Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Derek B Allison"'
Autor:
Yifan Kong, Chaohao Li, Jinpeng Liu, Sai Wu, Min Zhang, Derek B Allison, Faisal Hassan, Daheng He, Xinyi Wang, Fengyi Mao, Qiongsi Zhang, Yanquan Zhang, Zhiguo Li, Chi Wang, Xiaoqi Liu
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011309 (2024)
PLK1 (Polo-like kinase 1) plays a critical role in the progression of lung adenocarcinoma (LUAD). Recent studies have unveiled that targeting PLK1 improves the efficacy of immunotherapy, highlighting its important role in the regulation of tumor immu
Externí odkaz:
https://doaj.org/article/789fa172eea04daab8fa8f301a589919
Autor:
Chaohao Li, Derek B Allison, Daheng He, Fengyi Mao, Xinyi Wang, Piotr Rychahou, Ibrahim A Imam, Yifan Kong, Qiongsi Zhang, Yanquan Zhang, Jinghui Liu, Ruixin Wang, Xiongjian Rao, Sai Wu, B Mark Evers, Qing Shao, Chi Wang, Zhiguo Li, Xiaoqi Liu
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011017 (2023)
Metastasis of lung adenocarcinoma (LUAD) is a major cause of death in patients. Aryl hydrocarbon receptor (AHR), an important transcription factor, is involved in the initiation and progression of lung cancer. Polo-like kinase 1 (PLK1), a serine/thre
Externí odkaz:
https://doaj.org/article/08cfb26933d841d3937e208ce360b5ec
Autor:
Lyndsay E A Young, Lindsey R Conroy, Harrison A Clarke, Tara R Hawkinson, Kayli E Bolton, William C Sanders, Josephine E Chang, Madison B Webb, Warren J Alilain, Craig W Vander Kooi, Richard R Drake, Douglas A Andres, Tom C Badgett, Lars M Wagner, Derek B Allison, Ramon C Sun, Matthew S Gentry
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 11, Pp n/a-n/a (2022)
Abstract Glycogen dysregulation is a hallmark of aging, and aberrant glycogen drives metabolic reprogramming and pathogenesis in multiple diseases. However, glycogen heterogeneity in healthy and diseased tissues remains largely unknown. Herein, we de
Externí odkaz:
https://doaj.org/article/a448069261be43559f4205eb79956a31
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1394 (2022)
Somatostatin receptors (SSTR) are expressed in various neoplasms and can be targeted for both diagnostics as well as therapeutics. This systematic review aims to compile and discuss the prevalence of somatostatin receptor expression in various neopla
Externí odkaz:
https://doaj.org/article/98eff36171414e5c8f2da0a8f855de36
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 931 (2022)
Since the release of The Paris System for Reporting Urinary Cytology (TPS), the assessment of urine cytology specimens has primarily focused on the detection of high-grade urothelial carcinoma (HGUC) and carcinoma in situ (CIS). Fortunately, the mali
Externí odkaz:
https://doaj.org/article/bfdcb83c79c646c799347c6e8ee74493
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 842 (2022)
Ovarian cancer is the deadliest of all gynecologic malignancies claiming the lives of nearly 14,000 women in the United States annually. Despite therapeutic advances, the ovarian cancer mortality rate has remained stagnant since the 1980’s. The mol
Externí odkaz:
https://doaj.org/article/487d24c9f62748da8595310f21403e91
Publikováno v:
Cytopathology. 34:250-253
Publikováno v:
Seminars in Diagnostic Pathology. 39:394-404
Pathologist-performed fine-needle aspiration, or interventional cytopathology, is a minimally invasive, highly accurate technique for sampling and diagnosing palpable lesions. Utilizing cytomorphologic patterns during rapid onsite evaluation (ROSE) a
Autor:
Zhuangzhuang Zhang, Lijun Cheng, Jie Li, Qi Qiao, Anju Karki, Derek B. Allison, Nuha Shaker, Kunyu Li, Sagar M. Utturkar, Nadia M. Atallah Lanman, Xiongjian Rao, Piotr Rychahou, Daheng He, Stephen F. Konieczny, Chi Wang, Qing Shao, B. Mark Evers, Xiaoqi Liu
Publikováno v:
Cancer Res
Polo-like kinase 1 (Plk1) plays an important role in cell-cycle regulation. Recent work has suggested that Plk1 could be a biomarker of gemcitabine response in pancreatic ductal adenocarcinoma (PDAC). Although targeting Plk1 to treat PDAC has been at
Autor:
Lindsey R. Conroy, Harrison A. Clarke, Derek B. Allison, Samuel Santos Valenca, Qi Sun, Tara R. Hawkinson, Lyndsay E. A. Young, Juanita E. Ferreira, Autumn V. Hammonds, Jaclyn B. Dunne, Robert J. McDonald, Kimberly J. Absher, Brittany E. Dong, Ronald C. Bruntz, Kia H. Markussen, Jelena A. Juras, Warren J. Alilain, Jinze Liu, Matthew S. Gentry, Peggi M. Angel, Christopher M. Waters, Ramon C. Sun
Publikováno v:
Nature Communications. 14
Matrix assisted laser desorption/ionization imaging has greatly improved our understanding of spatial biology, however a robust bioinformatic pipeline for data analysis is lacking. Here, we demonstrate the application of high-dimensionality reduction