Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Derek Laver"'
Autor:
Ruitao Jin, Sitong He, Katrina A. Black, Oliver B. Clarke, Di Wu, Jani R. Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M. Colman, Carol V. Robinson, Derek Laver, Brian J. Smith, Jacqueline M. Gulbis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The Kir potassium channels are known to operate and gate without a major conformational change. Here, the authors identify the permeation gate of Kir channels as a steric plug within the conduction pathway, describing how tightly associated anionic l
Externí odkaz:
https://doaj.org/article/400ab475f64247199cf3b4d67129ff32
Autor:
Urvashy Gopaul, Derek Laver, Leeanne Carey, Thomas Matyas, Paulette van Vliet, Robin Callister
Publikováno v:
Sensors, Vol 23, Iss 6, p 3291 (2023)
Sensor-based devices can record pressure or force over time during grasping and therefore offer a more comprehensive approach to quantifying grip strength during sustained contractions. The objectives of this study were to investigate the reliability
Externí odkaz:
https://doaj.org/article/c01c14d2337a427db9a1e0e61a3e58af
Autor:
Katrina A. Black, Sitong He, Ruitao Jin, David M. Miller, Jani R. Bolla, Oliver B. Clarke, Paul Johnson, Monique Windley, Christopher J. Burns, Adam P. Hill, Derek Laver, Carol V. Robinson, Brian J. Smith, Jacqueline M. Gulbis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The transition between conducting and non-conducting states of K+ channels has been explained by conformational changes at the intracellular entrance to the conduction pathway. Here authors demonstrate that control over K+ currents in Kir channels is
Externí odkaz:
https://doaj.org/article/1df537b978c34d8f93ba5ec69176a90f
Autor:
Sergiy V. Korol, Zhe Jin, Yang Jin, Amol K. Bhandage, Anders Tengholm, Nikhil R. Gandasi, Sebastian Barg, Daniel Espes, Per-Ola Carlsson, Derek Laver, Bryndis Birnir
Publikováno v:
EBioMedicine, Vol 30, Iss , Pp 273-282 (2018)
In human pancreatic islets, the neurotransmitter γ-aminobutyric acid (GABA) is an extracellular signaling molecule synthesized by and released from the insulin-secreting β cells. The effective, physiological GABA concentration range within human is
Externí odkaz:
https://doaj.org/article/1bc71a74c5a548beb4885579c8991456
Publikováno v:
IEEE Transactions on Biomedical Engineering. 70:1298-1309
The objective of this paper is to develop a computationally efficient simulation model of Calcium signalling in cardiomyocytes. The model considered here consists of more than two million stiff, nonlinear, and stochastic systems, each of which is com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805e3867eb11ce59573a9daaef7e21f8
https://doi.org/10.1109/tbme.2022.3215169
https://doi.org/10.1109/tbme.2022.3215169
Autor:
Sergiy V, Korol, Zhe, Jin, Yang, Jin, Amol K, Bhandage, Anders, Tengholm, Nikhil R, Gandasi, Sebastian, Barg, Daniel, Espes, Per-Ola, Carlsson, Derek, Laver, Bryndis, Birnir
Publikováno v:
EBioMedicine
In human pancreatic islets, the neurotransmitter γ-aminobutyric acid (GABA) is an extracellular signaling molecule synthesized by and released from the insulin-secreting β cells. The effective, physiological GABA concentration range within human is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8e446aa2e063fe4b0127d9772ab9be1
https://pubmed.ncbi.nlm.nih.gov/29606630
https://pubmed.ncbi.nlm.nih.gov/29606630