Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Derek Norris"'
Autor:
Matthew D. Hill, Haiquan Fang, Derek Norris, George V. Delucca, Hong Huang, Mikkel DeBenedetto, Claude Quesnelle, William D. Schmitz, John S. Tokarski, Steven Sheriff, Chunhong Yan, Caroline Fanslau, Zuzana Haarhoff, Christine Huang, Melissa Kramer, Shilpa Madari, Krista Menard, Laura Monereau, John Morrison, Nirmala Raghavan, Eric E. Shields, Jean Simmermacher-Mayer, Michael Sinz, Ching Kim Tye, Richard Westhouse, Chunshan Xie, Haiying Zhang, Lisa Zhang, Tatyana Zvyaga, Francis Lee, Ashvinikumar V. Gavai, Andrew P. Degnan
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1165-1171
We describe the synthesis of triazole-containing carboline derivatives and their utility as bromodomain and extra-terminal (BET) inhibitors. A convergent synthetic route permitted the detailed investigation of deuteration and fluorination strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e35ad654e0ca7192653d0e07258cff5
https://doi.org/10.1021/acsmedchemlett.2c00219
https://doi.org/10.1021/acsmedchemlett.2c00219
Autor:
Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
Supplementary Tables 1-3, Figure Legends 1-6 from Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f909ef46a03d1570a27d99c5261e2b
https://doi.org/10.1158/1078-0432.22441917.v1
https://doi.org/10.1158/1078-0432.22441917.v1
Autor:
Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
Purpose: The extensive involvement of the HER kinases in epithelial cancer suggests that kinase inhibitors targeting this receptor family have the potential for broad spectrum antitumor activity. BMS-690514 potently inhibits all three HER kinases, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f1ae66761ffc51c82294bcb244134
https://doi.org/10.1158/1078-0432.c.6518787
https://doi.org/10.1158/1078-0432.c.6518787
Autor:
Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong
Supplementary Figures 1-6 from Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10077e61e239f1a813c40834f158a23d
https://doi.org/10.1158/1078-0432.22441920
https://doi.org/10.1158/1078-0432.22441920
Autor:
Ping, Chen, Arthur M, Doweyko, Derek, Norris, Henry H, Gu, Steven H, Spergel, Jagabundhu, Das, Robert V, Moquin, James, Lin, John, Wityak, Edwin J, Iwanowicz, Kim W, McIntyre, David J, Shuster, Kamelia, Behnia, Saeho, Chong, Henry, de Fex, Suhong, Pang, Sydney, Pitt, Ding Ren, Shen, Sara, Thrall, Paul, Stanley, Octavian R, Kocy, Mark R, Witmer, Steven B, Kanner, Gary L, Schieven, Joel C, Barrish
Publikováno v:
Journal of medicinal chemistry. 47(18)
A series of novel anilino 5-azaimidazoquinoxaline analogues possessing potent in vitro activity against p56Lck and T cell proliferation have been discovered. Subsequent SAR studies led to the identification of compound 4 (BMS-279700) as an orally act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eeefc933c38e91d86c7a4419e6c5d487
https://pubmed.ncbi.nlm.nih.gov/15317463
https://pubmed.ncbi.nlm.nih.gov/15317463
Autor:
Scott H, Watterson, Marianne, Carlsen, T G Murali, Dhar, Zhongqi, Shen, William J, Pitts, Junqing, Guo, Henry H, Gu, Derek, Norris, John, Chorba, Ping, Chen, Daniel, Cheney, Mark, Witmer, Catherine A, Fleener, Katherine, Rouleau, Robert, Townsend, Diane L, Hollenbaugh, Edwin J, Iwanowicz
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(3)
A series of novel quinolone-based small molecule inhibitors of inosine monophosphate dehydrogenase (IMPDH) was explored. The synthesis and the structure-activity relationships (SARs) derived from in vitro studies are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c8955482e9f2429abef464a1ed08d76
https://pubmed.ncbi.nlm.nih.gov/12565968
https://pubmed.ncbi.nlm.nih.gov/12565968
Autor:
Derek Norris
Publikováno v:
Nursing Older People. 10:36-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ba7b7984d0d2ea5e2627a5f15e0864
https://doi.org/10.7748/nop.10.6.36.s26
https://doi.org/10.7748/nop.10.6.36.s26