Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Derek M. Mason"'
Autor:
Florian Bieberich, Rodrigo Vazquez-Lombardi, Alexander Yermanos, Roy A. Ehling, Derek M. Mason, Bastian Wagner, Edo Kapetanovic, Raphael Brisset Di Roberto, Cédric R. Weber, Miodrag Savic, Fabian Rudolf, Sai T. Reddy
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
COVID-19 disease outcome is highly dependent on adaptive immunity from T and B lymphocytes, which play a critical role in the control, clearance and long-term protection against SARS-CoV-2. To date, there is limited knowledge on the composition of th
Externí odkaz:
https://doaj.org/article/58093dc6db8142b5b3de4dd735ee05d1
Autor:
Lea Azour, Yunan Hu, Jane P. Ko, Baiyu Chen, Florian Knoll, Jeffrey B. Alpert, Geraldine Brusca-Augello, Derek M. Mason, Maj L. Wickstrom, Young Joon (Fred) Kwon, James Babb, Zhengrong Liang, William H. Moore
Publikováno v:
Journal of Computer Assisted Tomography. 47:212-219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c59809828ceeb80974d98dff1b7ad6f
https://doi.org/10.1097/rct.0000000000001405
https://doi.org/10.1097/rct.0000000000001405
Autor:
Jan Dahinden, Simon M Meng, Christian Jordi, Derek M Mason, Lucia Bonati, Bruno E. Correia, Roy A. Ehling, Pablo Gainza, Simon Friedensohn, Bastian Wagner, Sai T. Reddy, Cédric R. Weber
Publikováno v:
Nature Biomedical Engineering. 5:600-612
The optimization of therapeutic antibodies is time-intensive and resource-demanding, largely because of the low-throughput screening of full-length antibodies (approximately 1 x 10(3) variants) expressed in mammalian cells, which typically results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d437cc590277fc33814dfff7cea9cf
https://doi.org/10.1038/s41551-021-00699-9
https://doi.org/10.1038/s41551-021-00699-9
Autor:
Roy A. Ehling, Cédric R. Weber, Derek M. Mason, Simon Friedensohn, Bastian Wagner, Florian Bieberich, Edo Kapetanovic, Rodrigo Vazquez-Lombardi, Raphaël B. Di Roberto, Kai-Lin Hong, Camille Wagner, Michele Pataia, Max D. Overath, Daniel J. Sheward, Ben Murrell, Alexander Yermanos, Andreas P. Cuny, Miodrag Savic, Fabian Rudolf, Sai T. Reddy
Publikováno v:
Cell Reports
Cell Reports, 38 (3)
Cell Reports, 38 (3)
Characterization of COVID-19 antibodies has largely focused on memory B cells; however, it is the antibody-secreting plasma cells that are directly responsible for the production of serum antibodies, which play a critical role in resolving SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9780eee78187f0a54828d4403ac33a2e
https://pubmed.ncbi.nlm.nih.gov/34998467
https://pubmed.ncbi.nlm.nih.gov/34998467
Autor:
Alexander Yermanos, Andreas P. Cuny, Raphael Brisset Di Roberto, Fabian Rudolf, Kai-Lin Hong, Camille Wagner, Derek M Mason, Edo Kapetanovic, Miodrag Savic, Bastian Wagner, Florian Bieberich, Sai T. Reddy, Cédric R. Weber, Rodrigo Vazquez-Lombardi, Daniel J. Sheward, Ben Murrell, Simon Friedensohn, Roy A. Ehling
Isolation and characterization of antibodies in COVID-19 patients has largely focused on memory B cells, however it is the antibody-secreting plasma cells that are directly responsible for the production of serum antibodies, which play a critical rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981d66373380d3f4576b9e587ad3acf6
https://doi.org/10.1101/2021.02.12.430940
https://doi.org/10.1101/2021.02.12.430940
Autor:
Raphael Brisset Di Roberto, Alexander Yermanos, Sai T. Reddy, Derek M Mason, Rodrigo Vazquez-Lombardi, Bastian Wagner, Cédric R. Weber, Roy A. Ehling, Edo Kapetanovic, Florian Bieberich, Miodrag Savic, Fabian Rudolf
COVID-19 disease outcome is highly dependent on adaptive immunity from T and B lymphocytes, which play a critical role in the control, clearance and long-term protection against SARS-CoV-2. To date, there is limited knowledge on the composition of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056c702ea2ff4393e1415e1c180e2382
https://doi.org/10.1101/2021.02.12.430907
https://doi.org/10.1101/2021.02.12.430907
Autor:
Sai T. Reddy, Lucia Csepregi, Tarik A. Khan, Lena Erlach, Cristina Parola, Arthur R. Gorter de Vries, Derek M Mason, Simon Friedensohn, Daniel Neumeier
SUMMARYAdaptive immunity is driven by the ability of lymphocytes to undergo V(D)J recombination and generate a highly diverse set of immune receptors (B cell receptors/secreted antibodies and T cell receptors) and their subsequent clonal selection an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322e7d43bd00b3801cbc83a6042f98f9
Autor:
Christina Krebs, Bastian Wagner, Derek M Mason, Nadine Periat, J. Linnik, Thomas Goetz, Thomas Hochueli, Therese Ruf, Karin Stoll-Rudin, Tanja Renz, Christoph Niederhauser, Miodrag Savic, Lukas Mundorff, Beatrice Nickel, Daniel H. Paris, Julia Deichmann, Hans-Michael Kaltenbach, Sergio Haymoz, Fabian Rudolf, Michele Richert, Carlos Quinto, Sai T. Reddy, Edo Kapetanovic, Raffaele Altamura, Sergio B Sesia, Nicole Probst-Hensch, Markus Hosch
Background To accurately measure seroprevalance in the population, both the expected immune response as well as the assay performances have to be well characterised. Here, we describe the collection and initial characterisation of a blood and saliva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2049efbf173753598b0a4aa2a62f1d83
Autor:
Derek M Mason, Simon Friedensohn, Cédric R Weber, Christian Jordi, Bastian Wagner, Simon Meng, Pablo Gainza, Bruno E Correia, Sai T Reddy
Therapeutic antibody optimization is time and resource intensive, largely because it requires low-throughput screening (103 variants) of full-length IgG in mammalian cells, typically resulting in only a few optimized leads. Here, we use deep learning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4372a7323ce15d18febc0d0004dbf0f0
https://doi.org/10.1101/617860
https://doi.org/10.1101/617860
Autor:
Sai T. Reddy, Lucia Csepregi, Cristina Parola, Daniel Neumeier, Derek M Mason, Simon Friedensohn, Mariangela Di Tacchio
Publikováno v:
mAbs, 11 (8)
mAbs
mAbs
Antibody engineering in mammalian cells offers the important advantage of expression and screening of libraries in their native conformation, increasing the likelihood of generating candidates with more favorable molecular properties. Major advances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5434e7b60f5be8e327f84ce19d9c2d5
https://hdl.handle.net/20.500.11850/367967
https://hdl.handle.net/20.500.11850/367967