Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Derek M McKay"'
Autor:
Sruthi Rajeev, ShuHua Li, Aralia Leon-Coria, Arthur Wang, Lucas Kraemer, Susan Joanne Wang, Annaliese Boim, Kyle Flannigan, Adam Shute, Cristiane H Baggio, Blanca E Callejas, Wallace K MacNaughton, Constance A M Finney, Derek M McKay
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012381 (2024)
Recognizing that enteric tuft cells can signal the presence of nematode parasites, we investigated whether tuft cells are required for the expulsion of the cestode, Hymenolepis diminuta, from the non-permissive mouse host, and in concomitant anti-hel
Externí odkaz:
https://doaj.org/article/4b9f7af5d33445d9957cca21ab26e215
Autor:
Subrata Ghosh, Levinus A Dieleman, Christopher Ma, Ian Lewis, Herman W Barkema, Humberto Jijon, Kathy D McCoy, Georgios V Gkoutos, Maitreyi Raman, Lorian M Taylor, Jeff K Vallance, Derek M McKay, David M Mutch, Deanna Gibson, Marcus Rauch
Publikováno v:
BMJ Open Gastroenterology, Vol 9, Iss 1 (2022)
Introduction Dietary patterns that might induce remission in patients with active Crohn’s disease (CD) are of interest to patients, but studies are limited in the published literature. We aim to explore the efficacy of the CD therapeutic dietary in
Externí odkaz:
https://doaj.org/article/519cdb9c6d2948169c34acac6b097c7d
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005390 (2017)
BACKGROUND:In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is
Externí odkaz:
https://doaj.org/article/b89803ca03ad4b9dab897fd18e31c546
Autor:
José L Reyes, Maria R Fernando, Fernando Lopes, Gabriella Leung, Nicole L Mancini, Chelsea E Matisz, Arthur Wang, Derek M McKay
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005481 (2016)
Interleukin (IL)-22, an immune cell-derived cytokine whose receptor expression is restricted to non-immune cells (e.g. epithelial cells), can be anti-inflammatory and pro-inflammatory. Mice infected with the tapeworm Hymenolepis diminuta are protecte
Externí odkaz:
https://doaj.org/article/377689ea972543d092e42eda5c7abf8c
Autor:
Derek M McKay
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 100, Pp 205-210 (2005)
Many studies demonstrate that intestinal inflammation is either initiated or exaggerated by a component of the normal microbiota, most likely commensal bacteria or products derived from these organisms. We review the nature of human inflammatory bowe
Externí odkaz:
https://doaj.org/article/e3cc4aae28484df8be5a00789a38b340
Autor:
Derek M McKay
Publikováno v:
Canadian Journal of Gastroenterology, Vol 18, Iss 5, Pp 347-351 (2004)
The goal of the Research Committee is to build, in collaboration with the Canadian Institutes of Health Research (CIHR) and the Canadian Association of Gastroenterology (CAG) partners, Canadian capacity and expertise in the discipline of gastroentero
Externí odkaz:
https://doaj.org/article/bf8df946bfb84f3a938846f205608fe8
Autor:
Derek M McKay
Publikováno v:
Canadian Journal of Gastroenterology, Vol 16, Iss 8, Pp 565-568 (2002)
Externí odkaz:
https://doaj.org/article/2738761ac321447ca9e72db90c25f76a
Autor:
Derek M McKay
Publikováno v:
Canadian Journal of Gastroenterology, Vol 13, Iss 6, Pp 509-516 (1999)
The idea that the enteric microflora play a role in the pathogenesis or pathophysiology of inflammatory bowel disease (IBD) is not new. Indeed, identification of an infective cause for chronic IBD, and particularly for Crohn’s disease, has been the
Externí odkaz:
https://doaj.org/article/e3e52d4dadd4405496e5307c0e8d3f56
Autor:
Derek M McKay, Sandra Daniels
Publikováno v:
Canadian Journal of Gastroenterology, Vol 17, Iss 7, Pp 437-439 (2003)
The Canadian Association of Gastroenterology (CAG) postdoctoral fellowship programme was initiated in 1992 with the goal of promoting excellence in Canadian gastroenterological research. With backing from multiple pharmaceutical partners and the Cana
Externí odkaz:
https://doaj.org/article/ef48533410474cd49699c495312ba8c8
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38441 (2012)
Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions. Here we investigated the potential fo
Externí odkaz:
https://doaj.org/article/c12bb0c1c9e44de39dddf746aa544bb7