Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Derek Rowter"'
Publikováno v:
Methods in cell biology. 171
The heterogeneity of breast tumors is a major factor in the development, progression, and therapeutic response of breast cancer. In terms of therapy resistance, a subset of tumor cells commonly referred to as cancer stem cells (CSCs) or tumor initiat
Publikováno v:
Methods in Cell Biology ISBN: 9780323900188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e96cfba0321172b8a372cf91e11a680
https://doi.org/10.1016/bs.mcb.2022.04.006
https://doi.org/10.1016/bs.mcb.2022.04.006
Autor:
Lauren P. Westhaver, Sarah Nersesian, Adam Nelson, Leah K. MacLean, Emily B. Carter, Derek Rowter, Jun Wang, Boris L. Gala-Lopez, Andrew W. Stadnyk, Brent Johnston, Jeanette E. Boudreau
Publikováno v:
Cell reports. 39(8)
Tissue damage leads to loss of cellular and mitochondrial membrane integrity and release of damage-associated molecular patterns, including those of mitochondrial origin (mitoDAMPs). Here, we describe the lymphocyte response to mitoDAMPs. Using prima
Publikováno v:
Clinical Immunology. 161:373-383
Intravenous IgG (IVIG) therapy can be used for immunomodulation. IL-2 is an immunoregulatory cytokine. We evaluated IVIG modulation of human blood lymphocyte response to IL-2 and other cytokines. Neither IVIG nor low concentrations of IL-2 (3-30U/ml)
Autor:
Patrick J. Quinn, Derek Rowter, Suzanne E. Ramsey, Adam M. Huber, Bianca Lang, Thomas B. Issekutz, Andrew C. Issekutz, Mohan Karkada
Publikováno v:
Arthritis & Rheumatism. 63:3467-3476
Objective To investigate P- and E-selectin ligand coexpression with chemokine receptors (CKRs) on T cells in the synovial fluid (SF) and blood of children with juvenile idiopathic arthritis (JIA). Methods Sixteen patients with polyarticular or persis
Publikováno v:
Clinical immunology (Orlando, Fla.). 160(2)
IVIG modulates T cell activation in vitro and inflammatory-autoimmune conditions in vivo. Sialylation of IgG, Fc receptor interactions, modulation of monocyte/macrophage/B cell functions have been implicated in IVIG effects. Subcutaneous IgG (SCIG) t
Publikováno v:
Clinical immunology (Orlando, Fla.). 141(2)
High-dose intravenous immunoglobulin (IVIG) has anti-inflammatory effects via incompletely understood mechanisms. By investigating whether IVIG might modulate neutrophil (PMN) recruitment, we observed that IVIG dose-dependently inhibited (by 30-50%)
Autor:
Andrew C. Issekutz, Ayham Al-Afif, Robert Anderson, Jean S. Marshall, Michael G. Brown, Derek Rowter, Laura L. Hermann
Publikováno v:
Journal of virology. 85(2)
Vascular perturbation is a hallmark of severe forms of dengue disease. We show here that antibody-enhanced dengue virus infection of primary human cord blood-derived mast cells (CBMCs) and the human mast cell-like line HMC-1 results in the release of
Intravenous immunoglobulin G selectively inhibits IL-1α-induced neutrophil-endothelial cell adhesion
Publikováno v:
Autoimmunity. 43(8)
Intravenous immunoglobulin (IVIG) G at high doses has therapeutic benefits in a variety of autoimmune and inflammatory disorders. The mechanism by which IVIG modulates inflammation is incompletely understood. We tested the hypothesis that IVIG modula
Publikováno v:
Experimental lung research. 32(10)
Within the alveolus, epithelial cells, due to their close association with endothelial cells, can potentially influence endothelial cell responsiveness during inflammation and their interaction with leukocytes. To investigate this, three lung epithel