Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Derek Ng"'
Autor:
Swetha Anandhan, Shelley Herbrich, Sangeeta Goswami, Baoxiang Guan, Yulong Chen, Marc Daniel Macaluso, Sonali Jindal, Seanu Meena Natarajan, Samuel W. Andrewes, Liangwen Xiong, Ashwat Nagarajan, Sreyashi Basu, Derek Ng Tang, Jielin Liu, Jimin Min, Anirban Maitra, Padmanee Sharma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Resistance to immune checkpoint therapy (ICT) presents a growing clinical challenge. The tumor microenvironment (TME) and its components, namely tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs), play a pivotal rol
Externí odkaz:
https://doaj.org/article/808a92140dc84fc1afc83e30db24608a
Autor:
Anthony N. Muiru, Michael G. Shlipak, Rebecca Scherzer, William R. Zhang, Simon B. Ascher, Vasantha Jotwani, Carl Grunfeld, Chirag R. Parikh, Derek Ng, Frank J. Palella, Ken Ho, Seble Kassaye, Anjali Sharma, Mardge Cohen, Ruibin Wang, Qibin Qi, Michelle M. Estrella
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background HIV-positive persons bear an excess burden of chronic kidney disease (CKD); however, conventional methods to assess kidney health are insensitive and non-specific for detecting early kidney injury. Urinary biomarkers can detect ea
Externí odkaz:
https://doaj.org/article/811826ef6e5045808dd6c851db1262af
Autor:
Robert P Woroniecki, Derek Ng, Sophie Limou, Cheryl A Winkler, Kimberly Jean Reidy, Mark Mitsnefes, Matthew G Sampson, Craig S Wong, Bradley A Warady, Susan L Furth, Jeffrey B Kopp, Frederick Jeffrey Kaskel
Publikováno v:
Frontiers in Pediatrics, Vol 4 (2016)
Background and objectives: African American (AA) children with focal segmental glomerulosclerosis (FSGS) have later onset disease that progresses more rapidly than in non-AA children. It is unclear how APOL1 genotypes contribute to kidney disease ris
Externí odkaz:
https://doaj.org/article/0d7d039bddf3454ba81c74e82edbdd5b
Autor:
Anandhan, Swetha, Herbrich, Shelley, Goswami, Sangeeta, Guan, Baoxiang, Chen, Yulong, Macaluso, Marc Daniel, Jindal, Sonali, Natarajan, Seanu Meena, Andrewes, Samuel W., Xiong, Liangwen, Nagarajan, Ashwat, Basu, Sreyashi, Tang, Derek Ng, Liu, Jielin, Min, Jimin, Maitra, Anirban, Sharma, Padmanee
Publikováno v:
Nature Communications; 7/10/2024, Vol. 15 Issue 1, p1-13, 13p
Autor:
Monica L, Guzman-Limon, Shuai, Jiang, Derek, Ng, Joseph T, Flynn, Bradley, Warady, Susan L, Furth, Joshua A, Samuels
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(10)
BACKGROUND: Nocturnal hypertension is a risk factor for chronic kidney disease (CKD) progression among adults. In children, effects of nocturnal hypertension on CKD progression is less studied. METHODS: We investigated the relationships between noctu
Autor:
Padmanee Sharma, Jianjun Gao, Renata Collazo, James P. Allison, Jorge Blando, Luis Vence, Xuejun Zhang, Derek Ng Tang, Jan Zhang, Liangwen Xiong, Jianfeng Chen, Baoxiang Guan, Tihui Fu, Sangeeta Goswami, Lewis Zhichang Shi
Supplementary Figure and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8191bb86347bd2369890eb2cadced527
https://doi.org/10.1158/2326-6066.22542477
https://doi.org/10.1158/2326-6066.22542477
Autor:
Padmanee Sharma, Jianjun Gao, Renata Collazo, James P. Allison, Jorge Blando, Luis Vence, Xuejun Zhang, Derek Ng Tang, Jan Zhang, Liangwen Xiong, Jianfeng Chen, Baoxiang Guan, Tihui Fu, Sangeeta Goswami, Lewis Zhichang Shi
Adoptive transfer of tumor-reactive T cells (ACT) has led to modest clinical benefit in the treatment of solid tumors. Failures with this therapy are primarily due to inadequate infiltration and poor function of adoptively transferred cells in the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e51e937a450781ba25c31d5304d409
https://doi.org/10.1158/2326-6066.c.6549942
https://doi.org/10.1158/2326-6066.c.6549942
Autor:
Padmanee Sharma, Jingjing Sun, Qiuming He, Derek Ng Tang, Jianjun Gao, Sijin Wen, Dimitra Tsavachidou, Woong-Kyung Suh, Tihui Fu, Hong Chen
The transcription factor T-bet controls the Th1 genetic program in T cells for effective antitumor responses. Anti-CTLA-4 immunotherapy elicits dramatic antitumor responses in mice and in human patients; however, factors that regulate T-bet expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf48999b1556c0ebfb37d69086c92b1
https://doi.org/10.1158/2326-6066.c.6548116.v1
https://doi.org/10.1158/2326-6066.c.6548116.v1
Autor:
Thomas W. Kensler, John D Groopman, Paul Talalay, Jed W. Fahey, Qingzhi Zhang, Nigel P. Botting, Tao Yang Chen, Yuan Rong Zhu, Geng Sun Qian, Derek Ng, Alvaro Muñoz, Lisa P. Jacobson, Marlin D. Friesen, Yong Sheng Chen, Yong Hui Zhang, Jian Zhu, Jian Hua Lu, Yan Sun, Yan Wu, Jin Bing Wang, Jian Guo Chen, Patricia A. Egner
One of several challenges in design of clinical chemoprevention trials is the selection of the dose, formulation, and dose schedule of the intervention agent. Therefore, a cross-over clinical trial was undertaken to compare the bioavailability and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9d7a71e07554f587ba29909c244968
https://doi.org/10.1158/1940-6207.c.6544866
https://doi.org/10.1158/1940-6207.c.6544866
Autor:
Padmanee Sharma, Jingjing Sun, Qiuming He, Derek Ng Tang, Jianjun Gao, Sijin Wen, Dimitra Tsavachidou, Woong-Kyung Suh, Tihui Fu, Hong Chen
PDF file - 441K, Supplementary Figure 1. (A) Schema for clinical trial whereby patients received treatment with anti-CTLA-4. (B) Unsupervised hierarchical clustering of RPPA data obtained from 7 matched pre- and post-therapy samples. (C) Representati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b6da31073ca74f28349945b4ff933a
https://doi.org/10.1158/2326-6066.22536322.v1
https://doi.org/10.1158/2326-6066.22536322.v1