Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Derek C Molliver"'
Autor:
Ting Wang, Derek C Molliver, Xiaotang Jing, Erica S Schwartz, Fu-Chia Yang, Omar Abdel Samad, Qiufu Ma, Brian M Davis
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28908 (2011)
In adult mammals, the phenotype of half of all pain-sensing (nociceptive) sensory neurons is tonically modulated by growth factors in the glial cell line-derived neurotrophic factor (GDNF) family that includes GDNF, artemin (ARTN) and neurturin (NRTN
Externí odkaz:
https://doaj.org/article/d569b5f849fe406e9a27294cee37ad64
Autor:
Derek C. Molliver, Peter Neufeld, Eliza Grlickova-Duzevik, Benjamin J. Harrison, Aidan McGrath-Conwell, Merilla Michael, Thomas M. Reimonn
Primary sensory Dorsal Root Ganglia (DRG) neurons are diverse, with distinct populations that respond to specific stimuli. Previously, we observed that functionally distinct populations of DRG neurons express mRNA transcript variants with different 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c088941471d7eba28f29d55ef94abd3
https://doi.org/10.1101/2021.07.05.451166
https://doi.org/10.1101/2021.07.05.451166
Autor:
Derek C. Molliver, Diana J. Goode
Publikováno v:
J Neurosci
Gαs-coupled receptors signaling through cAMP provide a key mechanism for the sensitization of nociceptive sensory neurons, and the cAMP effector Epac has been implicated in the transition from acute to chronic pain. Epac exerts its effects through R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11883db802f7d3596a5c17639a7ecfd
https://europepmc.org/articles/PMC8018894/
https://europepmc.org/articles/PMC8018894/
Publikováno v:
The Journal of Pain. 23:26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9250ba29f1dd3fbdeb3fdc8e8970838
https://doi.org/10.1016/j.jpain.2022.03.101
https://doi.org/10.1016/j.jpain.2022.03.101
Autor:
Diana J. Goode, Derek C. Molliver
Publikováno v:
Mol Cell Biochem
Exchange protein directly activated by cAMP (Epac) and protein kinase A are effectors for cAMP with distinct actions and regulatory mechanisms. Epac is a Rap guanine nucleotide exchange factor that activates Rap1; protein kinase C (PKC) is a major do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6fe76ad9dec4fdad56675ebd05a824
https://europepmc.org/articles/PMC7269517/
https://europepmc.org/articles/PMC7269517/
Autor:
Kristofer K. Rau, Michael P. Jankowski, H. Richard Koerber, Derek C. Molliver, Kyle M. Baumbauer, Deepak J. Soneji
Publikováno v:
Neuroscience. 332:223-230
P2Y 2 is a member of the P2Y family of G protein-coupled nucleotide receptors that is widely co-expressed with TRPV1 in peripheral sensory neurons of the dorsal root ganglia. To characterize P2Y 2 function in cutaneous afferents, intracellular record
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e20ee32baef8feb1bfbb158a16b96e0
https://doi.org/10.1016/j.neuroscience.2016.06.054
https://doi.org/10.1016/j.neuroscience.2016.06.054
Autor:
Courtney A. Rieder, Ryan F. Relich, James Vaughn, Sebastién Sannajust, Jonathan Rieder, Meghan May, Diana J. Goode, Tamara E. King, Derek C. Molliver, Ramaz Geguchadze
Publikováno v:
Viruses
Volume 11
Issue 12
Volume 11
Issue 12
Zika virus (ZIKV) recently emerged in the Western Hemisphere with previously unrecognized or unreported clinical presentations. Here, we identify two putative binding mechanisms of ancestral and emergent ZIKV strains featuring the envelope (E) protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d26131d676fb05313425a2ac206f01
https://doi.org/10.3390/v11121101
https://doi.org/10.3390/v11121101
Autor:
Jennifer J. DeBerry, Xiaotang Jing, Ting Wang, Kathryn M. Albers, Brian M. Davis, Derek C. Molliver, Erica S. Schwartz
Publikováno v:
The Journal of Neuroscience. 33:2060-2070
Neurturin (NRTN) is a member of the glial cell line-derived neurotrophic factor family of ligands that exerts its actions via Ret tyrosine kinase and GFRα2. Expression of the Ret–GFRα2 coreceptor complex is primarily restricted to the peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0212ca9c18e860f7abbfb38505802d81
https://doi.org/10.1523/jneurosci.4012-12.2013
https://doi.org/10.1523/jneurosci.4012-12.2013
Publikováno v:
Neuroscience. 193:387-398
Nucleotide-activated P2X channels and P2Y metabotropic receptors participate in nociceptive signaling. Agonist availability is regulated by nucleoside triphosphate diphosphohydrolase-1 (NTPDase) -1, -2, -3 and -8, a family of enzymes that hydrolyze e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77913e41c11abcd6e41bc30f068b3cb8
https://doi.org/10.1016/j.neuroscience.2011.07.044
https://doi.org/10.1016/j.neuroscience.2011.07.044
Autor:
Erica S. Schwartz, Derek C. Molliver, Brian M. Davis, Kathryn M. Albers, Pam Cornuet, Julie A. Christianson, Sacha A. Malin
Publikováno v:
Journal of Neuroscience. 31:10516-10528
The nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) families of growth factors regulate the sensitivity of sensory neurons. The ion channels transient receptor potential vanilloid 1 (TRPV1) and transient receptor pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb01083e040a0f424affb874ce05a00
https://doi.org/10.1523/jneurosci.2992-10.2011
https://doi.org/10.1523/jneurosci.2992-10.2011