Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Derek V. Gardner"'
Autor:
Derek V. Gardner, Trevor J. White, Frank E. Blaney, Michael S. G. Clark, Michael S. Hadley, David Middleton
Publikováno v:
Journal of Medicinal Chemistry. 26:1747-1752
The substituted benzamides are used clinically both as antipsychotics and as stimulants of gastric motility. The antipsychotic effects are considered to be a consequence of their central dopamine antagonist properties, but there is evidence that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f945d156d0cb55870041a4a6bb216b9
https://doi.org/10.1021/jm00366a017
https://doi.org/10.1021/jm00366a017
Autor:
David Miller, Derek V. Gardner
Publikováno v:
Journal of Heterocyclic Chemistry. 21:121-127
Analogues of the cannabinoid-like anti-emetic nonabine (BRL 4664), in which the 4-pyridinyl and 1,2-dimethylheptyl groups have been replaced by other aryl and alky groups respectively, have been synthesised from the appropriate resorcinol by a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067be19d39f5fb2c3f2c4355caff9d36
https://doi.org/10.1002/jhet.5570210125
https://doi.org/10.1002/jhet.5570210125
Publikováno v:
The Journal of Organic Chemistry. 49:3887-3891
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070bce56a0da4f917929a5c8101b8a0b
https://doi.org/10.1021/jo00195a003
https://doi.org/10.1021/jo00195a003
Autor:
Judith A. Clark, Michael S. G. Clark, Michael S. Hadley, Derek V. Gardner, Laramie Mary Gaster, Anwer Shah, David Miller
Publikováno v:
Journal of Medicinal Chemistry. 22:1373-1379
Following the discovery that 3-(dimethylamino)-1,1-diphenyl-2-propanol hydrobromide (1) possesses potent reserpine-prevention activity in mice, a series of analogues of 1 was synthesized and evaluated as potential antidepressant agents. Several route
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262843a6856e965d4d775470c9efe3bf
https://doi.org/10.1021/jm00197a018
https://doi.org/10.1021/jm00197a018
Publikováno v:
J. Chem. Soc., Chem. Commun.. :807-809
Application of tricarbonyl (2-methoxycyclohexadienylium)iron hexafluorophosphate (4) as a readily available synthetic equivalent of the p-methoxyphenyl cation is exploited in a synthetic approach to the sceletium alkaloid (±)-O-methyljoubertiamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31a432958d7c9bcdb7cf60c55ee9f1be
https://doi.org/10.1039/c39820000807
https://doi.org/10.1039/c39820000807
Publikováno v:
Chemischer Informationsdienst. 13
Application of tricarbonyl (2-methoxycyclohexadienylium)iron hexafluorophosphate (4) as a readily available synthetic equivalent of the p-methoxyphenyl cation is exploited in a synthetic approach to the sceletium alkaloid (±)-O-methyljoubertiamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01439eb6258f61179c48111e65a8f4be
https://doi.org/10.1002/chin.198250328
https://doi.org/10.1002/chin.198250328
Autor:
Michael S. Hadley, Frank E. Blaney, Michael S. G. Clark, David Middleton, Derek V. Gardner, Trevor J. White
Publikováno v:
Chemischer Informationsdienst. 15
The substituted benzamides are used clinically both as antipsychotics and as stimulants of gastric motility. The antipsychotic effects are considered to be a consequence of their central dopamine antagonist properties, but there is evidence that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5447f014c306620ac97d3b70f5fe629
https://doi.org/10.1002/chin.198418229
https://doi.org/10.1002/chin.198418229