Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Derek L. Carbaugh"'
Autor:
Douglas G. Widman, Ellen Young, Boyd L. Yount, Kenneth S. Plante, Emily N. Gallichotte, Derek L. Carbaugh, Kayla M. Peck, Jessica Plante, Jesica Swanstrom, Mark T. Heise, Helen M. Lazear, Ralph S. Baric
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Zika virus (ZIKV), a mosquito-borne flavivirus discovered in 1947, has only recently caused large outbreaks and emerged as a significant human pathogen. In 2015, ZIKV was detected in Brazil, and the resulting epidemic has spread throughout t
Externí odkaz:
https://doaj.org/article/badd76acfe644f0ea9b1b6e9afa5d37b
Autor:
Cameron Adams, Derek L Carbaugh, Bo Shu, Thiam-Seng Ng, Izabella N Castillo, Ryan Bhowmik, Bruno Segovia-Chumbez, Ana C Puhl, Stephen Graham, Sean A Diehl, Helen M Lazear, Shee-Mei Lok, Aravinda M de Silva, Lakshmanane Premkumar
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1010814 (2023)
We currently have an incomplete understanding of why only a fraction of human antibodies that bind to flaviviruses block infection of cells. Here we define the footprint of a strongly neutralizing human monoclonal antibody (mAb G9E) with Zika virus (
Externí odkaz:
https://doaj.org/article/470ce3319ca643cab15d968be35cdd93
Autor:
Derek L. Carbaugh, Helen M. Lazear
Publikováno v:
J Virol
Flaviviruses encode one, two, or no N -linked glycosylation sites on their envelope proteins. Glycosylation can impact virus interactions with cell surface attachment factors and also may impact virion stability and virus replication. Envelope protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105384b13b905f7df2cce764ca28cdf
https://doi.org/10.1128/jvi.00104-20
https://doi.org/10.1128/jvi.00104-20
Autor:
Helen M. Lazear, Nathaniel J. Moorman, Derek L. Carbaugh, Ronald Swanstrom, Wes Sanders, Shuntai Zhou
Publikováno v:
J Virol
Recent Zika virus (ZIKV) outbreaks and unexpected clinical manifestations of ZIKV infection have prompted an increase in ZIKV-related research. Here, we identify two strain-specific determinants of ZIKV virulence in mice. We found that strain H/PF/20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee5777c4199d4b705a0da78ea32207c
https://pubmed.ncbi.nlm.nih.gov/32796074
https://pubmed.ncbi.nlm.nih.gov/32796074
Publikováno v:
Journal of Virology. 93
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus. Recent ZIKV outbreaks have produced serious human disease, including neurodevelopmental malformations (congenital Zika syndrome) and Guillain-Barré syndrome. These outcomes were not associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3deb8cbeb79d2c5ad9f47c5bb3fcd455
https://doi.org/10.1128/jvi.00113-19
https://doi.org/10.1128/jvi.00113-19