Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Derek MacFadden"'
Autor:
Adhora Mir, Derek Lanoue, Veronica Zanichelli, Carl van Walraven, Timothy Olynych, Caroline Nott, Derek MacFadden
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-7 (2024)
Abstract Background Self-reported penicillin allergy labels are common and often inaccurate after assessment. These labels can lead to reduced use of first-line beta-lactam antibiotics and worse outcomes. We measured the impact of a previously perfor
Externí odkaz:
https://doaj.org/article/1bcc079426db4fbeacbabffa6b4def49
Autor:
Alex M Cressman, Bijun Wen, Sudipta Saha, Hae Young Jun, Riley Waters, Sharan Lail, Aneela Jabeen, Radha Koppula, Lauren Lapointe-Shaw, Kathleen A Sheehan, Adina Weinerman, Nick Daneman, Amol A Verma, Fahad Razak, Derek MacFadden
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0299473 (2024)
ObjectiveCurrent scores for predicting sepsis outcomes are limited by generalizability, complexity, and electronic medical record (EMR) integration. Here, we validate a simple EMR-based score for sepsis outcomes in a large multi-centre cohort.DesignA
Externí odkaz:
https://doaj.org/article/0cd88caec3b44047a5cee6969064cabe
Autor:
Matt Driedger, Nick Daneman, Kevin Brown, Wayne L. Gold, Sarah C.J. Jorgensen, Colleen Maxwell, Kevin L. Schwartz, Andrew M. Morris, Deva Thiruchelvam, Bradley Langford, Elizabeth Leung, Derek MacFadden
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The COVID-19 pandemic has likely influenced the epidemiology of bacterial infections through wide-ranging changes to clinical practices and infection control and prevention interventions. We sought to determine how the detection and incidenc
Externí odkaz:
https://doaj.org/article/5dd6ca0e7bd042199282e47d8b4c7f19
SARS-CoV-2 detection from the built environment and wastewater and its use for hospital surveillance
Autor:
Aaron Hinz, Lydia Xing, Evgueni Doukhanine, Laura A. Hug, Rees Kassen, Banu Ormeci, Richard J. Kibbee, Alex Wong, Derek MacFadden, Caroline Nott
Publikováno v:
FACETS, Vol 7, Iss , Pp 82-97 (2022)
Patients hospitalized with SARS-CoV-2 infections are major contributors to morbidity and mortality in health care settings. Our understanding of the distribution of this virus in the built health care environment and wastewater, and relationship to d
Externí odkaz:
https://doaj.org/article/e71d56ea784649fc892aca09e24e6493
Autor:
Andrea Benedetti, Cecilia T Costiniuk, Kosar Khwaja, Andrew Johnson, Barret Rush, Darrell Tan, Ranjani Somayaji, Salman Qureshi, Michaeline McGuinty, Nicole Ezer, Sara Belga, Emily G. McDonald, Zahra N. Sohani, Guillaume Butler-Laporte, Andrew Aw, Alex Carignan, Matthew P. Cheng, Bryan Coburn, Dan Gregson, Alexander Lawandi, Victor Leung, Sylvain Lother, Derek MacFadden, Leighanne Parkes, Valerie Roy, Ilan Schwartz, Miranda So, Emilie Trinh, Todd C. Lee
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Introduction Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection of immunocompromised hosts with significant morbidity and mortality. The current standard of care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose of 15–20 mg/kg/da
Externí odkaz:
https://doaj.org/article/93d2ad50457b4909a009a29a7dcc8958
Autor:
Kednapa Thavorn, Howsikan Kugathasan, Darrell H. S. Tan, Nasheed Moqueet, Stefan D. Baral, Becky Skidmore, Derek MacFadden, Anna Simkin, Sharmistha Mishra
Publikováno v:
Systematic Reviews, Vol 7, Iss 1, Pp 1-7 (2018)
Abstract Background Pre-exposure prophylaxis (PrEP) with antiretrovirals is an efficacious and effective intervention to decrease the risk of HIV (human immunodeficiency virus) acquisition. Yet drug and delivery costs prohibit access in many jurisdic
Externí odkaz:
https://doaj.org/article/db005f7a9843422fbd464b51087d3044
Autor:
Adhora Mir, Derek Lanoue, Derek Macfadden, Carl van Walraven, Veronica Zanichelli, Caroline Nott
Background. Penicillin allergy labels are common and are often inaccurate. These labels can lead to unnecessary use of second-line non-beta-lactam antibiotics, and worse clinical outcomes. Objectives. We measured the impact of the introducing of a st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb8506487910d4e4611dd2334b93e35
https://doi.org/10.1101/2023.05.29.23290698
https://doi.org/10.1101/2023.05.29.23290698
Autor:
Jean-Paul R Soucy, Bradley J Langford, Miranda So, Sumit Raybardhan, Derek MacFadden, Nick Daneman, Silvia Bertagnolio
Publikováno v:
The Lancet Microbe.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a93ca38fb80810eeba4a9e3cdb3911fa
https://doi.org/10.1016/s2666-5247(23)00098-8
https://doi.org/10.1016/s2666-5247(23)00098-8
Autor:
Daniel, Teitelbaum, Marion, Elligsen, Kevin, Katz, Philip W, Lam, Jennifer, Lo, Derek, MacFadden, Christie, Vermeiren, Nick, Daneman
Publikováno v:
Clinical Infectious Diseases. 75:1763-1771
Background Hospital antibiograms guide initial empiric antibiotic treatment selections, but do not directly inform escalation of treatment among nonresponding patients. Methods Using gram-negative bacteremia as an exemplar condition, we sought to int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0332f934f6fdfe6ad32de7163bd42e
https://doi.org/10.1093/cid/ciac256
https://doi.org/10.1093/cid/ciac256
Autor:
Michael Fralick, Jason Moggridge, Lucas Castellani, Sylva Donaldson, David S Guttman, Aaron Hinz, Laura Hug, Doug Manuel, Allison McGeer, Hebah Mejbel, Caroline Nott, Ashley Raudanskis, Nisha Thampi, Alex Wong, Veronica Zanichelli, Rees Kassen, Derek Macfadden
Publikováno v:
Open Forum Infectious Diseases. 9
Background Environmental surveillance of SARS-CoV-2 via wastewater has become an invaluable tool for population-level surveillance of COVID-19. More highly resolved environmental sampling approaches may also be useful for surveillance. Built environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f4aa3b9d402337a14e6e48cbf5d9fd
https://doi.org/10.1093/ofid/ofac492.1506
https://doi.org/10.1093/ofid/ofac492.1506