Zobrazeno 1 - 10
of 768
pro vyhledávání: '"Derek C Angus"'
Autor:
Alexander Zarbock, Pierre-François Laterre, Peter Pickkers, Rinaldo Bellomo, Paul Young, Derek C Angus, Kent Doi, Michael Joannidis, Marlies Ostermann, Morten Bestle, Ravindra L Mehta, Patrick T Murray, John A Kellum, Jacques Arend, Christopher J Doig, Ville Pettilä, Bruno Francois, Erik van den Berg, Juliane Bernholz, Kristine Broglio, Jan Carlsen, Ricard Ferrer, Kathleen Liu, Sharon Richards, Anne Louise Kjølbye
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction Sepsis, the leading cause of acute kidney injury (AKI), is associated with a high morbidity and mortality. Alkaline phosphatase (ALP) is an endogenous detoxifying enzyme. A recombinant human ALP compound, ilofotase alfa, showed no safety
Externí odkaz:
https://doaj.org/article/409c425fa54047969891edcb40c58ebb
Autor:
Derek C Angus, Jennifer Holder-Murray, Katherine Moll Reitz, Christopher W Seymour, Jennifer Vates, Melanie Quintana, Kert Viele, Michelle Detry, Michael Morowitz, Alison Morris, Barbara Methe, Jason Kennedy, Brian Zuckerbraun, Timothy D Girard, Oscar C Marroquin, Stephen Esper, Anne B Newman, Scott Berry, Matthew Neal
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Introduction As the population ages, there is interest in strategies to promote resiliency, especially for frail patients at risk of its complications. The physiological stress of surgery in high-risk individuals has been proposed both as an importan
Externí odkaz:
https://doaj.org/article/b9c524c0611f41caaeb63d568cb8ea1b
Autor:
Derek C Angus, Robert M Arnold, Susan Martin, Taylor Lincoln, Anne-Marie Shields, Praewpannarai Buddadhumaruk, Chung-Chou H Chang, Francis Pike, Hsiangyu Chen, Elke Brown, Veronica Kozar, Caroline Pidro, Jeremy M Kahn, Joseph M Darby, Douglas B White
Publikováno v:
BMJ Open, Vol 10, Iss 3 (2020)
IntroductionAlthough shortcomings in clinician–family communication and decision making for incapacitated, critically ill patients are common, there are few rigorously tested interventions to improve outcomes. In this manuscript, we present our met
Externí odkaz:
https://doaj.org/article/cf27d8ede4864393bc7df7d2c4c1a09e
Autor:
Veli Bakalov, Laura Reyes-Uribe, Rahul Deshpande, Abigail L Maloy, Steven D Shapiro, Derek C Angus, Chung-Chou H Chang, Laurence Le Moyec, Stacy Gelhaus Wendell, Ata Murat Kaynar
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241122 (2020)
Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation. Metabolic shift from oxidative phosphorylation to aerobic glycolysis links metabolism
Externí odkaz:
https://doaj.org/article/843e84419682472690593041bb68aea3
Autor:
Shreyus S Kulkarni, Barry Dewitt, Baruch Fischhoff, Matthew R Rosengart, Derek C Angus, Melissa Saul, Donald M Yealy, Deepika Mohan
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212201 (2019)
BACKGROUND:Under-triage of severely injured patients presenting to non-trauma centers (failure to transfer to a trauma center) remains problematic despite quality improvement efforts. Insights from the behavioral science literature suggest that physi
Externí odkaz:
https://doaj.org/article/a870ed321555454fbe800f4d51c86461
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198269 (2018)
BACKGROUND:Several studies have shown that long-term survival after acute kidney injury (AKI) is reduced even if there is clinical recovery. However, we recently reported that in septic shock patients those that recover from AKI have survival similar
Externí odkaz:
https://doaj.org/article/62f37cc4ee944d4c9cb0018d7b6f11d5
Autor:
Christopher M. Horvat, Srinivasan Suresh, Nathan James, Rajesh K. Aneja, Alicia K. Au, Scott Berry, Arthur Blumer, Kelly Bricker, Robert S. B. Clark, Heidilyn Dolinich, Sheila Hahner, Christina Jockel, Jordan Kalivoda, India Loar, Denee Marasco, Adrienne Marcinick, Oscar Marroquin, Jonathan O’brien, Jonathan Pelletier, Sriram Ramgopal, Shekhar Venkataraman, Derek C. Angus, Gabriella Butler
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background High flow nasal cannula (HFNC) has been increasingly adopted in the past 2 decades as a mode of respiratory support for children hospitalized with bronchiolitis. The growing use of HFNC despite a paucity of high-quality data regar
Externí odkaz:
https://doaj.org/article/16f6685ac75447f8b83705c00b600fc4
Autor:
Sarah K. Andersen, Chung-Chou H. Chang, Robert M. Arnold, Caroline Pidro, Joseph M. Darby, Derek C. Angus, Douglas B. White, the Pairing Re-engineered Intensive Care Teams with Nurse-driven Emotional Support, Relationship building (PARTNER) Investigators
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Patients with advanced critical illness often receive more intensive treatment than they would choose for themselves, which contributes to high health care costs near the end of life. The purpose of this study was to determine whe
Externí odkaz:
https://doaj.org/article/d1670b163920438d80766f8f22c43f95
Autor:
Kimberley M. DeMerle, Jason N. Kennedy, Chung-Chou H. Chang, Kevin Delucchi, David T. Huang, Max S. Kravitz, Nathan I. Shapiro, Donald M. Yealy, Derek C. Angus, Carolyn S. Calfee, Christopher W. Seymour
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Sepsis is a heterogeneous syndrome and phenotypes have been proposed using clinical data. Less is known about the contribution of protein biomarkers to clinical sepsis phenotypes and their importance for treatment effects in randomized trial
Externí odkaz:
https://doaj.org/article/ae5cd33625854879aaa5420c4d272404
Autor:
Deepika Mohan, Derek C. Angus, Chung-Chou H. Chang, Jonathan Elmer, Baruch Fischhoff, Kim J. Rak, Jacqueline L. Barnes, Andrew B. Peitzman, Douglas B. White
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Transfer of severely injured patients to trauma centers, either directly from the field or after evaluation at non-trauma centers, reduces preventable morbidity and mortality. Failure to transfer these patients appropriately (i.e.
Externí odkaz:
https://doaj.org/article/63e7e047afe74c2c8788af7b377612ba