Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Derek J. Hoelz"'
Autor:
J. Jefferson P. Perry, Gregory D. Ballard, Alexandra E. Albert, Lacey E. Dobrolecki, Linda H. Malkas, Derek J. Hoelz
Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1288-1296 (2015)
Recent evidence supports the presence of an L-glutamyl methyltransferase(s) in eukaryotic cells, but this enzyme class has been defined only in certain prokaryotic species. Here, we characterize the human C6orf211 gene product as “acidic residue me
Externí odkaz:
https://doaj.org/article/54bf9a26fd9a40c8872d772b1de1cad2
Autor:
Linda H. Malkas, Robert J. Hickey, Katharyn E. Turner, John A. Sandoval, Frederick J. Rescorla, Hari R. Kumar, Xiaoling Zhong, Derek J. Hoelz
Publikováno v:
Journal of Surgical Research. 156:116-122
Background Children with advanced-stage neuroblastoma (NB) traditionally experience poor outcomes. Because early detection of advanced-stage disease may impact survival, finding new targets for early diagnosis is crucial. Evidence suggests the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada5eccf1cdefc78ab5066bc1f3c3eb8
https://doi.org/10.1016/j.jss.2009.02.019
https://doi.org/10.1016/j.jss.2009.02.019
Autor:
Frederick J. Rescorla, Hari R. Kumar, Robert J. Hickey, Xiaoling Zhong, Linda H. Malkas, John A. Sandoval, Derek J. Hoelz
Publikováno v:
Pediatric Blood & Cancer. 53:332-337
Neuroblastoma (NB) is the most common extracranial solidtumorinchildren [1],originatingfromneuralcrestcellsandusuallymanifesting in the sympathetic nervous system, including theadrenalmedulla,sympatheticganglia,andparaganglia.NBpatientsareassignedtoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c226e02f51b2e9f42b1fab6f95f0960
https://doi.org/10.1002/pbc.22068
https://doi.org/10.1002/pbc.22068
Autor:
Robert J. Hickey, Frederick J. Rescorla, Katharyn E. Turner, Linda H. Malkas, Derek J. Hoelz, John A. Sandoval
Publikováno v:
Journal of Surgical Research. 142:268-274
Introduction. Development of early detection assays for advanced stage neuroblastoma (NB) remains elusive. We have previously shown that serum protein profiling technologies can differentiate healthy from NB children. As various sources of patient re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bb766e2b09d82cbbf2fb53dff2d3d0
https://doi.org/10.1016/j.jss.2007.03.058
https://doi.org/10.1016/j.jss.2007.03.058
Autor:
Frederick J. Rescorla, Linda H. Malkas, John A. Sandoval, Derek J. Hoelz, Katharyn E. Turner, Andrew C. Eppstein, Jared H. Linebarger, Patrick J. Klein, Christian M. Schmidt, Robert J. Hickey
Publikováno v:
Journal of Surgical Research. 134:61-67
Introduction Survival for high-risk neuroblastoma (NB) remains poor despite aggressive therapy. Novel therapies are vital for improving prognosis. We previously showed differential NB subtype sensitivity to p42/44 mitogen-activated protein kinase (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569da728c69d7f509e2f6c493d3bafa6
https://doi.org/10.1016/j.jss.2006.02.011
https://doi.org/10.1016/j.jss.2006.02.011
Autor:
Derek J. Hoelz, Jeffrey Huang, Lacey E. Dobrolecki, Sreemala Murthy, Agasanur K. Prahalad, Janet M. Hock, Therry Winata, Robert J. Hickey
Publikováno v:
PROTEOMICS. 6:3482-3493
Parathyroid hormone (amino acids 1–34) (PTH) regulates bone and calcium homeostasis. The magnitude of the effects of PTH on bone varies in osteoporosis patients. We employed ProteinChip ® technology to generate protein profiles from sera of mice t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16019960fe72b52d8ac0102905fe1cb
https://doi.org/10.1002/pmic.200500929
https://doi.org/10.1002/pmic.200500929
Autor:
Xiaoling, Zhong, Derek J, Hoelz, Hari R, Kumar, John A, Sandoval, Frederick J, Rescorla, Robert J, Hickey, Linda H, Malkas
Publikováno v:
Pediatric bloodcancer. 53(3)
Neuroblastoma (NB) is the most common extracranial solid tumor in children. At the time of diagnosis, the tumor has metastasized in as many as 7 of 10 cases, and survival in high-risk patients remains poor. Accurate classification of high-risk patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b60fe565d83eabe5f6b8ffcbb51c373
https://pubmed.ncbi.nlm.nih.gov/19418541
https://pubmed.ncbi.nlm.nih.gov/19418541
Autor:
Xiaoling Zhong, Linda H. Malkas, John A. Sandoval, Robert J. Hickey, Frederick J. Rescorla, Derek J. Hoelz, Hari R. Kumar
Publikováno v:
Pediatric surgery international. 24(11)
Solid tumors, such as neuroblastoma (NB), are associated with a heterogeneous cell environment. Multicellular tumor spheroid (MCTS) cultures have been shown to better mimic growth characteristics of in vivo solid tumors. Because tumor spheroid growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbb8745b7735dfe015bcb883b88c10b
https://pubmed.ncbi.nlm.nih.gov/18797883
https://pubmed.ncbi.nlm.nih.gov/18797883
Ionizing radiation induces DNA double-strand breaks which are repaired by the nonhomologous end joining (NHEJ) pathway. NHEJ is initiated upon Ku binding to the DNA ends and facilitating an interaction with the DNA-dependent protein kinase catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae783e431bc4d626f3932fc5c595ed8f
https://europepmc.org/articles/PMC2432109/
https://europepmc.org/articles/PMC2432109/
Autor:
Waleed Abdel-Aziz, Milos V. Novotny, Linda H. Malkas, Lacey E. Dobrolecki, Randy J. Arnold, Lauren Schnaper, Robert J. Hickey, Andrew P. Loehrer, Derek J. Hoelz
Publikováno v:
Proteomics. 6(17)
The post-translational modification of proliferating cell nuclear antigen (PCNA) has been implicated in modulating its function for over 20 years. With multiple interacting partners, PCNA is involved in processes ranging from DNA replication and repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3776cf64b3cc14e403ea86913a3f66
https://pubmed.ncbi.nlm.nih.gov/16888766
https://pubmed.ncbi.nlm.nih.gov/16888766