Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Derek C. Church"'
Autor:
Derek C. Church, Elizabathe Davis, Adam A. Caparco, Lauren Takiguchi, Young Hun Chung, Nicole F. Steinmetz, Jonathan K. Pokorski
Publikováno v:
Cell reports. Physical science, vol 3, iss 10
Protein-polymer conjugates (PPCs) improve therapeutic efficacy of proteins and have been widely used for the treatment of various diseases such as cancer, diabetes, and hepatitis. PEGylation is considered as the "gold standard" in bioconjugation, alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cc794e645ededd9869a1084cef043c
https://escholarship.org/uc/item/75q48653
https://escholarship.org/uc/item/75q48653
Autor:
Isaac Marks, Jonathan K. Pokorski, Soo-Khim Chan, Nicole F. Steinmetz, Sourabh Shukla, Derek C. Church
Publikováno v:
Rsc Advances
RSC advances, vol 11, iss 33
RSC advances, vol 11, iss 33
Prostate-specific membrane antigen (PSMA) is a membrane-bound protein that is preferentially expressed in the prostate gland and induced in many prostate cancers, making it an important target for new diagnostics and therapeutics. To improve the effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60594ca2e3a4a487266eb3a905061754
http://europepmc.org/articles/PMC8180379
http://europepmc.org/articles/PMC8180379
Publikováno v:
ACS macro letters. 3(7)
The effect of star versus linear polymer architecture on the rates of mechanochemically induced bond scission has been explored. We determined rate constants for chain scission of parent linear and star polymers, from which daughter fragments were cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bfe823859041508366eb5c24daac62
https://pubmed.ncbi.nlm.nih.gov/35590762
https://pubmed.ncbi.nlm.nih.gov/35590762
Autor:
Jonathan K. Pokorski, Derek C. Church, Justin D. Hochberg, Sofia Gandarilla, David M. Wirth, Anna Jaquez
Publikováno v:
ACS Applied Materials & Interfaces. 12:19033-19043
In modern manufacturing, it is a widely accepted limitation that the parts patterned by an additive or subtractive manufacturing process (i.e., a lathe, mill, or 3D printer) must be smaller than the machine itself that produced them. Once such parts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850db5557b8f4cbfba7eeea13cfd90c3
https://doi.org/10.1021/acsami.0c02683
https://doi.org/10.1021/acsami.0c02683
Publikováno v:
Adv Funct Mater
Progress in the field of soft devices-i.e., haptics, robotics, and human-machine interfaces (HRHMIs)-has its basis in the science of polymeric materials and chemical synthesis. However, in examining the relevant literature, we find that most developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a98346640c7c4dd5203a5c37107fac
https://europepmc.org/articles/PMC8673772/
https://europepmc.org/articles/PMC8673772/
Publikováno v:
Macromolecular bioscience. 21(7)
Antibiotic-loaded poly(methyl methacrylate) (PMMA) cement is commonly used as a local delivery system to treat and prevent orthopedic infections associated with arthroplasties in load-bearing applications. However, these delivery systems are ineffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2d977724e85501b15f77765d8fc512
https://pubmed.ncbi.nlm.nih.gov/33885231
https://pubmed.ncbi.nlm.nih.gov/33885231
Autor:
Derek C. Church, Jonathan K. Pokorski
Publikováno v:
Angewandte Chemie (International ed. in English), vol 59, iss 28
Angew Chem Int Ed Engl
Angew Chem Int Ed Engl
Cell-based therapies are gaining prominence in treating a wide variety of diseases and using synthetic polymers to manipulate these cells provides an opportunity to impart function that could not be achieved using solely genetic means. Herein, we des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2e3720e8ba0c092a65b6a4c08ab01c
https://escholarship.org/uc/item/5287b172
https://escholarship.org/uc/item/5287b172
Publikováno v:
Polym Chem
Polymer chemistry, vol 11, iss 27
Polymer chemistry, vol 11, iss 27
Ring opening metathesis polymerization (ROMP) is widely considered an excellent living polymerization technique that proceeds rapidly under ambient conditions and is highly functional group tolerant when performed in organic solvents. However, achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcd63620baf83263d24efa6589c2259
https://europepmc.org/articles/PMC8009303/
https://europepmc.org/articles/PMC8009303/
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12094 (2010)
BACKGROUND: In symbiotic legume nodules, endosymbiotic rhizobia (bacteroids) fix atmospheric N(2), an ATP-dependent catalytic process yielding stoichiometric ammonium and hydrogen gas (H(2)). While in most legume nodules this H(2) is quantitatively e
Externí odkaz:
https://doaj.org/article/c7289245c16f46db82c3c8afe210ba52
Autor:
Chang-Uk Lee, Andrew J. Boydston, Saghar Nourian, John P. Toscano, Neal A. Yakelis, Derek C. Church
Publikováno v:
ACS Macro Letters. 6:46-49
We demonstrate concomitant release of HNO and small molecule organics from amphiphilic poly(norbornene)-based copolymers. This key function was achieved by incorporation of thermally labile oxazine units within random and block copolymer architecture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb5c78d14027cec9bdb401e720c3396
https://doi.org/10.1021/acsmacrolett.6b00887
https://doi.org/10.1021/acsmacrolett.6b00887