Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Derek R. Van Lonkhuyzen"'
Publikováno v:
Cytokine & Growth Factor Reviews. 52:45-55
Chronic exposure of human skin to solar ultraviolet radiation (UVR) induces a range of biological reactions which may directly or indirectly lead to the development of skin cancer. In order to overcome these damaging effects of UVR and to reduce phot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74fc4cd1e3f833db16cd87c1edc3835
https://doi.org/10.1016/j.cytogfr.2019.11.004
https://doi.org/10.1016/j.cytogfr.2019.11.004
Publikováno v:
Journal of Cell Science. 134
UVBR-induced photolesions in genomic DNA of keratinocytes impair cellular functions and potentially determine the cell fate post-irradiation. The ability of insulin-like growth factor-I (IGF-I) to rescue epidermal keratinocytes after photodamage via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b1bd54780688263068999c43b14d05
https://doi.org/10.1242/jcs.255786
https://doi.org/10.1242/jcs.255786
Autor:
Joan Röhl, Andreea Zaharia, Zoe Elizabeth West, Derek R. Van Lonkhuyzen, Maren Rudolph, Rachael Z. Murray, Danica K. Hickey, A Semmler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d7fa4a4a4646be2012cac9a78e7bdb
https://doi.org/10.1111/tra.12675/v2/response1
https://doi.org/10.1111/tra.12675/v2/response1
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 209:111951
Ultraviolet B radiation (UVBR) induces the formation of photolesions in epidermal keratinocytes, potentially affecting cellular function and contributing towards malignant transformation. Insulin-like growth factor-I (IGF-I) contributes to protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd30198f253fa37c85a53837c5dca24
https://doi.org/10.1016/j.jphotobiol.2020.111951
https://doi.org/10.1016/j.jphotobiol.2020.111951
Autor:
Andreea Zaharia, A Semmler, Maren Rudolph, Zoe Elizabeth West, Danica K. Hickey, Derek R. Van Lonkhuyzen, Rachael Z. Murray, Joan Röhl
Publikováno v:
Traffic (Copenhagen, Denmark)REFERENCES. 20(9)
Macrophage migration into injured or infected tissue is a key aspect in the pathophysiology of many diseases where inflammation is a driving factor. Membrane-type-1 matrix metalloproteinase (MT1-MMP) cleaves extracellular matrix components to facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650a7f2564f275b5da22daad9cce0cc4
https://pubmed.ncbi.nlm.nih.gov/31297933
https://pubmed.ncbi.nlm.nih.gov/31297933
Publikováno v:
Photochemistry and Photobiology. 90:1332-1339
Exposure to ultraviolet radiation is closely linked to the development of skin cancers in humans. The ultraviolet B (UVB) radiation wavelength (280-320 nm), in particular, causes DNA damage in epidermal keratinocytes, which are linked to the generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce484606f4c126d79dc52b3d0eb84a3
https://doi.org/10.1111/php.12317
https://doi.org/10.1111/php.12317
Publikováno v:
Tissue Engineering Part C: Methods. 20:588-598
The incidences of skin cancers resulting from chronic ultraviolet radiation (UVR) exposure are on the incline in both Australia and globally. Hence, the cellular and molecular pathways that are associated with UVR-induced photocarcinogenesis need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530f8b94948f6f4ab8f0a1edbdb9932c
https://doi.org/10.1089/ten.tec.2013.0293
https://doi.org/10.1089/ten.tec.2013.0293
Autor:
Gary K. Shooter, Derek R. Van Lonkhuyzen, Keith Harding, Pat Aldons, Michael Stacey, Helen Edwards, Eva-Lisa Heinrichs, Michelle Gibb, Emily Lynam, Zee Upton, Kathleen Finlayson, Liz Jenkins
Publikováno v:
International Wound Journal. 11:129-137
Hard-to-heal leg ulcers are a major cause of morbidity in the elderly population. Despite improvements in wound care, some wounds will not heal and they present a significant challenge for patients and health care providers. A multi-centre cohort stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a36177f55f2f396bfbca4de010d9c31
https://doi.org/10.1111/iwj.12115
https://doi.org/10.1111/iwj.12115
Publikováno v:
Journal of biomolecular structuredynamics. 35(4)
The insulin receptor (IR) plays critical roles in metabolism and growth, directed by the binding of insulin. Decades of research to understand the mechanism of insulin binding and activation of the IR have identified a region of the receptor, the C-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945e95e9799c9aca195b173be4004323
https://pubmed.ncbi.nlm.nih.gov/27137342
https://pubmed.ncbi.nlm.nih.gov/27137342
A tan in a test tube -in vitro models for investigating ultraviolet radiation-induced damage in skin
Publikováno v:
Experimental Dermatology. 21:404-410
Free to read Presently, global rates of skin cancers induced by ultraviolet radiation (UVR) exposure are on the rise. In view of this, current knowledge gaps in the biology of photocarcinogenesis and skin cancer progression urgently need to be addres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f5d09efe89ff2504c617af64749b99
https://doi.org/10.1111/j.1600-0625.2012.01485.x
https://doi.org/10.1111/j.1600-0625.2012.01485.x