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pro vyhledávání: '"Derek Leroith"'
Autor:
Amanda Leiter, Christian Stephens, Grace Mhango, Chung Yin Kong, Keith Sigel, Jenny J. Lin, Emily J. Gallagher, Derek LeRoith, Juan P. Wisnivesky
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17969- (2023)
Background: Diabetes is a common comorbidity in patients with early-stage non-small cell lung cancer (NSCLC), a growing population due to increased LC screening. However, it is unknown if diabetes is associated with less aggressive NSCLC treatment an
Externí odkaz:
https://doaj.org/article/a8096ff8ffb942129483f1474d71756b
Autor:
Syed Faizan Mehdi, Suma Pusapati, Muhammad Saad Anwar, Durga Lohana, Parkash Kumar, Savitri Aninditha Nandula, Fatima Kausar Nawaz, Kevin Tracey, Huan Yang, Derek LeRoith, Michael J. Brownstein, Jesse Roth
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Inflammation contributes to many chronic conditions. It is often associated with circulating pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity. They are often elevated and can serve as markers of inflammation.
Externí odkaz:
https://doaj.org/article/f2ec9652ecfc4841a5a9bbbe468159e4
Akademický článek
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Autor:
Alison E. Obr, Joseph J. Bulatowicz, Yun-Juan Chang, Virginia Ciliento, Alexander Lemenze, Krystopher Maingrette, Quan Shang, Emily J. Gallagher, Derek LeRoith, Teresa L. Wood
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe acquisition of a metastatic phenotype is the critical event that determines patient survival from breast cancer. Several receptor tyrosine kinases have functions both in promoting and inhibiting metastasis in breast tumors. Although t
Externí odkaz:
https://doaj.org/article/7b5e349e437a4cefac665b8cc2f837ff
Autor:
Haim Werner, Derek LeRoith
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The identification of a series of attributes or hallmarks that are shared by virtually all cancer cells constitutes a true milestone in cancer research. The conceptualization of a catalogue of common genetic, molecular, biochemical and cellular event
Externí odkaz:
https://doaj.org/article/79da0c877e514577bed0a3f6a9871644
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Expression of the low-density lipoprotein receptor (LDLR) has been shown to play a critical role in hypercholesterolemia-associated breast cancer growth and is associated with shorter recurrence-free survival in human breast cancer studies.
Externí odkaz:
https://doaj.org/article/4637f21548d947e5b1af8ade15841430
Autor:
Emily J. Gallagher, Kezhen Fei, Sheldon M. Feldman, Elisa Port, Neil B. Friedman, Susan K. Boolbol, Brigid Killelea, Melissa Pilewskie, Lydia Choi, Tari King, Anupma Nayak, Rebeca Franco, Daliz Cruz, Irini M. Antoniou, Derek LeRoith, Nina A. Bickell
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Racial disparities in breast cancer survival between Black and White women persist across all stages of breast cancer. The metabolic syndrome (MetS) of insulin resistance disproportionately affects more Black than White women. It
Externí odkaz:
https://doaj.org/article/dbb802256d2542bdaa3a9fa52e21db53
Oxytocin and Related Peptide Hormones: Candidate Anti-Inflammatory Therapy in Early Stages of Sepsis
Autor:
Syed Faizan Mehdi, Suma Pusapati, Raja Ram Khenhrani, Muhammad Saad Farooqi, Sobia Sarwar, Ahmad Alnasarat, Nimisha Mathur, Christine Noel Metz, Derek LeRoith, Kevin J. Tracey, Huan Yang, Michael J. Brownstein, Jesse Roth
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis is a potentially life-threatening systemic inflammatory syndrome characterized by dysregulated host immunological responses to infection. Uncontrolled immune cell activation and exponential elevation in circulating cytokines can lead to sepsis
Externí odkaz:
https://doaj.org/article/21f5b345afbb49c096c7bb714598fe76
Autor:
Kristina I. Rother
Publikováno v:
New England Journal of Medicine. 359:323-324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ba477d8796867a5324bfbc96015d01
https://doi.org/10.1056/nejmbkrev0804276
https://doi.org/10.1056/nejmbkrev0804276
Publikováno v:
Molecular Metabolism, Vol 52, Iss , Pp 101245- (2021)
Background: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in normal human physiology and disease sta
Externí odkaz:
https://doaj.org/article/091a5bb9a4a24eefb5a1bd8bf5cc2b72