Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Derek N J, Hart"'
Autor:
Ziduo Li, Xinsheng Ju, Pablo A. Silveira, Edward Abadir, Wei-Hsun Hsu, Derek N. J. Hart, Georgina J. Clark
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendr
Externí odkaz:
https://doaj.org/article/a8945944610844f69bdeb5a57c132e10
Autor:
Tsun-Ho Lo, Edward Abadir, Robin E Gasiorowski, Karieshma Kabani, Murari Ramesh, Daniel Orellana, Phillip D Fromm, Fiona Kupresanin, Elizabeth Newman, Ilona Cunningham, Derek N J Hart, Pablo A Silveira, Georgina J Clark
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216368 (2019)
Acute myeloid leukemia (AML) is the most common form of adult acute leukemia with ~20,000 new cases yearly. The disease develops in people of all ages, but is more prominent in the elderly, who due to limited treatment options, have poor overall surv
Externí odkaz:
https://doaj.org/article/75649774d1c04dbaafc3e41c4a7c1ba6
Autor:
Andrew J, Kassianos, Melinda Y, Hardy, Xinsheng, Ju, Dipti, Vijayan, Yitian, Ding, Annelie J E, Vulink, Kylie J, McDonald, Sarah L, Jongbloed, Robert B, Wadley, Christine, Wells, Derek N J, Hart, Kristen J, Radford
Publikováno v:
European journal of immunology. 42(6)
Human blood myeloid DCs can be subdivided into CD1c (BDCA-1)(+) and CD141 (BDCA-3)(+) subsets that display unique gene expression profiles, suggesting specialized functions. CD1c(+) DCs express TLR4 while CD141(+) DCs do not, thus predicting that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa4929ad8c1adcda7753bb6432282559
https://pubmed.ncbi.nlm.nih.gov/22678905
https://pubmed.ncbi.nlm.nih.gov/22678905
Autor:
Melinda M, Dean, Robert L, Flower, Damon P, Eisen, Robyn M, Minchinton, Derek N J, Hart, Slavica, Vuckovic
Publikováno v:
Immunology. 132(2)
Mannose-binding lectin (MBL) is a serum lectin that plays a significant role in innate host defence. Individuals with mutations in exon 1 of the MBL2 gene have reduced MBL ligand binding and complement activation function and increased incidence of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec97ba2dbb17dd84c8d2eb4232300d79
https://pubmed.ncbi.nlm.nih.gov/21091907
https://pubmed.ncbi.nlm.nih.gov/21091907
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 595
Dendritic cells (DC) are critical to the induction and regulation of the innate and adaptive immune responses. They have been implicated in the pathogenesis of many autoimmune and chronic inflammatory diseases as well as contributing to the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d6e7b16d3b543f93795d8cc9b905569
https://pubmed.ncbi.nlm.nih.gov/19941102
https://pubmed.ncbi.nlm.nih.gov/19941102
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 595
Human blood dendritic cells (DCs) are a rare, heterogeneous cell population that comprise approximately 1% of circulating peripheral blood mononuclear cells (PBMCs). Their isolation has been confounded by their scarcity and lack of distinguishing mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d619a7af8c58e371795fc75f2029396a
https://pubmed.ncbi.nlm.nih.gov/19941104
https://pubmed.ncbi.nlm.nih.gov/19941104
Publikováno v:
Advances in cancer research. 99
Since their discovery, there has been significant progress in the understanding of dendritic cell (DC) biology. Their capacity for priming an immune response against pathogens and cancers has been exploited clinically. However, the objective response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::660542e83c615d39b8dde8fe0115f79a
https://pubmed.ncbi.nlm.nih.gov/18037410
https://pubmed.ncbi.nlm.nih.gov/18037410
Autor:
Benjamine J, Cooper, Brian, Key, Adrian, Carter, Nicola Z, Angel, Derek N J, Hart, Masato, Kato
Publikováno v:
The Journal of biological chemistry. 281(32)
Adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) is a novel intracellular protein with approximately 50% protein identity to adenosylhomocysteine hydrolase (AHCY), an important enzyme for metabolizing S-adenosyl-l-homocysteine, the by-product o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4461b8da8a0f4ed0a248471be708bda3
https://pubmed.ncbi.nlm.nih.gov/16754674
https://pubmed.ncbi.nlm.nih.gov/16754674
Publikováno v:
Transplantation. 75(10)
Activated dendritic cells (DC) initiate immune responses by presenting antigen, including alloantigen from tissue grafts, to T lymphocytes. The potential to deplete or inactivate differentiated-activated DC during allogeneic transplantation represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f981f832d7251a86b560b18d0d984ece
https://pubmed.ncbi.nlm.nih.gov/12777863
https://pubmed.ncbi.nlm.nih.gov/12777863
Publikováno v:
Blood. 100(8)
Dendritic cells (DCs) initiate and direct immune responses. Recent studies have defined different DC populations, therefore we undertook this study comparing 2 types of myeloid DCs: blood CD11c(+) DCs and in vitro monocyte-derived DCs (Mo-DCs), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c382cfb3d97016731b8783b1154bebf
https://pubmed.ncbi.nlm.nih.gov/12351396
https://pubmed.ncbi.nlm.nih.gov/12351396