Výsledky vyhledávání - "Derek W. Linskey"

The need to shift pharmacogenetic research from candidate gene to genome-wide association studies

Autor: David C Linskey, Derek W. Linskey, Howard L. McLeod, Jasmine A. Luzum

Publikováno v: Pharmacogenomics

The primary research approach in pharmacogenetics has been candidate gene association studies (CGAS), but pharmacogenomic genome-wide association studies (GWAS) are becoming more common. We are now at a critical juncture when the results of those two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9101b20c4907f692d62e584653b865f
https://doi.org/10.2217/pgs-2021-0108

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Association of SLCO1B1 c.521TC (rs4149056) with discontinuation of atorvastatin due to statin-associated muscle symptoms

Autor: Daniel A. Perry, Georgirene D. Vladutiu, Chang-Xing Ma, Derek W. Linskey, Paul J. Isackson, Heather M. Ochs-Balcom, Joseph D. English, Jasmine A. Luzum

Publikováno v: Pharmacogenet Genomics

The most common adverse drug reaction from statins are statin-associated muscle symptoms (SAMS), characterized by myopathy (weakness), myalgia (muscle pain), and commonly elevation in serum creatine kinase. All statins are substrates of the organic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b363f5ce202c4110dcc9b61c02746b
https://pubmed.ncbi.nlm.nih.gov/32453264

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