, Bert Semler, Thomas Shenk, Guido Silvestri, Viviana Simon, Gregory Smith, Jason Smith, Katherine Spindler, Megan Stanifer, Kanta Subbarao, Wesley Sundquist, Mehul Suthar, Troy Sutton, Andrew Tai, Vera Tarakanova, Benjamin tenOever, Scott Tibbetts, Stephen Tompkins, Zsolt Toth, Koenraad van Doorslaer, Marco Vignuzzi, Nicholas Wallace, Derek Walsh, Michael Weekes, Jason Weinberg, Matthew Weitzman, Sandra Weller, Sean Whelan, Elizabeth White, Bryan Williams, Christiane Wobus, Scott Wong, Andrew Yurochko
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease burden with vaccines an
Externí odkaz:
https://doaj.org/article/88d633fd96714f98a0ed8b9526e9581b
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 269-283.e6 (2020)
Summary: End-binding proteins (EBs) are widely viewed as master regulators of microtubule dynamics and function. Here, we show that while EB1 mediates the dynamic microtubule capture of herpes simplex virus type 1 (HSV-1) in fibroblasts, in neuronal
Externí odkaz:
https://doaj.org/article/bb0d8727559c41c9a62207c437241356
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1249-1258 (2018)
Summary: Post-translational modification of ribosomal subunit proteins (RPs) is emerging as an important means of regulating gene expression. Recently, regulatory ubiquitination of small RPs RPS10 and RPS20 by the ubiquitin ligase ZNF598 was found to
Externí odkaz:
https://doaj.org/article/1cd7b92e984c4877a87550a20df5c6f2
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
HIV infection results in elevated beta-amyloid (Aβ) levels in the brain, but the underlying mechanisms are unclear. Here, the authors show that amyloid precursor protein inhibits virion production and that HIV Gag, counteracting this antiviral funct
Externí odkaz:
https://doaj.org/article/4bb6852761304008b18756776bcceede
Autor:
Derek Walsh
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006832 (2018)
[This corrects the article DOI: 10.1371/journal.ppat.1006634.].
Externí odkaz:
https://doaj.org/article/be81d966d2e44c5382e8fc1eaebb3004
Autor:
Derek Walsh
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006634 (2017)
Externí odkaz:
https://doaj.org/article/32859cf59229446ea0660ddcc086ceca
Autor:
Qingqing Chai, Vladimir Jovasevic, Viacheslav Malikov, Yosef Sabo, Scott Morham, Derek Walsh, Mojgan H. Naghavi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the Methods section ‘Viruses and drugs’. The timing for drug treatment of CHME3 4 × 4 or 293T cells with γ-secretase inhibitor or BACE1 inhibitor was incorrectly given as ‘1 day prior
Externí odkaz:
https://doaj.org/article/6c026654b4044287a63e0ddea5d16de2
Publikováno v:
PLoS Pathogens, Vol 5, Iss 3, p e1000334 (2009)
In response to numerous signals, latent herpesvirus genomes abruptly switch their developmental program, aborting stable host-cell colonization in favor of productive viral replication that ultimately destroys the cell. To achieve a rapid gene expres
Externí odkaz:
https://doaj.org/article/808210fb90214ee196e130090c3ffce2
Autor:
Charles R. Hesser, Derek Walsh
Publikováno v:
Journal of Virology. 97
There is increasing recognition of the importance of N 6 -methyladenosine (m 6 A) modifications to both viral and host mRNAs and the complex roles this modification plays in determining the fate of infection by diverse RNA and DNA viruses. However, i