Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Derek Franklin"'
1
Akademický článek
Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway
Autor: Derek Franklin, Yanping Zhang
Publikováno v: Molecular & Cellular Oncology, Vol 5, Iss 3 (2018)
Nutrient availability alters ribosomal biogenesis, causing ribosomal proteins to act as secondary messengers of nutrient response by binding to MDM2 and activating p53. Recent work suggests that the ribosomal protein (RP)-MDM2-p53 pathway responds to
Externí odkaz: https://doaj.org/article/df873450e1ec43a2813baf02287dce7e
Zobrazit plný text záznamu
3
Abstract 1815: Rapid serial killing of target cells by Vγ9Vδ2 T Cells in cynomolgus macaques and humanized mice treated with a CD20-directed heterodimeric butyrophilin 2A1/3A1 fusion protein
Autor: Anne Y. Lai, Louis E. Gonzalez, Noah Murr, Karen Lenz, Derek Franklin, Kristen Campbell, Faraha Brewer, Arpita Patel, Kinsley Evans, Mahmud Hussein, Keith Wilson, George Fromm, Taylor H. Schreiber, Suresh de Silva
Publikováno v: Cancer Research. 83:1815-1815
CD3-directed T cell engagers provide clinical benefit in a variety of hematologic cancers, but it remains unclear whether γδ T cells (GDT) are present at sufficient numbers to be similarly harnessed because they represent only 1-5% of the total T c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7564e2260e28fd9e3bfcfba94f03369
https://doi.org/10.1158/1538-7445.am2023-1815
Zobrazit plný text záznamu
4
Exploring the adoption and expression of subcultural identities among gay, bisexual, and queer-identifying men in Australia
Autor: Adam Bourne, Anthony Lyons, Jake Derek Franklin
Publikováno v: Current Psychology.
Gay, bisexual, and queer-identifying (GBQ) communities tend to comprise various subcultural identity groups based around shared practices and intersectional identities, but little research has sought to qualitatively understand how these identities a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5e1c20add9bf49c4f89fd4c8ff15e05
https://doi.org/10.1007/s12144-022-02948-9
Zobrazit plný text záznamu
5
Phenomenological study exploring ethics in prehospital research from the paramedic’s perspective: experiences from the Paramedic-2 trial in a UK ambulance service
Autor: John Derek Franklin, Rebekah McNaughton, Karl Charlton
Publikováno v: Emergency Medicine Journal. 36:535-540
ObjectivesWe set out to investigate paramedics’ views of ethics and research, drawing on experiences from Paramedic-2, a randomised controlled trial comparing epinephrine and placebo in out-of-hospital cardiac arrest (OHCA).MethodsAn interpretative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc17d4bc719b8307b8be205d9b4cfa8
https://doi.org/10.1136/emermed-2019-208556
Zobrazit plný text záznamu
6
Peak Oxygen Uptake in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Meta-Analysis
Autor: Greg Atkinson, Alan M. Batterham, John Derek Franklin, Janet M. Atkinson
Publikováno v: International Journal of Sports Medicine. 40:77-87
To evaluate the magnitude of the difference in VO2peak between patients with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) and apparently healthy controls, 7 databases (Cochrane, PubMed, PsycINFO, Web of Knowledge, Embase, Scopus, Medl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e941e3b9967a9349aecdf19e3fa85ee1
https://doi.org/10.1055/a-0802-9175
Zobrazit plný text záznamu
7
A Universal Mechanism for N2 Binding to and Differing Reactivity of the E4(4H) State of Mo-, V-, and Fe-Nitrogenases
Autor: Harris, Derek Franklin
Publikováno v: All Graduate Theses and Dissertations
As a basic building block in many biological molecules, the element nitrogen (N) is essential for life. Dinitrogen (N2) is abundant in Earth’s atmosphere, but this form is biologically unavailable. To be biologically available, N2 must undergo a re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3486f595a3f4a22fee5bb0bd12609dd2
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=8685&context=etd
Zobrazit plný text záznamu
8
Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex
Autor: Mohamed Salah, Rezk, Mohammad, Abdel-Halim, Adam, Keeton, Derek, Franklin, Matthias, Bauer, Frank Michael, Boeckler, Matthias, Engel, Rolf Wolfgang, Hartmann, Yanping, Zhang, Gary Anthony, Piazza, Ashraf Hassan, Abadi
Publikováno v: Chemicalpharmaceutical bulletin. 64(1)
Twelve derivatives of the general formula 3-substituted-6-chloroindoles were synthesized and tested for their growth inhibitory effects versus p53(+/+) colorectal cancer HCT116 and its p53 knockout isogenic cells; colorectal cancer cell p53(-/-) SW48
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11f1d7ef54d3a8e467065048ce03b97e
https://pubmed.ncbi.nlm.nih.gov/26726742
Zobrazit plný text záznamu
10
Dissertation/ Thesis
A Universal Mechanism for N2 Binding to and Differing Reactivity of the E4(4H) State of Mo-, V-, and Fe-Nitrogenases
Autor: Harris, Derek Franklin
Publikováno v: All Graduate Theses and Dissertations.
As a basic building block in many biological molecules, the element nitrogen (N) is essential for life. Dinitrogen (N2) is abundant in Earth’s atmosphere, but this form is biologically unavailable. To be biologically available, N2 must undergo a re
Externí odkaz: https://digitalcommons.usu.edu/etd/7556
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=8685&context=etd
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje