Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Derek J Mattern"'
Autor:
Bastian Jöhnk, Özgür Bayram, Anja Abelmann, Thorsten Heinekamp, Derek J Mattern, Axel A Brakhage, Ilse D Jacobsen, Oliver Valerius, Gerhard H Braus
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005899 (2016)
F-box proteins share the F-box domain to connect substrates of E3 SCF ubiquitin RING ligases through the adaptor Skp1/A to Cul1/A scaffolds. F-box protein Fbx15 is part of the general stress response of the human pathogenic mold Aspergillus fumigatus
Externí odkaz:
https://doaj.org/article/bd08a184dc5046c195448f3d3f138309
Autor:
Tina eNetzker, Juliane eFischer, Jakob eWeber, Derek J Mattern, Claudia C König, Vito eValiante, Volker eSchroeckh, Axel A Brakhage
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Microorganisms form diverse multispecies communities in various ecosystems. The high abundance of fungal and bacterial species in these consortia results in specific communication between the microorganisms. A key role in this communication is played
Externí odkaz:
https://doaj.org/article/019ea00b15cb4d3187f74d42b72cf7a2
Autor:
Alexander U. Bissell, Julia Rautschek, Sandra Hoefgen, Luka Raguž, Derek J. Mattern, Nauman Saeed, Slavica Janevska, Katarina Jojić, Ying Huang, Johann E. Kufs, Barbara Herboeck, Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Publikováno v:
ACS Chem Biol
Sphingofungins belong to a group of structurally related sphingolipid inhibitors produced by fungi, which specifically inhibit serine palmitoyl transferases, enzymes catalyzing the initial step during sphingolipid biosynthesis. Sphingolipids are inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e19c2f19eac7bad1e98affc3aca96a
https://doi.org/10.1021/acschembio.1c00839
https://doi.org/10.1021/acschembio.1c00839
Autor:
Maria Mittag, Derek J. Mattern, Michal Flak, Mario K. C. Krespach, Axel A. Brakhage, María García-Altares, Volker Schroeckh, Anica Schmalzl, Hanno Schoeler, Kirstin Scherlach, Tina Netzker, Anna J Komor, Christian Hertweck
Publikováno v:
The ISME Journal
Organismal interactions within microbial consortia and their responses to harmful intruders remain largely understudied. An important step toward the goal of understanding functional ecological interactions and their evolutionary selection is the stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b8874fd13a99d137205c40fff79584
http://europepmc.org/articles/PMC7784976
http://europepmc.org/articles/PMC7784976
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Synthetic biology is an ever-expanding field in science, also encompassing the research area of fungal natural product discovery and production. Until now, different aspects of synthetic biology have been covered in fungal natural product studies fro
Externí odkaz:
https://doaj.org/article/e9d9c25fe5044d9e96d76744bae10640
Autor:
Derek J. Mattern, Axel A. Brakhage, Sandra Hoefgen, Maria C. Stroe, Johann E. Kufs, Janis Fricke, Peter Hortschansky, Vito Valiante, Jun Lin, Dirk Hoffmeister
Publikováno v:
Metabolic Engineering. 48:44-51
Heterologous expression of multi-gene biosynthetic pathways in eukaryotic hosts is limited by highly regulated individual monocistrons. Dissimilar to prokaryotes, each eukaryotic gene is strictly controlled by its own regulatory elements, such as pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7702e41ce6e128f56cea5d2ece2f11c6
https://doi.org/10.1016/j.ymben.2018.05.014
https://doi.org/10.1016/j.ymben.2018.05.014
Autor:
Eckhard Thines, Christian Hertweck, Anja Schüffler, Derek J. Mattern, Fabian Horn, Markus Nett, Reinhard Guthke, Grit Walther, Joachim Dickhaut, Lutz Petzke, Vito Valiante, Axel A. Brakhage, Kirstin Scherlach
Publikováno v:
ACS Chemical Biology
Filamentous fungi produce a wide range of natural products that are commonly used in various industrial contexts (e.g., pharmaceuticals and insecticides). Meroterpenoids are natural products of interest because of their various biological activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366c0ad66ed2dba4df27512605337fe4
https://doi.org/10.1021/acschembio.7b00003
https://doi.org/10.1021/acschembio.7b00003
Autor:
Jakob Weber, Rebecca A. Slotkowski, Axel A. Brakhage, Derek J. Mattern, Uffe Hasbro Mortensen, Vito Valiante, Christina Spuur Nødvig
Publikováno v:
ACS Synthetic Biology. 6:62-68
Filamentous fungi produce varieties of natural products even in a strain dependent manner. However, the genetic basis of chemical speciation between strains is still widely unknown. One example is trypacidin, a natural product of the opportunistic hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646e11ac36470a472e5ae3f8dc1eda7f
https://doi.org/10.1021/acssynbio.6b00203
https://doi.org/10.1021/acssynbio.6b00203
Autor:
Axel A. Brakhage, Kristin Kroll, Maria Strassburger, Ekaterina Shelest, Andreas Thywissen, Derek J. Mattern, Olaf Kniemeyer, Ilse D. Jacobsen, Elena Shekhova, Thorsten Heinekamp
Publikováno v:
Molecular Microbiology. 101:92-108
Aspergillus fumigatus is the predominant airborne pathogenic fungus causing invasive aspergillosis in immunocompromised patients. During infection A. fumigatus has to adapt to oxygen-limiting conditions in inflammatory or necrotic tissue. Previously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3894d64514ef66448e7e30e121002921
https://doi.org/10.1111/mmi.13377
https://doi.org/10.1111/mmi.13377
Autor:
Vito Valiante, Jörg Linde, Olaf Kniemeyer, Reinhard Guthke, Theresia Conrad, Ilse D. Jacobsen, Derek J. Mattern, Sebastian Vlaic, Thomas Krüger, Axel A. Brakhage, Sebastian G. Henkel
Publikováno v:
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss 1, Pp 1-18 (2018)
BMC Systems Biology, Vol 12, Iss 1, Pp 1-18 (2018)
Background Omics data provide deep insights into overall biological processes of organisms. However, integration of data from different molecular levels such as transcriptomics and proteomics, still remains challenging. Analyzing lists of differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7181e0d8ae40986e901bef6e9bfeab3
https://pubmed.ncbi.nlm.nih.gov/30342519
https://pubmed.ncbi.nlm.nih.gov/30342519