Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Derek A. Ganes"'
Autor:
Mario A. Gonzalez, Jennifer B. Dressman, Vivian A. Gray, Vinod P. Shah, Barbara M. Davit, Erika S. Stippler, Douglas F. Smith, Jason T. Chittenden, Glenn A. Van Buskirk, Russell J. Rackley, Rong Li, Theresa Shephard, Avi Yacobi, James E. Polli, David B. Turner, Sandra Suarez-Sharp, Michael B. Bolger, Maziar Kakhi, Derek A. Ganes, Anthony J. DeStefano, John Duan, Tasheen Mirza
Publikováno v:
Dissolution Technologies. 21:51-58
This article summarizes the proceeding of the September 2012 Workshop on Application of In vitro–In vivo correlation (IVIVC) in Formulation Development. The workshop brought together international experts with the goal of establishing common concep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::323a8fd9d667f53128b52021f08319ad
https://doi.org/10.14227/dt210214p51
https://doi.org/10.14227/dt210214p51
Autor:
Mei-Ling Chen, Paul Fackler, Russell Katz, Mario L. Rocci, Prabu Nambiar, Lawrence X. Yu, Mehul Mehta, Bertil Abrahamsson, Vinod P. Shah, Gerard Sanderink, Kamal K. Midha, Suneel K. Gupta, Derek A. Ganes, Yaning Wang, Sheldon H. Preskorn, James Caro, Barbara M. Davit, Dale P. Conner, Robert Temple, Helen Winkle, Colm Farrell, Salomon A Stavchansky, Avinash G. Thombre
Publikováno v:
Clinical Therapeutics. 32:1704-1712
Background: Modified-release (MR) products are complex dosage forms designed to release drug in a controlled manner to achieve the desired efficacy and safety profiles. Inappropriate control of drug release from such products may result in reduced ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec9d2fe1c718785b81efd3385b6f3e1
https://doi.org/10.1016/j.clinthera.2010.09.014
https://doi.org/10.1016/j.clinthera.2010.09.014
Autor:
Barbara M. Davit, Yaning Wang, Vinod P. Shah, Suneel K. Gupta, Derek A. Ganes, Dale P. Conner, Mario L. Rocci, Russell Katz, Prabu Nambiar, James Caro, Lawrence X. Yu, Kamal K. Midha, Mei-Ling Chen, Bertil Abrahamsson, Salomon A Stavchansky, Avinash G. Thombre, Gerard Sanderink, Sheldon H. Preskorn, Paul Fackler, Robert Temple, Helen Winkle, Mehul Mehta, Colm Farrell
Publikováno v:
European Journal of Pharmaceutical Sciences. 40:148-153
Modified release products are complex dosage forms designed to release drug in a controlled manner to achieve desired efficacy and safety. Inappropriate control of drug release from such products may result in reduced efficacy or increased toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb4bee15f0b757a68b8b46c949500f1
https://doi.org/10.1016/j.ejps.2010.03.017
https://doi.org/10.1016/j.ejps.2010.03.017
Autor:
Kamal K. Midha, Mario L. Rocci, Yaning Wang, Lawrence X. Yu, Avinash G. Thombre, Mei-Ling Chen, Russell Katz, Prabu Nambiar, Sheldon H. Preskorn, Helen Winkle, Derek A. Ganes, James Caro, Bertil Abrahamsson, Barbara M. Davit, Salomon A Stavchansky, Gerard Sanderink, Dale P. Conner, Colm Farrell, Paul Fackler, Suneel K. Gupta, Robert Temple, Mehul Mehta, Vinod P. Shah
Publikováno v:
The AAPS journal. 12(3)
Modified release products are complex dosage forms designed to release drug in a controlled manner to achieve desired efficacy and safety. Inappropriate control of drug release from such products may result in reduced efficacy or increased toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d44ebe72d717808bc7fb23aeb3fc1c0
https://pubmed.ncbi.nlm.nih.gov/20440588
https://pubmed.ncbi.nlm.nih.gov/20440588
Autor:
James E. Patrick, Iraida Gonzalez-Younes, John G. Wagner, Derek A. Ganes, Melton B. Affrime, Kamal K. Midha, J. Chris Sackellares, Larry D. Olson
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 19:413-455
When disposition is monoexponential, extravascular concentration-time (C, t) data yield both disposition and absorption parameters, the latter via the Wagner-Nelson method or deconvolution which are equivalent. Classically, when disposition is multie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea059ad1f1effd1135125a9d7c269b2
https://doi.org/10.1007/bf01061665
https://doi.org/10.1007/bf01061665
Publikováno v:
Alcohol and Alcoholism.
Capillary blood alcohol concentrations (BAL) measured in 22 young adult male volunteers each of whom received three different treatments of alcohol (total N = 66) have been related quantitatively to the dose of alcohol ingested. Linear regression wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba056613b7ca93d493f78544b4882413
https://doi.org/10.1093/oxfordjournals.alcalc.a045019
https://doi.org/10.1093/oxfordjournals.alcalc.a045019
Autor:
Patricia Terrio, Derek A. Ganes, James A. Knol, Zhaomin Yang, Suzette C. Walker-Andrews, John G. Wagner, William D. Ensminger, Philip L. Stetson, Norma J. Johnson, Diane M. Prieskorn, James C. Andrews, Conrad A. Knutsen
Publikováno v:
Selective Cancer Therapeutics. 5:193-203
We have previously shown that 5-fluorouracil (FUra) in humans obeys Michaelis-Menten elimination kinetics. In this article we show that the related bromine and iodine-containing analogs in animals obey similar kinetics. Steady-state arterial (CssA) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473ae44fd4c8e309dc93a5ac451aa04c
https://doi.org/10.1089/sct.1989.5.193
https://doi.org/10.1089/sct.1989.5.193
Autor:
Derek A. Ganes, John G. Wagner
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 432:233-242
A sensitive and specific procedure using high-performance liquid chromatography (HPLC) was developed for the quantification of 5-bromo-2′-deoxyuridine (BUdR) and 5-bromouracil (BU) in plasma. BUdR and BU were first extracted with a mixture of ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349b047237535a54aa455bf4c21d231e
https://doi.org/10.1016/s0378-4347(00)80648-9
https://doi.org/10.1016/s0378-4347(00)80648-9
Publikováno v:
Alcohol and Alcoholism. 24:555-564
Seventy-four (44 under fasting conditions and 30 following oral liquid meals) sets of post-absorptive human capillary blood alcohol concentration-time data were computer-fitted to the integrated form of the Michaelis-Menten equation by numerical inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6b0b8c3452cec1e72f99c7a6f099b5
https://doi.org/10.1093/oxfordjournals.alcalc.a044959
https://doi.org/10.1093/oxfordjournals.alcalc.a044959
Autor:
Derek A. Ganes, David L. Keegan, E. D. Korchinski, Gordon McKay, Edward M. Hawes, Kamal K. Midha, B.S. Chakraborty, John W. Hubbard
Publikováno v:
Journal of Clinical Psychopharmacology. 9:98-104
Single oral doses (5 mg) of haloperidol were administered to 36 healthy men (26 black, 10 white) of whom 28 (22 black, 6 white) completed the study. Plasma samples harvested over 96 hours were analyzed for haloperidol and reduced haloperidol by means
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc9f02798605e1562c204ca0047ab55
https://doi.org/10.1097/00004714-198904000-00005
https://doi.org/10.1097/00004714-198904000-00005