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pro vyhledávání: '"Derek B. Bush"'
Autor:
Bradley C. Bundy, Kristen M. Wilding, Addison K. Smith, Joshua W. Wilkerson, Derek B. Bush, Thomas A. Knotts
Publikováno v:
ACS synthetic biology. 7(2)
Although polyethylene glycol (PEG) is commonly used to improve protein stability and therapeutic efficacy, the optimal location for attaching PEG onto proteins is not well understood. Here, we present a cell-free protein synthesis-based screening pla
Autor:
Derek B. Bush, Thomas A. Knotts
Publikováno v:
The Journal of Chemical Physics. 149:165102
Next generation antibody microarray devices have the potential to outperform current molecular detection methods and realize new applications in medicine, scientific research, and national defense. However, antibody microarrays, or arrays of antibody
Autor:
Thomas A. Knotts, Derek B. Bush
Publikováno v:
The Journal of Chemical Physics. 146:155103
Antibody microarrays have the potential to revolutionize molecular detection for many applications, but their current use is limited by poor reliability, and efforts to change this have not yielded fruitful results. One difficulty which limits the ra
Publikováno v:
Biotechnology progress. 28(2)
Virus-like particles (VLPs) have been employed for a number of nanometric applications because they self-assemble, exhibit a high degree of symmetry, and can be genetically and chemically modified. However, high symmetry does not allow for a single u
Autor:
Derek B. Bush, Thomas A. Knotts
Publikováno v:
The Journal of Chemical Physics. 143:061101
Antibody microarrays have the potential to revolutionize molecular detection in scientific, medical, and other biosensor applications, but their current use is limited because of poor reliability. It is hypothesized that one reason for their poor per