Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Derek A, Pociask"'
Autor:
Chenxiao Wang, Mst Shamima Khatun, Zhe Zhang, Michaela J. Allen, Zheng Chen, Calder R. Ellsworth, Joshua M. Currey, Guixiang Dai, Di Tian, Konrad Bach, Xiao-Ming Yin, Vicki Traina-Dorge, Jay Rappaport, Nicholas J. Maness, Robert V. Blair, Jay K. Kolls, Derek A. Pociask, Xuebin Qin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 infection can cause persistent respiratory sequelae. However, the underlying mechanisms remain unclear. Here we report that sub-lethally infected K18-human ACE2 mice show patchy pneumonia associated with histiocytic inflammation a
Externí odkaz:
https://doaj.org/article/15de162092a24f62b3a66615cbf80085
Autor:
Apoorva Mulay, Bindu Konda, Gustavo Garcia, Jr., Changfu Yao, Stephen Beil, Jaquelyn M. Villalba, Colin Koziol, Chandani Sen, Arunima Purkayastha, Jay. K. Kolls, Derek A. Pociask, Patrizia Pessina, Julio Sainz de Aja, Carolina Garcia-de-Alba, Carla F. Kim, Brigitte Gomperts, Vaithilingaraja Arumugaswami, Barry R. Stripp
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109055- (2021)
Summary: Coronavirus disease 2019 (COVID-19) is the latest respiratory pandemic caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although infection initiates in the proximal airways, severe and sometimes fatal symptoms
Externí odkaz:
https://doaj.org/article/c6b335eff48e42068ebd55ba5f9b3751
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1178-1179
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 3 (2016)
Interleukin (IL)-22 is a member of the IL-10 family of cytokines that has been extensively studied since its discovery in 2000. This review article aims to describe the cellular sources and signaling pathways of this cytokine as well as the functions
Externí odkaz:
https://doaj.org/article/c4d074f64f7f4d9b997e7dd274fd4cdf
Autor:
Kong Chen, Derek A Pociask, Jeremy P McAleer, Yvonne R Chan, John F Alcorn, James L Kreindler, Matthew R Keyser, Steven D Shapiro, A McGarry Houghton, Jay K Kolls, Mingquan Zheng
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20333 (2011)
Chronic Obstructive Pulmonary Disease (COPD) is characterized by airspace enlargement and peribronchial lymphoid follicles; however, the immunological mechanisms leading to these pathologic changes remain undefined. Here we show that cigarette smoke
Externí odkaz:
https://doaj.org/article/50301d1cf40c4f6384de173cb992c82e
Autor:
Derek A. Pociask, Shulin Qin, Mingquan Zheng, Sun Mi Choi, Mark H. Kaplan, Todd A. Reinhart, Jay K. Kolls, Jeremy P. McAleer
Publikováno v:
The Journal of Experimental Medicine
STAT3-mediated induction of Reg3γ enhances bacteriostatic and bactericidal activity to pulmonary Staphylococcus aureus.
Pulmonary Staphylococcus aureus (SA) infections are a public health concern and a major complication of hyper-IgE syndrome,
Pulmonary Staphylococcus aureus (SA) infections are a public health concern and a major complication of hyper-IgE syndrome,
Autor:
Jeremy P. McAleer, Derek A. Pociask, Jay K. Kolls, Sun-Mi Choi, Kong Chen, Rachel A. Armentrout, Giraldina Trevejo-Nunez
The incidence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) pneumonia in previously healthy individuals has increased in the past 5 years. Such infections are associated with bronchiectasis and high mortality rates, makin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0feaae1fd7dc1b71ae46f4bdaa1126cf
https://europepmc.org/articles/PMC3993390/
https://europepmc.org/articles/PMC3993390/
Autor:
Derek A. Pociask, Charles W. Andrews, Amy M. Scurlock, Toni Darville, Melissa M. Riley, Jeanne E. Sullivan, Matthew A. Zurenski, Lauren C. Frazer, Margaret Mintus
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 70(6)
Objective Chlamydia trachomatis infections are a significant cause of reproductive tract pathology. Protective and pathological immune mediators must be differentiated to design a safe and effective vaccine. Methods Wild-type mice and mice deficient
Autor:
Joseph D. Latoche, Derek A. Pociask, Yvonne R. Chan, Jay K. Kolls, Alison J. Logar, Kong Chen, Steven R. Duncan, Kira L. Lathrop, Anuradha Ray, Joseph M. Pilewski, Brendon Wahlberg, Prabir Ray
Publikováno v:
The Journal of allergy and clinical immunology. 131(4)
Background IL-17 is an important cytokine signature of the T H differentiation pathway T H 17. This T-cell subset is crucial in mediating autoimmune disease or antimicrobial immunity in animal models, but its presence and role in human disease remain
γδ T cells are a subset of T cells associated with epithelial mucosal tissues and play a prominent role in both promoting and dampening inflammatory responses to pathogens; in addition, they strongly mediate epithelial repair. By using a bleomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdc3be92857932375db98e75d934bb5
https://europepmc.org/articles/PMC3070585/
https://europepmc.org/articles/PMC3070585/