Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Derek R, Boyd"'
Autor:
Derek R. Boyd, Narain D. Sharma, Pui L. Loke, Jonathan G. Carroll, Paul J. Stevenson, Patrick Hoering, Christopher C. R. Allen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Molecular docking studies of quinoline and 2-chloroquinoline substrates at the active site of toluene dioxygenase (TDO), were conducted using Autodock Vina, to identify novel edge-to-face interactions and to rationalize the observed stereoselective c
Externí odkaz:
https://doaj.org/article/b3a14fd3cfda44f0bb47e8ad3393a055
Autor:
Derek R. Boyd, Narain D. Sharma, Paul J. Stevenson, Patrick Hoering, Christopher C. R. Allen, Patrick M. Dansette
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 909 (2022)
Enzymatic oxidations of thiophenes, including thiophene-containing drugs, are important for biodesulfurization of crude oil and drug metabolism of mono- and poly-cyclic thiophenes. Thiophene oxidative dearomatization pathways involve reactive metabol
Externí odkaz:
https://doaj.org/article/547e6af72fd14aac9c97bb5652f8941e
Autor:
Derek R. Boyd, Christopher J. McGivern, Christopher C. R. Allen, Patrick Hoering, Narain D. Sharma, Paul J. Stevenson
Publikováno v:
Boyd, D R, Sharma, N D, McGivern, C J, Stevenson, P J, Hoering, P & Allen, C C R 2019, ' Chemoenzymatic Synthesis of (-)-Ribisins A and B from Dibenzo[b,d]furan ', Journal of Organic Chemistry, vol. 84, pp. 15165-15172 . https://doi.org/10.1021/acs.joc.9b02171
cis-Dihydrodiols, derived from monocyclic aromatic compounds, are valuable chiral pool intermediates for the synthesis of cyclic natural products. A drawback of this approach, to the synthesis of polycyclic secondary metabolites, is that additional r
Autor:
Derek R. Boyd, Narain D. Sharma, Nuala A. Kerley, Gareth McConville, Christopher C. R. Allen, A. John Blacker
Publikováno v:
ARKIVOC, Vol 2003, Iss 7, Pp 32-48 (2003)
Externí odkaz:
https://doaj.org/article/b41794a26a4c46169d1f16f4140b2c86
Autor:
Patrick Hoering, Jonathan G. Carroll, Derek R. Boyd, Paul J. Stevenson, Pui L. Loke, Christopher C. R. Allen, Narain D. Sharma
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Boyd, D, Das Sharma, N, Loke, P L, Carroll, J G, Stevenson, P, Hoering, P & Allen, C C R 2021, ' Toluene Dioxygenase-Catalyzed cis-Dihydroxylation of Quinolines: A Molecular Docking Study and Chemoenzymatic Synthesis of Quinoline Arene Oxides ', Frontiers in Bioengineering and Biotechnology . https://doi.org/10.3389/fbioe.2020.619175
Boyd, D, Das Sharma, N, Loke, P L, Carroll, J G, Stevenson, P, Hoering, P & Allen, C C R 2021, ' Toluene Dioxygenase-Catalyzed cis-Dihydroxylation of Quinolines: A Molecular Docking Study and Chemoenzymatic Synthesis of Quinoline Arene Oxides ', Frontiers in Bioengineering and Biotechnology . https://doi.org/10.3389/fbioe.2020.619175
Molecular docking studies of quinoline and 2-chloroquinoline substrates at the active site of toluene dioxygenase (TDO), were conducted using Autodock Vina, to identify novel edge-to-face interactions and to rationalize the observed stereoselective c
Autor:
Derek R, Boyd, Narain D, Sharma, Christopher J, McGivern, Paul J, Stevenson, Patrick, Hoering, Christopher C R, Allen
Publikováno v:
The Journal of organic chemistry. 84(23)
Autor:
Christopher J. McGivern, Christopher C. R. Allen, Ian N. Brannigan, Derek R. Boyd, Narain D. Sharma, Colin McRoberts, Peter Nockemann, Patrick Hoering, Paul J. Stevenson
Publikováno v:
Boyd, D, Sharma, N D, Brannigan, I, McGivern, C, Nockemann, P, Stevenson, P, McRoberts, C, Hoering, P & Allen, C C R 2019, ' cis-Dihydroxylation of Tricyclic Arenes and Heteroarenes Catalyzed by Toluene Dioxygenase: A Molecular Docking Study and Experimental Validation ', Advanced Synthesis & Catalysis . https://doi.org/10.1002/adsc.201900147
Molecular docking studies of toluene dioxygenase (TDO) led to the prediction that angular and lateral cis‐dihydroxylation of tricyclic arene and heteroarene substrates could occur. Biotransformations of biphenylene, dibenzofuran, carbazole and dibe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb12ef426b292992c8055c73cf641007
https://pure.qub.ac.uk/en/publications/cisdihydroxylation-of-tricyclic-arenes-and-heteroarenes-catalyzed-by-toluene-dioxygenase-a-molecular-docking-study-and-experimental-validation(50853b4a-7862-402a-80bc-d5045176e60a).html
https://pure.qub.ac.uk/en/publications/cisdihydroxylation-of-tricyclic-arenes-and-heteroarenes-catalyzed-by-toluene-dioxygenase-a-molecular-docking-study-and-experimental-validation(50853b4a-7862-402a-80bc-d5045176e60a).html
Autor:
John F. Malone, Steven D. Shepherd, Derek R. Boyd, Christopher C. R. Allen, Deirdre Murphy, Vera Ljubez, Narain D. Sharma
Publikováno v:
Organic & Biomolecular Chemistry. 14:2651-2664
Enantiopure β-hydroxy sulfoxides and catechol sulfoxides were obtained, by chemoenzymatic synthesis, involving dioxygenase-catalysed benzylic hydroxylation or arene cis-dihydroxylation and cis-diol dehydrogenase-catalysed dehydrogenation. Absolute c
Autor:
Timofey, Skvortsov, Patrick, Hoering, Ksenia, Arkhipova, Roger C, Whitehead, Derek R, Boyd, Christopher C R, Allen
Publikováno v:
Genome Announcements
Here, we present draft genome sequences of Pseudomonas putida strains UV4 and UV4/95, which demonstrate an ability to conduct a wide range of industrially important biotransformations of arenes, alkenes, and phenols.
Autor:
Christopher C. R. Allen, Patrick Hoering, Roger C. Whitehead, Timofey Skvortsov, Derek R. Boyd, Ksenia Arkhipova
Publikováno v:
Skvortsov, T, Hoering, P, Arkhipova, K, Whitehead, R C, Boyd, D R & Allen, C C R 2018, ' Draft genome sequences of Pseudomonas putida UV4 and UV4/95, toluene dioxygenaseexpressing producers of cis-1,2-dihydrodiols ', Genome Announcements, vol. 6, no. 1, e01419-17, pp. 1-2 . https://doi.org/10.1128/genomeA.01419-17
Skvortsov, T, Hoering, P, Arkhipova, K, Whitehead, R, Boyd, D R & Allen, C C R 2018, ' Draft Genome Sequences of Pseudomonas putida UV4 and UV4/95, Toluene Dioxygenase-Expressing Producers of cis-1,2-Dihydrodiols ', Genome Announcements, vol. 4, no. 1, e01419-17 . https://doi.org/10.1128/genomeA.01419-17
Skvortsov, T, Hoering, P, Arkhipova, K, Whitehead, R, Boyd, D R & Allen, C C R 2018, ' Draft Genome Sequences of Pseudomonas putida UV4 and UV4/95, Toluene Dioxygenase-Expressing Producers of cis-1,2-Dihydrodiols ', Genome Announcements, vol. 4, no. 1, e01419-17 . https://doi.org/10.1128/genomeA.01419-17
Here, we present draft genome sequences of Pseudomonas putida strains UV4 and UV4/95, which demonstrate an ability to conduct a wide range of industrially important biotransformations of arenes, alkenes, and phenols.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5e762ab771dfaa7673462a972134e9
https://pure.qub.ac.uk/en/publications/draft-genome-sequences-of-pseudomonas-putida-uv4-and-uv495-toluene-dioxygenaseexpressing-producers-of-cis12dihydrodiols(934c289e-874e-46a1-92ee-927302a71b73).html
https://pure.qub.ac.uk/en/publications/draft-genome-sequences-of-pseudomonas-putida-uv4-and-uv495-toluene-dioxygenaseexpressing-producers-of-cis12dihydrodiols(934c289e-874e-46a1-92ee-927302a71b73).html