Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Derek K. Toomre"'
Autor:
Ling Chu, Jonathan Tyson, Juliana E. Shaw, Felix Rivera-Molina, Anthony J. Koleske, Alanna Schepartz, Derek K. Toomre
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
High density environmentally sensitive (HIDE) probes allow for long time-lapse super-resolution imaging of live cells. Here the authors develop a second HIDE probe with a bio-orthogonal labelling strategy to enable two-color nanoscopy of two organell
Externí odkaz:
https://doaj.org/article/91511d84bdfc4dfb9363382cbb779831
Autor:
Myun Hwa Dunlop, Andreas M. Ernst, Lena K. Schroeder, Derek K. Toomre, Grégory Lavieu, James E. Rothman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The different composition of Golgi cisternae gave rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesicles and another one where cisternae biochemically mature to ensure anterograde transport. Here, th
Externí odkaz:
https://doaj.org/article/6f898b5c86a84ecca1c0327ce3e908d0
Autor:
Francesca Bottanelli, Emil B. Kromann, Edward S. Allgeyer, Roman S. Erdmann, Stephanie Wood Baguley, George Sirinakis, Alanna Schepartz, David Baddeley, Derek K. Toomre, James E. Rothman, Joerg Bewersdorf
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-5 (2016)
The intracellular applications of STED microscopy are limited by the availability of dyes. Here the authors develop a two-colour labelling strategy based on SiR and ATTO590 dyes, and apply their strategy to image various subcellular membrane compartm
Externí odkaz:
https://doaj.org/article/ea973638e80347418c454d3d0a47cc6b
Autor:
Rushika M. Perera, Roberto Zoncu, Terrance G. Johns, Marc Pypaert, Fook-Thean Lee, Ira Mellman, Lloyd J. Old, Derek K. Toomre, Andrew M. Scott
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 12, Pp 1099-1110 (2007)
Overexpression of the epidermal growth factor receptor (EGFR) in epithelial tumors is associated with poor prognosis and is the target for a number of cancer therapeutics. Monoclonal antibody (mAb) 806 is a novel anti-EGFR antibody with significant t
Externí odkaz:
https://doaj.org/article/7037df0cbea3460c9d4810c8ff9b2c64
Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion
Publikováno v:
Journal of Cell Biology. 222
Fibronectin (FN) is an essential structural and regulatory component of the extracellular matrix (ECM), and its binding to integrin receptors supports cell adhesion, migration, and signaling. Here, using live-cell microscopy of fibroblasts expressing
Autor:
Eugene Tkachenko, Dan Tse, Olga Sideleva, Sophie J Deharvengt, Marcus R Luciano, Yan Xu, Caitlin L McGarry, John Chidlow, Paul F Pilch, William C Sessa, Derek K Toomre, Radu V Stan
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32655 (2012)
PV1 protein is an essential component of stomatal and fenestral diaphragms, which are formed at the plasma membrane of endothelial cells (ECs), on structures such as caveolae, fenestrae and transendothelial channels. Knockout of PV1 in mice results i
Externí odkaz:
https://doaj.org/article/69c4454d534d49dd93a397fab9fce813