Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Derek J.R. Ransburgh"'
Autor:
Jeffrey D. Parvin, Kun Huang, Charles L. Shapiro, Robert T. Pilarski, Gang He, Derek J.R. Ransburgh, Alicia Zha, Haritha Mathsyaraja, Sanford H. Barsky, Zeina Kais
To find genes and proteins that collaborate with BRCA1 or BRCA2 in the pathogenesis of breast cancer, we used an informatics approach and found a candidate BRCA interactor, KIAA0101, to function like BRCA1 in exerting a powerful control over centroso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a568c8afe723d12f0f9ec1960b6ee89
https://doi.org/10.1158/1541-7786.c.6542176
https://doi.org/10.1158/1541-7786.c.6542176
Autor:
Jeffrey D. Parvin, Kun Huang, Charles L. Shapiro, Robert T. Pilarski, Gang He, Derek J.R. Ransburgh, Alicia Zha, Haritha Mathsyaraja, Sanford H. Barsky, Zeina Kais
PDF file - 2651K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e50a3f394e69f0596c79e26e802983a
https://doi.org/10.1158/1541-7786.22518904.v1
https://doi.org/10.1158/1541-7786.22518904.v1
Autor:
Jeffrey D. Parvin, Amanda Ewart Toland, Chikashi Ishioka, Natsuko Chiba, Derek J.R. Ransburgh
Supplementary Table 1 from Identification of Breast Tumor Mutations in BRCA1 That Abolish Its Function in Homologous DNA Recombination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23414d9177713cc888a361fcbcb01ae7
https://doi.org/10.1158/0008-5472.22385598
https://doi.org/10.1158/0008-5472.22385598
Autor:
Jie Zhang, Chikashi Ishioka, Derek J.R. Ransburgh, Amanda E. Toland, Natsuko Chiba, Jeffrey D. Parvin, William I. Towler
Missense substitutions of uncertain clinical significance in the BRCA1 gene are a vexing problem in genetic counseling for women who have a family history of breast cancer. In this study, we evaluated the functions of 29 missense substitutions of BRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8b0cec655bd196fe741dc4aa01197
https://europepmc.org/articles/PMC3906639/
https://europepmc.org/articles/PMC3906639/
Autor:
Gang He, Haritha Mathsyaraja, Zeina Kais, Charles L. Shapiro, Robert Pilarski, Kun Huang, Alicia Zha, Sanford H. Barsky, Derek J.R. Ransburgh, Jeffrey D. Parvin
To find genes and proteins that collaborate with BRCA1 or BRCA2 in the pathogenesis of breast cancer, we used an informatics approach and found a candidate BRCA interactor, KIAA0101, to function like BRCA1 in exerting a powerful control over centroso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aec831d8cb35a3ec01e99b48b05d1e
https://europepmc.org/articles/PMC3157549/
https://europepmc.org/articles/PMC3157549/
Publikováno v:
Cancer research. 70(3)
There have been few published analyses of the effects of missense mutations of the BRCA1 gene on BRCA1 protein function. In this study, we adapted a previously described homology directed recombination (HDR) assay to the analysis of the effects of BR
Autor:
Mansi Arora, Shweta Kotian, Alicia Zha, Ümit V. Çatalyürek, Jeffrey D. Parvin, Kun Huang, Zeina Kais, Derek J.R. Ransburgh, Doruk Bozdağ
Publikováno v:
2009 Ohio Collaborative Conference on Bioinformatics.
We are developing a new framework for discovery of genes involved in the breast carcinogenesis process. Among families that have a predisposition to breast cancer, approximately 25% have inherited mutations in either breast cancer associated (“BRCA