Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Derek Reichel"'
Autor:
Ji Eun Park, Se-Eun Chun, Derek Reichel, Jee Sun Min, Su-Chan Lee, Songhee Han, Gongmi Ryoo, Yunseok Oh, Shin-Hyung Park, Heon-Min Ryu, Kyung Bo Kim, Ho-Young Lee, Soo Kyung Bae, Younsoo Bae, Wooin Lee
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173247 (2017)
Carfilzomib (CFZ) is a peptide epoxyketone proteasome inhibitor approved for the treatment of multiple myeloma (MM). Despite the remarkable efficacy of CFZ against MM, the clinical trials in patients with solid cancers yielded rather disappointing re
Externí odkaz:
https://doaj.org/article/84712ebbc6e04ef68bd9e82f610f0fbf
Autor:
J. Manuel Perez, John S. Yu, Hongqiang Wang, James Teh, Leland W.K. Chung, Keith L. Black, Yi Zhang, Derek Reichel, Bien Sagong, Shawn Wagner, Pramod Butte
Publikováno v:
ACS Nano
Despite significant efforts to improve glioblastoma multiforme (GBM) treatment, GBM remains one of the most lethal cancers. Effective GBM treatments require sensitive intraoperative tumor visualization and effective postoperative chemotherapeutic del
Autor:
Nicholas A. Bernier, Joanne Zahorsky-Reeves, James Teh, Alexander M. Spokoyny, Derek Reichel, J. Manuel Perez
Publikováno v:
Langmuir
Host-guest interactions represent a growing research area with recent work demonstrating the ability to chemically manipulate both host molecules as well as guest molecules to vary the type and strength of bonding. Much less is known about the intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2bd197a222a4b78f96982367ca71d5
https://doi.org/10.26434/chemrxiv-2021-79b8f
https://doi.org/10.26434/chemrxiv-2021-79b8f
Autor:
Younsoo Bae, Yunfei Li, Yajuan Xiao, Derek Reichel, Hsuan-Pei Lin, Yiguo Jiang, Chengfeng Yang, Xuefei Huang, Eun Y. Lee, Zhishan Wang
Publikováno v:
Biomaterials. 188:160-172
Cancer stem cells (CSCs) play pivotal roles in cancer metastasis, and strategies targeting cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The canonical Wnt/β-catenin pathway plays critical roles in CSC generatio
Autor:
Wafa Tawackoli, Tina Stefanovic, Pablo Avalos, Derek Reichel, Thomas J. Kremen, Manuel J. Perez, Juliane D. Glaeser, Dmitriy Sheyn, Khosrowdad Salehi
Publikováno v:
Am J Sports Med
Background: There is a high incidence of posttraumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) injury, and these injuries represent an enormous health care economic burden. In an effort to address this unmet clinical need, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cbd9f975b429f8b690975c091868ee
https://europepmc.org/articles/PMC7945314/
https://europepmc.org/articles/PMC7945314/
Autor:
Bien Sagong, Derek Reichel, J. Manuel Perez, Manisha Tripathi, James Teh, Ricardo Montoya, Yi Zhang, Leland W.K. Chung, Rola Saouaf, Shawn Wagner
Publikováno v:
Nanotheranostics
Successful visualization of prostate cancer (PCa) tumor margins during surgery remains a major challenge. The visualization of these tumors during surgery via near infrared fluorescence (NIRF) imaging would greatly enhance surgical resection, minimiz
Autor:
Derek Reichel, Louis T. Curtis, Elizabeth Ehlman, B. Mark Evers, Piotr Rychahou, Hermann B. Frieboes, Younsoo Bae
Publikováno v:
Pharmaceutical Research. 38:1467-1467
Autor:
Younsoo Bae, Piotr G. Rychahou, Derek Reichel, Steven Rheiner, Hsin-Sheng Yang, Tadahide Izumi
Publikováno v:
International Journal of Pharmaceutics. 528:536-546
Poly(ethylene glycol)-conjugated polyethylenimine (PEG-PEI) is a widely studied cationic polymer used to develop non-viral vectors for siRNA therapy of genetic disorders including cancer. Cell lines stably expressing luciferase reporter protein typic
Publikováno v:
Nanotheranostics
Purpose: A successful cancer surgery requires the complete removal of cancerous tissue, while also sparing as much healthy, non-cancerous tissue as possible. To achieve this, an accurate identification of tumor boundaries during surgery is critical,
Autor:
Younsoo Bae, Derek Reichel
Publikováno v:
Pharmaceutical Research. 34:394-407
To compare traditional dialysis- and novel solvatofluorochromism (SFC)-based methods for accurate determination of drug release profiles for nanoparticle drug carriers. Polymer nanoassemblies (PNAs) varying in drug release patterns were prepared usin